FES_HUMAN_552_822

Tyrosine-protein kinase Fes/Fps [Protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (FES_HUMAN):D: Protein kinase (567:570,575,588,590,607,636:640,642,643,646,687,688,690,700,701)567:570,575,588,590,607,636:640,642,643,646,687,688,690,700,701
Cofactors (cF):aceIYESL

Full PDB list

3bkb,3cbl,3cd3,4e93 (redundant pocketome entry)

Contact map

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ligand
A1 cF
I
5
6
7
G
5
6
8
R
5
6
9
G
5
7
0
V
5
7
5
A
5
8
8
K
5
9
0
E
6
0
7
M
6
3
6
E
6
3
7
L
6
3
8
V
6
3
9
Q
6
4
0
G
6
4
2
D
6
4
3
T
6
4
6
R
6
8
7
N
6
8
8
L
6
9
0
S
7
0
0
D
7
0
1
[1]4e93.a gui 42 . . . . . . . . . . . . . . . . . . . . .
[1]3cbl.a stu 35 . . . . . . . . . . . . . . . . . . . . . aceIYESL

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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