GSTA1_HUMAN_1_222

Glutathione S-transferase A1 [GST superfamily. Alpha family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains homodimer[show domain annotation]
 • A1 (GSTA1_HUMAN):D: GST N-terminal (9,10,13:15,45,54:56,67,68)
R: Glutathione binding (54,55)
R: Glutathione binding (67,68)
D: GST C-terminal (106:108,110,111)
208,212,213,216,220,222
9,10,13:15,45,54:56,67,68,106:108,110,111,208,212,213,216,220,222
 • A2 (GSTA1_HUMAN):D: GST C-terminal (101,131)101,131

Full PDB list

1gsd,1gse,1gsf,1guh,1k3l,1k3o,1k3y,1pkw,1pkz,1pl1,1pl2,1usb,1xwg,1ydk,2r3x,2r6k,3i69,3i6a,3ik9,3ktl,3l0h,3q74,3u6v,3zfb,3zfl,4hj2,5jcu (redundant pocketome entry); 1ags (unprocessed)

Contact map

[download in TSV format]
   
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ligand
A1 A2
Y
9
F
1
0
R
1
3
G
1
4
R
1
5
R
4
5
Q
5
4
V
5
5
P
5
6
Q
6
7
T
6
8
I
1
0
6
L
1
0
7
L
1
0
8
P
1
1
0
V
1
1
1
M
2
0
8
S
2
1
2
L
2
1
3
A
2
1
6
F
2
2
0
F
2
2
2
D
1
0
1
R
1
3
1
[1]1pl1.a aby 26 . . . . . . . . . . . . . . . . . . . . . . . .
[1]1guh.a gsb 27 . . . . . . . . . . . . . . . . . . . . . . . .
[1]1gse.a gsh.eaa 39 . . . . K . . . . . . . . . . . . . . . . . . .
[2]3ik9.a bob 31 . . . . . . . . . . . . I M . F P Y V V . - . .
[2]3ik9.b bob 31 . . . . . . . . . . . . I M . F P Y V V . P . .
[1]4hj2.a lz6 38 . . . . . . . . . . . . . . . . . . . . . - . .
[1]1pl2.a aby 26 . . . . . . . . . . E . . . . . . . . . . . . .
[1]1gsf.a eaa 19 . . . . . . . . . . . . . . . . . . . . . . . .
[1]1k3y.a gtx 26 . . . . . . . . . . . . . . . . . . . . . . . .
[1]1pkw.a gsh 20 . . . . . . . . . . . . . . . . . . . . . . . .
[1]1pkz.b none . . . . . . . . . . . . . . . . . . . . - - . .
[1]2r3x.a gtx 26 . . . . L . . . . . . . . . . . . . . . . . . .
[1]1usb.a gsh 20 . . . . . . . . . . . . . . . . . . . H . - . .
[1]1xwg.b none . . . . . . . . . . E . . . . . . . . . . . . .
[2]3i69.a none . . . . . . . . . . . . I M . F P Y V V . - . .
[2]3i6a.b gsh 20 . . . . . . . . . . . . I M . F P Y V V . P . .
[2]3i6a.d gsh 20 . . . . . . . . . . . . I M . F P Y V V . - . .
[1]5jcu.a gvx 31 . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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