GCN2_YEAST_593_997_ATPsite

eIF-2-alpha kinase GCN2 [Protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (GCN2_YEAST):D: Protein kinase 2 (605:607,613,626,628,656,789:791,835,837,840,842,853)605:607,613,626,628,656,789:791,835,837,840,842,853

Full PDB list

1zxe,1zy4,1zy5,1zyc,1zyd (redundant pocketome entry)

Contact map

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ligand
A1
L
6
0
5
G
6
0
6
Q
6
0
7
V
6
1
3
A
6
2
6
K
6
2
8
V
6
5
6
E
7
8
9
Y
7
9
0
C
7
9
1
D
8
3
5
K
8
3
7
N
8
4
0
F
8
4
2
D
8
5
3
[1]1zy5.a anp,mg 32 . . . . . . . . . . . . . . .
[1]1zxe.a none . . . . . . . . . . N . . . .
[1]1zy4.b none . . . . . . . . . . . . . . .
[1]1zyd.a atp,mg,mg 33 . . . . . . . . . . . . . . .
[1]1zyd.b atp,mg 32 . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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