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DYR_HUMAN_2_187

Dihydrofolate reductase [Dihydrofolate reductase family]

Composition of the binding site

Protein chains monomer [domain annotation]
A1 (DYR_HUMAN):D: DHFR (8:10, 17, 18, 20:23, 25, 27, 29:36, 53:57, 60:62, 64, 65, 68, 69, 71, 76:79, 91:93, 116:122, 124, 137, 147)
R: Substrate binding (31:36)
8:10, 17, 18, 20:23, 25, 27, 29:36, 53:57, 60:62, 64, 65, 68, 69, 71, 76:79, 91:93, 116:122, 124, 137, 147
Cofactors (cF):nap/ndp

Full PDB list

1boz, 1dhf, 1dlr, 1dls, 1drf, 1hfp, 1hfq, 1hfr, 1kms, 1kmv, 1mvs, 1mvt, 1ohj, 1ohk, 1pd8, 1pd9, 1pdb, 1s3u, 1s3v, 1s3w, 1u71, 1u72, 2c2s, 2c2t, 2dhf, 2w3a, 2w3b, 2w3m, 3eig, 3f8y, 3f8z, 3f91, 3fs6, 3ghc, 3ghv, 3ghw, 3gi2, 3gyf, 3l3r, 3n0h, 3ntz, 3nu0, 3nxo, 3nxr, 3nxt, 3nxv, 3nxx, 3nxy, 3nzd, 3oaf, 3s3v, 3s7a, 4ddr, 4g95, 4kak, 4kbn, 4kd7, 4keb, 4kfj, 4m6j, 4m6k, 4m6l, 4qhv, 4qjc, 5hpb, 5hqy, 5hqz, 5hsr, 5hsu, 5ht4, 5ht5, 5hui, 5hvb, 5hve (redundant Pocketome entry)

Pocket contact map

[download in TSV format]
   
PDB.ch
   
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[1]1boz.a prd25 . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]1dlr.a mxa24 . . . . . . . F . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]1dls.a mtx33 . . . . . . . Y . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]1drf.a fol32 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1hfp.a mot32 . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]1hfq.a mot32 . . . . . . . . . . S . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]1hfr.a mot32 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]1kms.a lih25 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]1kmv.a lii25 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]1mvt.a dtm27 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1ohk.a cop42 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]1pd9.a co428 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1pdb.a none . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1s3v.a tqd27 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1s3w.a tqt22 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . nap
[1]1u71.a mxa24 . . . . . . . R . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1u72.a mtx33 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]2c2s.b 34b22 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]2c2t.b 39b,39e42 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]2dhf.b dzf32 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2w3a.a top21 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]2w3b.a fol,vg959 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]3eig.a mtx33 . . . . . . . . . . R . . E . . . . . . . . . . . . . . . . . . . . .
[1]3f8y.a dh125 . . . . . . . . . . . . . K . . . . . . . . . . . . . . . . . . . . . ndp
[1]3f8z.a dh125 . . . . . . . . . . . . . S . . . . . . . . S . . . . . . . . . . . . ndp
[1]3f91.a dh125 . . . . . . . . . . . . . S . . . . . . . . F . . . . . . . . . . . . ndp
[1]3fs6.a dh125 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]3ghc.a ghc32 . . . . . . . . . . . . . S . . . . . . . . S . . . . . . . . . . . . ndp
[1]3ghv.a ghc32 . . . . . . . . . . . . . K . . . . . . . . F . . . . . . . . . . . . ndp
[1]3ghw.a ghw31 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]3gi2.a ghw31 . . . . . . . . . . . . . K . . . . . . . . . . . . . . . . . . . . . ndp
[1]3gyf.a 51p22 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]3l3r.a oag22 . . . . . . . . . . . . . K . . . . . . . . . . . . . . . . . . . . . ndp
[1]3n0h.a top,top42 . . . . . . . . . . . . . S . . . . . . . . F . . . . . . . . . . . .
[1]3ntz.a 3tz35 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]3nu0.a 3tu36 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]3nxo.a d2b24 . . . . . . . . . . . . . . . . . . . . . R . . . . . . . . . . . . . ndp
[1]3nxr.a d2d24 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]3nxt.a d2e24 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]3nxv.a d2f25 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]3nxx.a d2d,d2d50 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]3nxy.a d2h25 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]3nzd.a d2q.ndp80 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3oaf.a oag22 . . . . . . . . . . . . . S . . . . . . . . F . . . . . . . . . . . .
[1]3s3v.a top,top42 . . . . . . . . . . . . . K . . . . . . . . F . . . . . . . . . . . .
[1]3s7a.a 68435 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4ddr.a mmv26 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]4g95.a oag22 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4kak.b 06u28 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]4kbn.a 25u25 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]4kbn.b 25u,mg26 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]4kd7.a 9dr27 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]4keb.a 1qz32 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]4kfj.a 1r031 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]4kfj.b fol,mg33 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]4m6l.a 21v32 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . nap
[1]4qhv.a ixf23 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]4qjc.a ixe23 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]5hpb.a 63w23 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]5hqz.a 64j24 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]5hsr.a 63y,63y42 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]5hsu.a 63y21 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]5ht4.a 65j23 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]5ht5.a 65h22 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]5hui.a 65n25 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]5hvb.a 65o23 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]5hve.a 65q24 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)

