ERYK_SACEN_1_397

Erythromycin C-12 hydroxylase [Cytochrome P450 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (ERYK_SACEN):R: Substrate binding (74,75)
72,73,155,158:160,163,172,176,223,226,227,230,231,274,276,278,378,379
72:75,155,158:160,163,172,176,223,226,227,230,231,274,276,278,378,379
Cofactors (cF):hem
Metals (Me):Fe

Full PDB list

2jjn,2jjo,2jjp,2wio,2xfh,3zkp (redundant pocketome entry)

Contact map

[download in TSV format]
   
PDB.ch
   
ligand
A1 cF Me
M
7
2
I
7
3
H
7
4
E
7
5
L
1
5
5
I
1
5
8
Q
1
5
9
M
1
6
0
P
1
6
3
I
1
7
2
L
1
7
6
A
2
2
3
L
2
2
6
A
2
2
7
I
2
3
0
T
2
3
1
F
2
7
4
Q
2
7
6
Q
2
7
8
I
3
7
8
V
3
7
9
[1]2xfh.a cl6 25 . . . . . . . . . . . . . . . . . . . . . hem Fe
[1]2jjp.a kln 36 . . . . . . . . . . . . . . . . . . . . . hem Fe
[1]2jjo.a ey5 49 . . . . . . . . . . . . . . . . . . . . . hem Fe
[1]3zkp.a erb 50 A . . . . . . . . . . . . . . . . . . . . hem Fe
[1]2jjn.a none . . . . . . . . . . . . . . . . . . . . . hem Fe

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
Similar entries
Feedback