GAK_HUMAN_12_350

Cyclin-G-associated kinase [Protein kinase superfamily. Ser/Thr protein kinase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (GAK_HUMAN):D: Protein kinase (44,46,47,54,67,69,85,89,99,121,123:129,177,178,180,190,191)44,46,47,54,67,69,85,89,99,121,123:129,177,178,180,190,191

Full PDB list

4c57,4c58,4c59,4o38,4y8d (redundant pocketome entry)

Contact map

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ligand
A1
R
4
4
L
4
6
A
4
7
V
5
4
A
6
7
K
6
9
E
8
5
M
8
9
V
9
9
L
1
2
1
T
1
2
3
E
1
2
4
L
1
2
5
C
1
2
6
K
1
2
7
G
1
2
8
Q
1
2
9
E
1
7
7
N
1
7
8
L
1
8
0
C
1
9
0
D
1
9
1
[1]4y8d.b 49j 24 . . . . . . . . . . . . . . . . . . . . . .
[1]4c58.a 824 25 . . . . . . . . . . . . . . . . . . . . . .
[1]4c57.a fef 27 . . . . . . . . . . . . . . . . . . . . . .
[1]4o38.b none . . . . . . . * . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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