ERAP1_HUMAN_39_529

Endoplasmic reticulum aminopeptidase 1 [Peptidase M1 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (ERAP1_HUMAN):R: Substrate binding (317:320)
181,183,316,353,354,357,376,380,383,433,438
181,183,316:320,353,354,357,376,380,383,433,438
Metals (Me):Zn

Full PDB list

2yd0,3mdj,3qnf (redundant pocketome entry)

Contact map

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ligand
A1 Me
Q
1
8
1
E
1
8
3
S
3
1
6
G
3
1
7
A
3
1
8
M
3
1
9
E
3
2
0
H
3
5
3
E
3
5
4
H
3
5
7
E
3
7
6
K
3
8
0
E
3
8
3
F
4
3
3
Y
4
3
8
[1]2yd0.a bes 22 . . . . . . . . . . . . . . . Zn
[1]3qnf.b none . . . . . . . . . . . . . . . Zn

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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