Site contact map

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[1]1boz.a . . . . . . . . . . . . . . G . . . * . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]1dlr.a . . . . . . . . F . . * . . * * . . * . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]1dls.a . . . . . . . . Y . . . . . * . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]1drf.a . . . . . . . . . . . . . . * . . . . . . . . . . . . . * . . . . . . . . . . . . * . . . . . . .
[1]1hfp.a . . . . . . . . . . . . . . G . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]1hfq.a . . . . . . . . . . . . . . S . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]1hfr.a . . . . . . . . . . . . . . * . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]1kms.a . . . . . . . . . . . . . . * . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]1kmv.a . . . . . . . . . . . . . . * . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]1mvt.a . . . . . . . . . . . . . . * . . . * . . . * . . . . * * . . . . . . . . . . . . . . . . . . . .
[1]1ohk.a . . . . . . . . . . . . . . * . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]1pd9.a . . . . . . . . . . . . . . * . . . * . . . . . . . . . * . . . . . . . . . . . . . . . . . . . .
[1]1pdb.a . . . . . . . . . . . . . . * * . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1s3v.a . . . . . . . . . . . . . . * . . . * . . . * . . . . . * . . . . . . . . . . . . . . . . . . . .
[1]1s3w.a . . . . . . . . . . . . . . * . . . * . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . nap
[1]1u71.a . . . . . . . . R . . . . . * . . . * . . . . . . . . . * . . . . . . . . . . . . . . . . . . . .
[1]1u72.a . . . . . . . . . . . . . . * . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]2c2s.b . . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]2c2t.b . . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]2dhf.b . . . . . . . . . . . . . . * . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . .
[1]2w3a.a . . . . . . . . . . . . . . * . . . * . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]2w3b.a . . . . . . . . . . . . . . * . . . * . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]3eig.a . . . . . . * * . . . . . . R . . . E . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3f8y.a . . . . . . . . . . . . . . * . . . K . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]3f8z.a . . . . . . . . . . . . . . * . . . S . . . . . . . . . S . . . . . . . . . . . . . . . . . . . . ndp
[1]3f91.a . . . . . . . . . . . . . . * . . . S . . . . . . . . . F . . . . . . . . . . . . . . . . . . . . ndp
[1]3fs6.a . . . . . . . . . . . . . . * . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]3ghc.a . . . . . . . . . . . . . . * . . . S . . . . . . . . . S . . . . . . . . . . . . . . . . . . . . ndp
[1]3ghv.a . . . . . . . . . . . . . . * . . . K . . . . . . . . . F . . . . . . . . . . . . . . . . . . . . ndp
[1]3ghw.a . . . . . . . . . . . * . . * . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]3gi2.a . . . . . . . . . . . . . . * . . . K . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]3gyf.a . . . . . . . . . . . . . . * . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]3l3r.a . . . . . . . . . . . * . . * . . . K . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]3n0h.a . . . . . . . . . . . . . . * . . . S . . . . . . . . . F . . . . . . . . . . . . . . . . . . . .
[1]3ntz.a . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]3nu0.a . . . . . . . . . . . . . . * * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]3nxo.a . . . . . . . . . . . . . . * . . . * . . . . . . . . R * . . . . . . . . . . . . . . . . . . . . ndp
[1]3nxr.a . . . . . . . . * . . . . . * . . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]3nxt.a . . . . . . . . . . . . . . * . . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]3nxv.a . . . . . . . . . . . . . . * * . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]3nxx.a . . . . . . . . . . . . . . * . . . * . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]3nxy.a . . . . . . . . . . . . . . * * . . * . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]3nzd.a . . . . . . . . . . . * . . * . . . * . . . . . . . . . * . . . . . . . . . . . . . . . . . . . .
[1]3oaf.a . . . . . . . . . . . . . . * . . . S . . . . . . . . . F . . . . . . . . . . . . . . . . . . . .
[1]3s3v.a . . . . . . . . . . . . . . * . . . K . . . . . . . . . F . . . . . . . . . . . . . . . . . . . .
[1]3s7a.a . . . . . . . . . . . . . . . * . . . . . . . . . * . . * . . . . . . . . . . . . . . . . . . . .
[1]4ddr.a . . . . . . . . . . . * . . * . . . * . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]4g95.a . . . . . . . . . . . . . . * . . . * . . . . . . . . . * . . . . . . . . . . . . . . . . . . . .
[1]4kak.b . . . . . . . . . . . . . . * . . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]4kbn.a . . . . . . . . . . . * . . * . . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]4kbn.b . . . . . . . . . . . * . . * . . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]4kd7.a . . . . . . . . . . . * . . * . . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]4keb.a . . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]4kfj.a . . . . . . . . . . . . . . * . . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]4kfj.b . . . . . . . . . . . . . . * . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]4m6l.a . . . . . . . . . . . . . . * . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . nap
[1]4qhv.a . . . . . . . . . . . * . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]4qjc.a . . . . . . . . . . . . . . * * . . * . . . . . . . . * * . . . . . . . . . . . . . . . . . . . . ndp
[1]5hpb.a . . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]5hqz.a . . . . . . . . . . . . . . * . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]5hsr.a . . . . . . . . . . . . . . * . . . * . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]5hsu.a . . . . . . . . . . . . . . * . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]5ht4.a . . . . . . . . . . . . . . * . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]5ht5.a . . . . . . . . . . . . . . * . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]5hui.a . . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ndp
[1]5hvb.a . . . . . . . . . . . . . . * . . . . . . . . . . . . . * . . . . . . . . . . . . . . . . . . . . ndp
[1]5hve.a . . . . . . . . . . . . . . * . . . * . . . . . . . * . * . . . . . . . . . . . . . . . . . . . . ndp

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)

