FGFR4_HUMAN_444_753

Fibroblast growth factor receptor 4 [Protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (FGFR4_HUMAN):D: Protein kinase (473:478,481,501:503,520,523,524,527,533,534,548,550:554,556,557,560,608:611,616,619,628:631,633)473:478,481,501:503,520,523,524,527,533,534,548,550:554,556,557,560,608:611,616,619,628:631,633

Full PDB list

4qq5,4qqc,4qqj,4qqt,4qrc,4r6v,4tye,4tyg,4tyi,4tyj,4uxq,4xcu,5jkg (redundant pocketome entry)

Contact map

[download in TSV format]
   
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ligand
A1
L
4
7
3
G
4
7
4
E
4
7
5
G
4
7
6
C
4
7
7
F
4
7
8
V
4
8
1
A
5
0
1
V
5
0
2
K
5
0
3
E
5
2
0
V
5
2
3
M
5
2
4
I
5
2
7
I
5
3
3
I
5
3
4
V
5
4
8
V
5
5
0
E
5
5
1
C
5
5
2
A
5
5
3
A
5
5
4
G
5
5
6
N
5
5
7
E
5
6
0
C
6
0
8
I
6
0
9
H
6
1
0
R
6
1
1
R
6
1
6
L
6
1
9
I
6
2
8
A
6
2
9
D
6
3
0
F
6
3
1
L
6
3
3
[1]5jkg.a 6lf 30 . . . . A . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4xcu.a 40m 35 . . . - - - . . . . . . . . . . . . . * . . . . . . . . . . . . . . . .
[1]4tyi.a 38o 29 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4qq5.a 37o 47 . . . . * . . . . . . . . . . . . L . . . . . . . . . . . . . . . . . .
[1]4r6v.a fi3 48 . . . . * . . . . . . . . . . . . L . . . . . . . . . . . . . . . . . .
[1]4qqj.a none . . . - - - . . . . . . . . . . . L . . . . . . . . . . . . . . . . . .
[1]4tyj.a 0li 39 . . . . - - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4qqc.a 37o 47 . . . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4uxq.a 0li 39 . . . . A . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[2]4tyg.a none . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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