E2AK3_HUMAN_581_1092

Eukaryotic translation initiation factor 2-alpha kinase 3 [Protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (E2AK3_HUMAN):D: Protein kinase (599,607,620:622,624,639,642,643,646,651,652,886,888:893,928,933,935,944,954:956,958)599,607,620:622,624,639,642,643,646,651,652,886,888:893,928,933,935,944,954:956,958

Full PDB list

4x7h,4x7j,4x7k,4x7l,4x7n4g31,4g34,4m7i,4x7o (unprocessed)

Contact map

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ligand
A1
L
5
9
9
V
6
0
7
A
6
2
0
I
6
2
1
K
6
2
2
I
6
2
4
E
6
3
9
A
6
4
2
L
6
4
3
L
6
4
6
I
6
5
1
V
6
5
2
I
8
8
6
M
8
8
8
Q
8
8
9
L
8
9
0
C
8
9
1
R
8
9
2
K
8
9
3
L
9
2
8
L
9
3
3
H
9
3
5
F
9
4
4
G
9
5
4
D
9
5
5
F
9
5
6
L
9
5
8
[1]4x7j.a 3z1 35 . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4x7l.a 3z4 40 . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4x7n.a 3z5 40 . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4x7k.a 3z3 42 . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4x7h.a 3z2 43 . . . . . . . . . . . . . . . . . . . . . . . . . . -

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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