Pocket-ligand steric compatibility

Ligands (x) vs pockets (y) colored by number of steric clashes

zoom: [−] [+]; [view as image]; [download as text]

pocketligand
≥10
9
8
7
6
5
4
3
2
1
0
1boz.a:prd
1dlr.a:mxa
1dls.a:mtx
1drf.a:fol
1hfp.a:mot
1hfq.a:mot
1hfr.a:mot
1kms.a:lih
1kmv.a:lii
1mvt.a:dtm
1ohk.a:cop
1pd9.a:co4
1pdb.a is apo
1s3v.a:tqd
1s3w.a:tqt
1u71.a:mxa
1u72.a:mtx
2c2s.b:34b
2c2t.b:39b,39e
2dhf.b:dzf
2w3a.a:top
2w3b.a:fol,vg9
3eig.a:mtx
3f8y.a:dh1
3f8z.a:dh1
3f91.a:dh1
3fs6.a:dh1
3ghc.a:ghc
3ghv.a:ghc
3ghw.a:ghw
3gi2.a:ghw
3gyf.a:51p
3l3r.a:oag
3n0h.a:top
3ntz.a:3tz
3nu0.a:3tu
3nxo.a:d2b
3nxr.a:d2d
3nxt.a:d2e
3nxv.a:d2f
3nxx.a:d2d
3nxy.a:d2h
3nzd.a:d2q.ndp
3oaf.a:oag
3s3v.a:top
3s7a.a:684
4ddr.a:mmv
4g95.a:oag
4kak.b:06u
4kbn.a:25u
4kbn.b:25u,mg
4kd7.a:9dr
4keb.a:1qz
4kfj.a:1r0
4kfj.b:fol,mg
4m6l.a:21v
4qhv.a:ixf
4qjc.a:ixe
5hpb.a:63w
5hqz.a:64j
5hsr.a:63y
5hsu.a:63y
5ht4.a:65j
5ht5.a:65h
5hui.a:65n
5hvb.a:65o
5hve.a:65q
[1] 1boz.a
0
0 1.6 1.7 1.6 1.7 1.6 0.1 0.2 0 2.0 0 - 0.1 0 0.1 1.4 0.3 0.2 1.5 0.3 2.0 1.7 2.6 1.5 0.6 2.7 1.7 2.0 1.8 1.8 0 0.2 0.9 1.9 2.1 0.3 0.2 0.4 0.3 0.4 0.3 2.1 0.1 1.0 0.7 0.1 0 0.4 0.6 0.6 0.1 2.1 1.5 2.0 1.6 0.3 0.1 0.3 0.3 0.3 0 0 0.3 0.2 0 0.1
[1] 1dlr.a 0.9
0.1
4.5 4.6 4.7 4.4 4.4 1.0 1.3 1.4 7.7 1.5 - 1.3 0.6 0.6 5.0 0.8 0.8 4.4 1.0 5.4 4.7 5.1 5.2 3.4 5.5 4.8 5.2 4.4 4.8 0.5 1.0 2.9 6.0 6.0 0.7 1.0 0.6 1.4 1.5 1.4 1.3 0.7 2.9 3.4 0.7 0.8 1.2 1.2 1.1 1.0 2.8 2.3 4.0 5.4 2.6 0.9 1.5 2.5 0.8 0.2 1.0 1.6 1.8 0.2 0.5
[1] 1dls.a 0.5 0.1
0
0.2 0.3 0.3 0.2 0.1 0.3 0.5 0.7 0.4 - 0.4 0.3 0.4 0.2 0.2 0.3 0.2 2.1 0.8 0.5 0.9 0.9 0.8 0.9 0.4 0.5 0.4 0.4 0.2 0.5 2.1 1.5 0.9 0.5 2.1 0.4 2.6 2.3 2.0 1.3 0.6 1.9 1.2 2.2 0.6 1.1 0.8 1.4 0.6 1.9 1.5 0.2 0.9 0.4 0.4 0.1 0.2 0.7 0.3 0.8 0.1 1.0 0.3 0.7
[1] 1drf.a 0.2 0.6 0.2
0
0.3 0.3 0.2 0.1 0.3 0.2 0.1 0.5 - 0.1 0.3 0.6 0.3 0.3 0.3 0 1.9 0.8 0.6 0.7 0.6 0.2 0.7 0.3 0.6 0.3 0.3 0.2 0.1 1.4 2.1 1.0 0.4 2.4 0.7 2.1 2.2 2.0 3.1 0.6 1.8 1.1 2.3 1.0 1.4 0.6 0.7 0.3 1.8 1.0 0.2 0.7 0.3 0.2 0.4 0.1 0.6 0.4 1.0 0.3 0.4 0.5 0.5
[1] 1hfp.a 0.1 0.1 0.1 0.2
0.1
0 0 0.2 0 0.1 0.3 0.3 - 0 0.2 0.3 0.1 0.2 0.1 0.2 0.3 0.9 0.3 0.4 0.3 0.3 0.5 0.2 0.3 0.2 0.2 0 0.2 0.8 0.3 0.4 0.4 0.5 0.5 0.4 0.8 0.6 1.6 0.3 1.2 0.6 0.5 0.1 0.7 0.9 0.7 0.4 1.8 1.1 0.2 0.2 0.1 0.3 0 0 0.4 0.2 0 0 0.6 0.1 0.3
