F16P1_PIG_2_337_catalytic

Fructose-1,6-bisphosphatase 1 [FBPase class 1 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains homodimer[show domain annotation]
 • A1 (F16P1_PIG):R: Substrate binding (122:125)
R: Substrate binding (213,216)
R: Substrate binding (245,247:249)
R: Substrate binding (275:277)
69,98,265,281
69,98,122:125,213,216,245,247:249,265,275:277,281
 • A2 (F16P1_PIG):R: Substrate binding (244)244
Metals (Me):Mg/Mn/Tl/Zn/K

Full PDB list

1cnq,1eyi,1eyj,1eyk,1fbc,1fbd,1fbe,1fbf,1fbg,1fbh,1fbp,1fj6,1fj9,1fpb,1fpd,1fpe,1fpf,1fpg,1fpi,1fpj,1fpk,1fpl,1frp,1fsa,1kz8,1lev,1nuw,1nux,1nuy,1nuz,1nv0,1nv1,1nv2,1nv3,1nv4,1nv5,1nv6,1nv7,1q9d,1rdx,1rdy,1rdz,1yxi,1yyz,1yz0,2f3b,2f3d,2fbp,2qvu,2qvv,3fbp,4fbp,4gbv,4gbw,4gws,4gwu,4gww,4gwx,4gwy,4gwz,4gx3,4gx4,4gx6,4h45,4h46,4kxp,5fbp (redundant pocketome entry)

Contact map

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ligand
A1 A2 Me
D
6
9
E
9
8
D
1
2
2
G
1
2
3
S
1
2
4
S
1
2
5
N
2
1
3
Y
2
1
6
Y
2
4
5
G
2
4
7
S
2
4
8
M
2
4
9
Y
2
6
5
K
2
7
5
L
2
7
6
R
2
7
7
E
2
8
1
R
2
4
4
[1]1fbh.a afp,fbp 40 . . . . . . . . . . . . . . . . . .
[1]4fbp.a none - . . . . . . . . . . . . . . . . .
[1]1fpk.a tl 1 - . . . . . . . . . . . . . . . . . Tl
[1]2qvu.a fdp,mg 21 . . . . . . . . . . . . . . . . . . Mg
[1]1fj6.a f6p,zn 17 . . . . . . . . . . . . . . . . . . Zn
[1]2qvv.a fdp 20 . . . . . . . . . . . . . . . . . . Zn
[1]1nuw.a f6p,mg 17 . . . . . . . . . . . . . . . . . . Mg
[1]1fbg.a ahm 19 - . . . . . . . . . . . . . . . . . Mn
[1]1fpd.a ahg 19 - . . . . . . . . . . . . . . . . . Mn
[1]1rdz.a f6p 16 . . . . . . . . . . . . . . . . . A
[1]1fpi.a ahg,k 20 - . . . . . . . . . . . . . . . . . K
[1]1nv2.a f6p,tl 17 . . . . . . . . . . . . . . . . . . Mg
[1]1fpj.a ahg,tl 20 - . . . . . . . . . . . . . . . . . Tl
[1]4gbw.a f6p,mn 17 . . . . . . . . . . . . . . . . . . Mn
[1]4gww.a f6p 16 - . . . . . . . . . . . . . . . . . Mg

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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