EST1_HUMAN_20_559

Liver carboxylesterase 1 [Type-B carboxylesterase/lipase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (EST1_HUMAN):90,92,93,96,97,101,141:143,146,221,222,252,254,255,299,302:305,317,318,358,359,362:364,388,425,426,46890,92,93,96,97,101,141:143,146,221,222,252,254,255,299,302:305,317,318,358,359,362:364,388,425,426,468

Full PDB list

1mx1,1mx5,1ya4,1ya8,1yah,2dqy,2dqz,2dr0,2h7c,2hrq,2hrr,3k9b,4ab1,5a7f,5a7g,5a7h (redundant pocketome entry)

Contact map

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ligand
A1
D
9
0
K
9
2
A
9
3
L
9
6
L
9
7
F
1
0
1
G
1
4
1
G
1
4
2
G
1
4
3
V
1
4
6
S
2
2
1
A
2
2
2
T
2
5
2
V
2
5
4
L
2
5
5
L
2
9
9
K
3
0
2
F
3
0
3
L
3
0
4
S
3
0
5
P
3
1
7
L
3
1
8
L
3
5
8
I
3
5
9
Q
3
6
2
L
3
6
3
M
3
6
4
L
3
8
8
M
4
2
5
F
4
2
6
H
4
6
8
[1]1ya4.c ctx 28 . . . . . . . . . . . . . . . . . . . . . . . . - . . . . . .
[1]1ya8.b smb 7 . . . . . . . . . . . . . . . . . . . . . . . . - . . . . . .
[1]2dr0.a tch 35 . . . . . . . . . . . . . . . . . . . . . . . . - . . . . . .
[1]1mx5.b htq 20 . . . . . . . . . . . . . . . . . . . . . . . . - . . . . . .
[1]3k9b.a ww2 10 . . . . . . . . . . * . . . . . . . - - - - . . - . . . . . .
[1]3k9b.b ww2 10 . . . . . . . . . . * . . . . . . - - - S . . . - . . . . . .
[1]3k9b.c ww2 10 . . . . . . . . . . * . - . . . . - - - - . . . L - - - . . .
[1]1mx1.c tha 15 . . . . . . . . . . . . . . . . . . . . . . . . - . . . . . .
[1]2hrq.b gd7 10 . . . . . . . . . . * . . . . . . . . . . . . . - . . . . . .
[1]2hrr.b ntj 8 . . . . . . . . . . * . . . . . . . . . . . . . - . . . . . .
[1]1yah.b eee 6 . . . . . . . . . . . . . . . . . . . . . . . . - . . . . . .
[1]2dqz.b plm 11 . . . . . . . . . . . . . . . . . . . . . . . . - . . . . . .
[1]2h7c.b coa 48 . . . . . . . . . . . . . . . . . . . . . . . . - . . . . . .
[1]5a7f.a none . . . . . . . . . . . . . . . . . . . . . . . . - . . . . . .
[1]5a7g.a none . . . . . . . . . . A . . . . . . . . . - . . . - . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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