[1] 1hfq.a 0.1 0 0 0.2 0.4
0
0 0.2 0 0 1.6 0.1 - 0 0.1 0.1 0 0.1 0 0.3 0.4 0.4 0.3 0.3 0.3 0.2 0.4 0.2 0.2 0.2 0.2 0.1 0.1 1.0 0.3 0.4 0.3 0.4 0.5 0.3 0.5 0.3 1.2 0.1 1.0 0.5 0.5 0.1 0.6 0.8 0.5 0.4 1.7 0.8 0.2 0.3 0.1 0 0 0 0.1 0 0 0 0.6 0 0.2
[1] 1hfr.a 0 0.2 0.2 0.2 0.4 0.1
0.1
0 0.2 0.1 0.5 0.3 - 0 0.3 0.3 0.3 0.1 0.1 0.2 1.9 0.8 0.4 0.5 0.6 0.3 0.8 0.3 0.3 0.3 0.3 0 0 1.4 1.0 0.7 0.4 2.0 0.4 1.9 1.9 2.2 1.2 0.4 1.1 1.5 2.7 0.4 1.0 0.7 0.5 0.4 1.7 1.3 0.3 0.7 0.1 0.2 0.1 0 0.3 0.3 0.7 0.1 0.6 0.3 0.1
[1] 1kms.a 0.3 0.2 0.2 0.6 0.6 0.4 0.3
0
0.3 0.4 1.1 0.4 - 0.4 0.2 0.4 0.1 0.3 0.4 0.4 2.0 0.6 0.3 0.8 0.6 0.9 1.1 0.4 0.3 0.3 0.4 0.2 0.3 1.9 1.1 0.5 0.4 2.2 0.6 2.2 2.1 2.0 1.6 0.8 1.9 1.1 3.4 1.2 0.5 1.2 0.8 0.3 2.0 1.5 0.4 0.9 0.4 0.2 0 0.1 0.2 0.1 0.6 0.3 0.6 0.2 0.5
[1] 1kmv.a 0.3 0.3 0.1 0.4 0.4 0.2 0.2 0.2
0
0.1 0.8 0.1 - 0.3 0.3 0.4 0.4 0.3 0.3 0.3 1.6 0.6 0.4 0.4 0.5 0.4 0.7 0.2 0.2 0.2 0.2 0.2 0.4 1.3 0.7 0.4 0.4 1.9 0.6 2.2 2.1 1.5 1.4 0.2 1.3 0.6 2.4 0.3 1.6 1.4 1.2 0.9 2.5 2.0 0.3 0.6 0.5 0.2 0.3 0.1 0.4 0 0.6 0.3 1.0 0.1 0.5
[1] 1mvt.a 0.1 0.1 1.9 1.9 1.7 1.9 1.6 0.2 0.2
0
2.0 0 - 0.1 0.3 0.2 2.2 0.2 0.3 1.9 1.5 2.4 2.7 2.6 2.1 0.2 2.8 2.1 2.0 2.2 2.2 0.3 0 1.7 2.9 2.9 0.4 1.6 0.6 1.6 1.9 1.5 4.0 0.2 1.4 0.9 1.8 0.1 1.5 1.1 0.8 0.6 2.8 2.6 2.2 2.1 0.5 0.1 0.4 0.1 0.2 0.1 0.4 0.1 1.2 0.1 0.1
[1] 1ohk.a 0.3 0.4 0.2 0.3 0.2 0.1 0.1 0.1 0.3 0.3
0.5
0.3 - 0.2 0.3 0.3 0.1 0.3 0.3 0.2 1.8 0.4 0.3 0.6 0.6 0.6 0.7 0.1 0.4 0.1 0.1 0.3 0.2 1.5 1.0 0.5 0.4 1.8 0.4 2.3 2.1 1.8 2.1 0.5 1.3 1.0 2.0 0.5 0.5 0.6 0.6 0.4 1.2 1.0 0.1 1.0 0.2 0.2 0.1 0.1 0.3 0.3 0.8 0.2 0.4 0.4 0.3
[1] 1pd9.a 0 0.2 1.7 1.8 1.7 1.6 1.6 0.2 0.1 0 2.0
0
- 0 0 0 1.6 0.3 0.4 1.9 1.4 1.9 2.0 2.8 2.1 0.3 2.9 1.8 1.9 2.0 1.8 0.1 0.1 0.9 2.6 2.2 0.4 1.7 0.6 1.6 1.8 1.4 2.3 0.3 1.0 0.7 1.8 0.2 0.8 1.2 1.1 0.6 2.3 1.9 1.8 2.1 0.3 0.1 0.1 0 0.3 0.1 0.7 0.1 0.6 0 0.1
[1] 1pdb.a 0.3 0 1.8 1.7 1.5 1.9 1.5 0.2 0.2 0 3.8 0
-
0.1 0.1 0.1 1.7 0.3 0.3 1.8 1.1 2.2 2.1 2.0 2.0 0.3 2.1 2.0 2.2 2.1 2.1 0.2 0.3 0.7 2.3 2.4 0.5 1.3 0.6 1.5 1.8 1.2 0.9 0.1 0.8 0.4 2.0 0.1 0.7 1.2 0.9 0.6 2.0 1.4 2.2 1.6 0.2 0.1 0.1 0 0.3 0 0.4 0.1 0.3 0 0
[1] 1s3v.a 0 0.1 2.0 1.9 2.1 2.1 1.8 0 0.3 0 2.0 0.1 -
0
