If you see this message after the page is completely loaded, then JavaScript is not supported or disabled in your browser. Please consider enabling JavaScript for this site.

EFTU1_THET8_2_406

Elongation factor Tu-A [TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily]

Composition of the binding site

Protein chains monomer
A1 (EFTU1_THET8):230, 232, 235, 238, 240, 270:272, 275, 288:290230, 232, 235, 238, 240, 270:272, 275, 288:290

Full PDB list

1aip, 1b23, 1ob5, 1ttt, 1tui, 2c78, 4h9g, 4lbv, 4lbw, 4lby, 4lbz, 4lc0 (redundant Pocketome entry)

Pocket contact map

[download in TSV format]
   
PDB.ch
   
ligand
A1
F
2
3
0
I
2
3
2
R
2
3
5
V
2
3
8
G
2
7
0
V
2
7
1
E
2
7
2
R
2
7
5
G
2
8
8
V
2
8
9
L
2
9
0
[1]1b23.p A,mg23 . . . . . . . . . L .
[1]1ttt.a A22 . . . . . . . . . L .
[1]1tui.a none . . . . . . . . . L .
[1]4h9g.a 14j9 . . . . . . . . . . .
[1]4lbw.a none . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)

Site contact map

[download in TSV format]
   
PDB.ch
A1
F
2
3
0
I
2
3
2
R
2
3
5
V
2
3
8
T
2
4
0
G
2
7
0
V
2
7
1
E
2
7
2
R
2
7
5
G
2
8
8
V
2
8
9
L
2
9
0
[1]1b23.p . . . . . . . . . . L .
[1]1ttt.a . . . . . . . . . . L .
[1]1tui.a . . * . . . . . . . L .
[1]4h9g.a . . * . . . . . . . . .
[1]4lbw.a . . * . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)

Pocket-ligand steric compatibility

Ligands (x) vs pockets (y) colored by number of steric clashes

zoom: [−] [+]; [view as image]; [download as text]

pocketligand
≥10
9
8
7
6
5
4
3
2
1
0
1b23.p:A,mg
1ttt.a:A
1tui.a is apo
4h9g.a:14j
4lbw.a is apo
[1] 1b23.p
0.1
0.2 - 0.5 -
[1] 1ttt.a 0.3
0
- 0 -
[1] 1tui.a 1.7 1.4
-
0.8 -
[1] 4h9g.a 1.7 1.6 -
0.1
-
[1] 4lbw.a 1.3 1.1 - 0.4
-
[Pocket-ligand steric clashes matrix]

Pocket clash dissimilarity (1 cluster)

Pockets (x) vs pockets (y) colored by ligand clash profile difference

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥1.
.9
.8
.7
.6
.5
.4
.3
.2
.1
.0
1b23.p
1ttt.a
1tui.a
4h9g.a
4lbw.a
[1] 1b23.p
0
.06 .15 .16 .14
[1] 1ttt.a .06
0
.14 .15 .12
[1] 1tui.a .15 .14
0
.17 .10
[1] 4h9g.a .16 .15 .17
0
.07
[1] 4lbw.a .14 .12 .10 .07
0
[Pocket clash dissimilarity matrix]

Site backbone RMSD (median 1.3 Å)

Pockets (x) vs pockets (y) colored by RMSD of site residue backbone atoms

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥10 Å
9 Å
8 Å
7 Å
6 Å
5 Å
4 Å
3 Å
2 Å
1 Å
0 Å
1b23.p
1ttt.a
1tui.a
4h9g.a
4lbw.a
[1] 1b23.p
0
0.4 0.8 0.4 0.4
[1] 1ttt.a 0.4
0
0.8 0.4 0.3
[1] 1tui.a 0.8 0.8
0
0.7 0.8
[1] 4h9g.a 0.4 0.4 0.7
0
0.1
[1] 4lbw.a 0.4 0.3 0.8 0.1
0
[Binding site backbone RMSD matrix]

Site full-atom RMSD (median 0.4 Å)

Pockets (x) vs pockets (y) colored by RMSD of all site residue atoms

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥10 Å
9 Å
8 Å
7 Å
6 Å
5 Å
4 Å
3 Å
2 Å
1 Å
0 Å
1b23.p
1ttt.a
1tui.a
4h9g.a
4lbw.a
[1] 1b23.p
0
1.3 1.9 1.7 1.0
[1] 1ttt.a 1.3
0
1.8 1.4 1.0
[1] 1tui.a 1.9 1.8
0
1.8 1.6
[1] 4h9g.a 1.7 1.4 1.8
0
0.5
[1] 4lbw.a 1.0 1.0 1.6 0.5
0
[Binding site full-atom RMSD matrix]







[show 3D visualization]

[ENTRY 2D visualization]

L C X E | Background Color: | Anaglyph Stereo:

loading...