FLT3_HUMAN_600_952

Receptor-type tyrosine-protein kinase FLT3 [Protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (FLT3_HUMAN):D: Protein kinase (616,624,642,644,661,665,668,675,691,693:695,697,809,818,828:830)616,624,642,644,661,665,668,675,691,693:695,697,809,818,828:830

Full PDB list

1rjb,4rt7,4xuf (redundant pocketome entry)

Contact map

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ligand
A1
L
6
1
6
V
6
2
4
A
6
4
2
K
6
4
4
E
6
6
1
M
6
6
5
L
6
6
8
V
6
7
5
F
6
9
1
Y
6
9
3
C
6
9
4
C
6
9
5
G
6
9
7
H
8
0
9
L
8
1
8
C
8
2
8
D
8
2
9
F
8
3
0
[1]4rt7.a p30 40 . . . . . . . . . . . . . . . . . .
[1]1rjb.a none . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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