0 0.1 2.0 0.4 0.5 1.9 1.3 2.5 2.6 2.6 2.1 0.4 2.7 2.4 2.2 2.4 2.4 0.2 0.1 1.5 3.2 3.0 0.4 1.4 0.5 1.6 1.8 1.3 4.5 0.2 1.1 1.1 1.9 0.3 1.0 1.1 0.9 0.5 3.0 2.5 2.1 2.2 0.7 0 0.4 0.1 0.1 0 0.4 0 0.9 0 0.1
[1] 1s3w.a 0.5 0.1 3.2 3.7 3.6 3.1 3.5 0.3 0.5 0.8 4.2 0.7 - 0.7
0
0.1 3.3 0.2 0.1 4.3 0.5 4.9 3.6 5.9 5.2 3.2 6.3 4.1 4.1 3.9 3.7 0.2 0.7 3.0 5.3 5.0 0.5 0.2 0.6 0.3 0.4 0.3 0.9 0.1 3.1 2.2 0.3 0.1 0.8 0.9 0.8 0.7 2.9 2.6 3.8 5.0 1.6 0.1 1.2 1.9 0.5 0 0.8 0.9 1.3 0 0.3
[1] 1u71.a 0.4 0 3.6 3.9 4.0 3.4 3.4 0.2 0.3 0.6 4.3 0.6 - 0.7 0
0
4.0 0.2 0.2 4.1 0.4 4.6 4.1 4.5 4.7 2.9 5.1 3.9 3.8 3.6 3.9 0.1 0.4 2.6 5.1 4.8 0.4 0.4 0.4 0.8 0.8 0.7 2.3 0.2 2.8 2.8 1.0 0.2 1.1 0.9 0.9 0.8 2.7 2.5 4.1 4.8 1.4 0 1.2 2.2 0.3 0 0.8 0.9 1.3 0.1 0
[1] 1u72.a 0.2 0.3 0 0.1 0.2 0.2 0.2 0.2 0.3 0.2 0 0.2 - 0.1 0.2 0.2
0.1
0.1 0.1 0.1 2.0 0.6 0.4 0.6 0.5 0.4 0.8 0.2 0.4 0.2 0.2 0.2 0.4 1.7 1.4 0.7 0.4 2.3 0.4 2.0 2.2 1.9 1.4 0.4 1.6 1.4 2.2 0.5 1.1 0.7 0.5 0.5 1.8 1.2 0.1 0.7 0.1 0.2 0 0.1 0.4 0.3 0.7 0.1 0.7 0.4 0.3
[1] 2c2s.b 0.2 0 2.5 2.8 3.2 2.3 2.3 0 0.1 0.2 3.7 0.1 - 0.4 0 0.1 2.3
0
0 3.2 0.1 3.5 1.7 2.7 2.5 2.1 2.7 2.3 2.1 2.3 2.3 0 0.1 1.6 3.0 2.6 0 0 0 0.2 0.1 0.1 1.5 0 1.8 2.1 0.1 0 0 0.1 0.1 0.1 0.4 0.3 2.9 3.0 0.9 0 0.6 2.2 0.2 0 0.1 0.7 0.2 0 0.1
[1] 2c2t.b 0.2 0 2.5 3.0 3.4 2.3 2.5 0 0.1 0.3 3.9 0.1 - 0.4 0 0.1 2.4 0
0
3.3 0.1 3.4 1.7 2.7 2.5 2.1 2.7 2.2 2.1 2.3 2.2 0 0.2 1.6 3.0 2.6 0 0 0 0.2 0.1 0.1 1.3 0 1.8 2.3 0.1 0 0 0.1 0.1 0.1 0.5 0.3 2.9 3.1 0.9 0 0.6 2.2 0 0 0.1 1.0 0.2 0 0.3
[1] 2dhf.b 0.5 0.4 0.3 0.2 0.5 0.4 0.2 0.1 0.2 0.4 0.4 0.2 - 0.3 0.4 0.4 0.5 0.2 0.1
0.1
1.7 0.8 0.7 0.7 0.7 0.5 0.8 0.5 0.7 0.6 0.4 0.3 0.3 1.3 2.0 1.2 0.3 2.2 0.4 2.0 2.2 1.7 2.3 0.6 1.2 1.0 2.7 0.7 1.4 1.2 1.0 0.8 2.0 1.4 0.5 0.7 0.6 0.3 0.3 0.2 0.6 0.4 1.2 0.2 1.4 0.5 0.6
[1] 2w3a.a 0.2 0.1 4.1 4.4 4.6 3.9 4.0 0 0.2 0.3 4.4 0.2 - 0.4 0 0 3.7 0 0 4.6
0
4.9 3.8 4.9 4.4 2.4 4.7 3.8 3.8 3.7 3.7 0.1 0.2 2.1 5.2 5.0 0 0 0 0.1 0 0 1.4 0 2.1 2.1 0.1 0 0.1 0 0 0.2 1.8 1.7 4.4 5.0 1.3 0 0.8 2.2 0.1 0 0.3 0.7 0.5 0 0.1
[1] 2w3b.a 0.1 0 1.7 1.4 1.6 1.8 1.5 0.2 0.1 0 1.7 0 - 0 0 0.1 1.7 0.1 0 1.5 1.0
1.8
2.0 2.4 1.9 0.2 2.5 1.6 2.0 2.0 1.7 0 0.2 0.9 2.1 2.3 0.2 1.4 0.5 1.2 1.7 1.2 0.6 0.1 1.0 0.6 1.6 0 0.8 1.0 0.8 0.5 2.0 1.7 2.0 1.5 0.1 0 0.1 0 0.1 0 0.5 0.1 0.6 0 0.3
[1] 3eig.a 0.3 0.5 1.2 0.8 0.4 0.1 0.1 0.3 0.3 0.6 1.9 0.1 - 0.5 0.7 0.2 0.6 0.3 0.2 0.7 0.7 1.6
