EP300_HUMAN_1043_1161

Histone acetyltransferase p300

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (EP300_HUMAN):D: Bromo (1070,1073:1075,1077,1079,1084,1086,1089,1128,1131,1132,1137,1138)
1141
1070,1073:1075,1077,1079,1084,1086,1089,1128,1131,1132,1137,1138,1141

Full PDB list

3i3j,4bhw,5bt3,5lkt,5lku,5lkx,5lkz (redundant pocketome entry)

Contact map

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ligand
A1
P
1
0
7
0
L
1
0
7
3
P
1
0
7
4
F
1
0
7
5
Q
1
0
7
7
V
1
0
7
9
L
1
0
8
4
I
1
0
8
6
Y
1
0
8
9
A
1
1
2
8
Y
1
1
3
1
N
1
1
3
2
R
1
1
3
7
V
1
1
3
8
Y
1
1
4
1
[1]5bt3.a 2lo 36 . . . . . . . . . . . . . . .
[1]5lku.a none . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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