0
0.6 1.0 1.5 0.9 0.3 1.1 0.3 0.3 0.2 0.2 2.5 0.6 0.5 0.3 0.8 0.8 0.8 1.4 0.9 6.6 0.6 2.2 1.2 1.2 0.8 1.1 1.5 0.5 0.9 1.6 0.8 0.5 1.4 0.1 0.7 0 0.4 0.8 0.6 0.4 0.1 0.3 0.3 0.9
[1] 3f8y.a 0.1 0.1 0.2 0.1 0.1 0.2 0 0.2 0 0.2 0.3 0.1 - 0.1 0.1 0.2 0.3 0.1 0.1 0.1 1.2 0.2 0.3
0.1
0.1 0.1 0.2 0 0.1 0 0.1 0 0.2 0.8 0.9 0.3 0.1 1.5 0.5 1.6 1.9 1.3 1.5 0.2 0.9 0.2 2.2 0.2 1.2 1.2 0.9 0.7 2.8 1.9 0 0.3 0.3 0.1 0.5 0.1 0.4 0.2 0.9 0.2 1.0 0.2 0.5
[1] 3f8z.a 0 0 0.1 0 0.1 0 0 0.2 0.1 0.1 0.6 0 - 0 0 0.1 0.2 0.1 0.1 0 1.0 0.1 0.1 0.2
0.1
0 0.1 0 0 0 0.1 0 0 0.7 0.3 0.1 0.1 1.2 0.4 1.3 1.2 0.9 1.2 0.1 1.0 0.3 2.0 0.1 0.5 1.1 0.9 0.4 1.4 1.0 0 0 0.1 0 0.1 0.1 0.3 0 0.9 0.2 0.2 0 0.4
[1] 3f91.a 0 0 0.1 0 0.2 0 0 0.1 0 0.1 0.1 0.1 - 0 0 0.1 0.2 0.1 0.1 0 0.9 0.2 0.2 0.2 0
0
0.2 0.1 0 0.1 0.1 0 0.1 0.8 0.3 0.3 0.1 1.4 0.4 1.6 1.6 1.2 2.1 0.1 1.1 0.3 2.0 0 0.6 0.8 0.8 0.6 2.2 1.7 0 0.1 0.3 0 0.1 0 0.4 0 0.9 0.2 0.8 0 0.4
[1] 3fs6.a 0 0 0.1 0 0.1 0 0 0 0 0.1 0.3 0.1 - 0 0 0.2 0.3 0.1 0.1 0.1 1.0 0.2 0.1 0 0.1 0.1
0
0 0.1 0 0 0 0 0.8 0.4 0.2 0.1 1.4 0.4 1.4 1.5 1.1 1.4 0.2 0.8 0.3 2.0 0.1 1.0 1.3 0.8 0.7 2.0 1.4 0 0.2 0.3 0 0.1 0.1 0.4 0.2 0.9 0.3 0.8 0.1 0.5
[1] 3ghc.a 0.1 0.1 0 0 0.1 0 0 0.2 0 0.1 1.1 0.1 - 0.2 0.2 0.4 0 0.1 0.1 0 1.5 0.2 0.1 0.1 0.1 0 0.2
0
0 0 0 0 0.3 1.5 0.7 0 0.1 1.9 0.4 2.2 1.8 1.5 1.3 0.2 1.1 0.7 2.7 0.3 0.8 0.9 0.8 0.6 1.5 0.9 0 0.2 0.1 0.1 0.2 0.1 0.3 0.3 0.9 0.2 0.2 0.3 0.5
[1] 3ghv.a 0.1 0 0 0 0.2 0 0 0.2 0 0 0.3 0.2 - 0.3 0.2 0.3 0.1 0.1 0.1 0 1.4 0.5 0.2 0.3 0.1 0.1 0.3 0
0
0 0 0 0.3 1.3 0.8 0.3 0.1 1.8 0.4 1.9 1.8 1.6 2.4 0.3 1.5 0.7 2.8 0.3 1.0 0.9 0.8 0.7 2.3 1.7 0 0.2 0.3 0.1 0.1 0.1 0.4 0.3 0.9 0.2 0.9 0.3 0.6
[1] 3ghw.a 0.1 0 0.1 0.1 0.1 0 0 0.2 0 0 3.0 0.1 - 0.1 0.2 0.2 0.1 0.1 0.1 0 1.5 0.2 0.1 0.1 0 0.1 0.2 0 0
0
0 0 0.3 1.0 0.8 0.4 0.1 1.8 0.5 2.1 2.0 1.4 1.2 0.2 1.1 0.4 2.5 0.3 1.1 0.9 0.7 0.6 1.8 1.3 0 0.1 0.1 0 0.1 0.1 0.3 0.2 0.9 0.2 0.6 0.2 0.5
[1] 3gi2.a 0.1 0.1 0.1 0 0.2 0 0 0.2 0 0.1 1.1 0.1 - 0.3 0.2 0.3 0.1 0.1 0.1 0 1.5 0.2 0.2 0.1 0.1 0.1 0.3 0 0.1 0
0
0.1 0.3 1.2 0.8 0.5 0.1 1.9 0.5 2.6 2.0 1.4 1.3 0.2 1.3 0.5 2.8 0.3 1.2 1.1 0.7 0.8 2.1 1.7 0 0.2 0.1 0.1 0.3 0.2 0.3 0.2 0.9 0.2 0.6 0.3 0.5
[1] 3gyf.a 0.3 0.2 0.2 0.2 0.4 0.2 0.1 0.1 0.8 0.8 1.2 0.6 - 0.7 0.3 0.3 0.4 0.1 0.1 0.4 2.1 0.7 0.5 0.5 0.2 0.3 0.6 0.3 0.4 0.3 0.3
0
0.3 1.9 0.8 0.8 0.1 2.3 0.2 2.2 2.4 1.9 2.1 0.7 1.7 1.3 2.4 1.2 0.8 0.9 0.8 0.5 2.2 1.6 0.2 1.0 0.5 0.2 0.3 0.1 0.4 0.1 1.1 0.4 1.0 0.3 0.5
[1] 3l3r.a 0 0 0 0.3 0.2 0 0.1 0 0.3 0 1.4 0 - 0 0 0.1 0 0.3 0.2 0.2 1.2 0.2 0.1 0.4 0.4 0.2 0.4 0.3 0.4 0.3 0.3 0
0
1.1 0.8 0.3 0.1 1.7 0.2 1.4 1.4 1.4 1.6 0.1 0.8 0.6 1.8 0.5 0.4 0.8 0.5 0.2 1.8 0.9 0.2 0.6 0.3 0 0.1 0 0 0 0.5 0 0.5 0.1 0.3
[1] 3n0h.a 0 0 0.2 0.1 0.1 0.2 0 0 0 0.1 0.3 0.3 - 0.2 0.1 0.1 0.4 0.1 0.1 0.1 0.6 0.2 0.2 0.1 0 0.1 0.1 0 0.1 0 0.1 0 0.1
0
0.5 0.5 0.1 1.2 0.3 1.3 1.2 1.2 2.8 0.1 0.1 0.2 1.7 0.1 1.3 1.1 0.7 0.7 2.2 1.6 0.1 0 0.3 0 0.4 0.1 0.3 0.1 1.1 0.4 1.2 0.1 0.2
[1] 3ntz.a 0 0 0 0 0.2 0 0 0.2 0.2 0 1.0 0 - 0 0 0.1 0 0.1 0.1 0 0.3 0.1 0 0.1 0.2 0.1 0.1 0 0 0 0 0 0.2 0.8
0
0 0.1 0.4 0.3 0.8 0.5 0.4 1.0 0 0.9 0.1 1.0 0 0.5 1.0 0.5 0.3 1.9 0.9 0 0.1 0 0 0 0 0.1 0 0.2 0 0.4 0 0.3
[1] 3nu0.a 0.1 0 0.1 0 0.1 0 0 0 0.1 0 1.6 0 - 0 0.1 0.2 0 0.1 0.1 0 1.2 0.3 0 0.1 0.2 0.1 0.2 0 0 0 0 0 0.1 1.0 0.2
0
0.1 1.5 0.2 1.8 1.7 1.4 1.0 0.2 1.2 0.5 2.8 0.2 0.7 0.6 0.6 0.3 1.6 0.6 0 0.1 0 0 0 0 0.2 0.1 0.7 0.1 0.2 0.1 0.3
[1] 3nxo.a 0.5 0 3.4 3.4 3.9 3.6 3.6 0.1 0.2 0.6 4.3 0.4 - 0.6 0 0.1 3.8 0 0 3.8 0.2 4.6 3.7 4.9 4.7 2.7 5.4 3.7 3.5 3.7 3.7 0.1 0.2 2.4 5.2 5.1
0.1
0 0 0.2 0 0 1.5 0 2.7 2.1 0 0 0.7 0.5 0.3 0.7 2.4 1.8 3.9 4.5 1.3 0 1.1 2.3 0.3 0 0.7 1.1 0.7 0 0.3
[1] 3nxr.a 0.4 0 3.2 3.5 3.4 3.4 3.3 0.2 0.3 0.7 4.4 0.6 - 0.6 0 0.3 3.0 0 0.1 3.8 0.3 4.7 3.2 5.7 5.1 2.7 5.5 3.5 3.6 3.5 3.5 0.2 0.5 3.0 4.6 4.5 0.2
0
0 0.2 0 0 1.4 0 3.0 2.0 0.1 0 0.5 0.3 0.2 0.4 1.9 1.8 3.7 5.1 1.2 0 1.0 2.0 0.2 0 0.7 1.1 0.8 0 0.6
[1] 3nxt.a 0.4 0 3.2 3.2 3.4 3.0 3.0 0.2 0.5 0.5 3.9 0.7 - 0.6 0 0.1 2.9 0 0 3.1 0.5 4.3 3.0 5.3 4.7 2.7 5.3 3.4 3.6 3.6 3.4 0.2 0.4 2.7 4.7 4.0 0.2 0.1
0
0.3 0.1 0.1 1.5 0.1 2.7 2.0 0.2 0.1 0.2 0.1 0.2 0.3 1.2 1.2 3.5 4.6 1.1 0 0.7 1.9 0.4 0 0.9 1.1 0.6 0 0.1
[1] 3nxv.a 0.6 0.2 3.2 3.2 3.1 3.0 3.2 0.2 0.5 0.8 4.7 0.6 - 0.7 0 0.1 3.0 0 0.1 3.8 0.3 4.2 3.2 5.7 4.8 2.8 5.6 3.5 3.9 3.5 3.7 0.2 0.5 2.8 5.2 4.4 0.2 0 0
0
0 0 1.7 0 2.8 2.0 0.1 0 0.3 0.1 0.1 0.4 0.9 1.4 3.3 4.8 1.1 0 1.1 1.9 0.2 0.1 1.1 1.1 0.5 0 0.4
[1] 3nxx.a 0.4 0 3.5 3.4 3.7 3.5 3.6 0.2 0.3 0.5 4.3 0.6 - 0.6 0 0.1 3.9 0 0 3.8 0.4 4.3 3.2 5.3 4.7 2.6 5.5 3.5 3.6 3.5 3.5 0.2 0.5 2.8 5.1 4.3 0.2 0 0 0.1
0
0 1.8 0 3.0 1.9 0.1 0 0.9 0.6 0.5 0.5 2.8 2.1 3.8 4.6 1.2 0 1.2 2.0 0.2 0 0.7 0.9 1.3 0 0.3
[1] 3nxy.a 0.9 0.5 3.5 3.4 3.6 3.3 3.3 0.6 0.6 0.9 5.0 0.7 - 1.1 0 0.2 3.7 0.1 0.1 4.1 0.3 4.9 3.9 5.5 5.0 3.1 5.5 4.2 4.0 4.2 4.0 0.2 0.7 2.7 6.3 5.5 0.2 0 0.1 0 0
0
1.9 0 2.6 2.1 0.1 0 1.3 0.9 0.7 1.4 3.7 3.7 3.6 5.0 2.1 0 2.1 2.4 0.6 0 1.2 1.2 1.6 0.1 0.1
[1] 3nzd.a 0.4 0.2 3.6 3.9 3.7 3.4 3.5 0.3 0.1 0.8 5.9 0.6 - 0.7 0 0.2 3.5 0.2 0.4 4.3 0.7 5.0 3.5 5.4 5.5 3.2 5.6 3.6 4.2 3.8 3.6 0.4 0.6 3.4 5.5 5.2 0.6 0.3 0.8 0.4 0.6 0.3
0.8
0.2 3.2 2.4 0.2 0 1.3 1.5 0.9 0.8 3.4 2.9 4.6 5.1 1.6 0 1.5 2.0 0.4 0 0.8 1.3 1.5 0 0.1
[1] 3oaf.a 0.4 0.1 1.8 2.2 1.8 1.7 1.9 0.4 0.3 0.8 2.4 0.7 - 0.6 0 0 2.1 0.1 0.3 2.4 0.4 2.9 1.5 3.3 3.4 2.9 3.3 1.8 1.9 1.9 1.8 0.2 0.4 2.9 2.9 2.5 0.4 0.1 0.4 0.3 0.4 0.2 2.3
0
3.0 1.9 0 0 1.1 0.8 0.7 0.5 2.8 2.3 2.1 3.3 1.8 0 1.4 2.0 0.4 0 0.7 1.2 1.8 0 0.1
[1] 3s3v.a 0 0 1.9 1.3 1.9 1.8 1.7 0 0 0.1 1.7 0.4 - 0 0 0 2.1 0.1 0.1 1.3 0.5 1.8 1.9 2.0 1.5 0.1 2.0 1.6 1.6 1.6 1.6 0 0 0 2.4 2.3 0 1.1 0.2 1.3 1.3 1.2 3.3 0.1
0
0.3 2.0 0.2 1.1 0.9 0.7 0.5 2.9 2.3 1.5 1.3 0.3 0 0.2 0.2 0.3 0.1 0.9 0.2 1.3 0 0.2
[1] 3s7a.a 0.4 0.6 0.2 0.3 0.1 0.2 0 0.6 0.2 0.3 1.5 0.2 - 0.2 0.1 0.2 0.5 0.6 0.6 0.2 1.3 0.3 0.2 0.2 0.2 0.3 0.2 0.2 0.2 0 0.1 0.7 0.2 1.2 0.4 0.5 0.9 0.7 1.5 1.0 1.0 0.7 2.4 0.2 1.5
0
1.1 0 1.6 1.5 1.4 0.7 2.5 2.0 0.2 0.4 0.6 0.2 0.4 0 0.5 0 0.5 0.2 0.9 0.2 0.1
[1] 4ddr.a 0.8 0.2 4.6 4.8 4.3 4.3 4.1 0.3 0.3 0.7 5.6 0.8 - 0.7 0 0.2 4.4 0.2 0.2 4.6 0.5 5.8 4.7 5.4 4.9 3.4 5.4 4.3 4.5 4.5 4.3 0.3 0.8 2.8 6.2 5.5 0.5 0.1 0.5 0.3 0.5 0.3 1.1 0.1 2.6 2.7
0
0 1.9 1.2 0.8 1.0 3.9 3.3 4.5 5.7 2.4 0 1.9 2.1 0.5 0 0.9 1.7 1.8 0 0.1
[1] 4g95.a 0.5 0.3 3.6 3.4 3.6 3.0 3.2 0.4 0.3 0.9 4.4 0.6 - 1.1 0 0.2 3.6 0.2 0.4 3.5 0.5 4.2 3.7 5.3 4.9 3.0 5.7 3.5 3.6 3.4 3.2 0.4 0.6 3.2 5.1 5.3 0.3 0.1 0.5 0.3 0.5 0.2 1.7 0 3.2 2.1 0.1
0
2.1 1.3 0.9 1.3 3.6 3.1 3.3 4.9 1.8 0 1.7 2.2 0.6 0 1.0 1.1 2.0 0 0.1
[1] 4kak.b 0.1 0 4.2 4.3 5.0 4.4 4.3 0 0.1 0.2 5.3 0.1 - 0.1 0 0.1 3.9 0.1 0 4.6 0.2 5.5 3.4 4.5 4.2 2.1 4.8 4.0 4.0 4.3 4.3 0 0.1 1.7 4.7 4.5 0.1 0.2 0.2 0.2 0.3 0.3 1.0 0 1.7 2.2 0.1 0
0
0.2 0.1 0 0.7 0.8 5.3 4.1 0.9 0 0.6 2.2 0.1 0 0.1 0.9 0.2 0 0.3
[1] 4kbn.a 0.4 0.2 2.8 3.3 3.4 2.2 2.6 0.1 0.3 0.3 5.4 0.4 - 0.4 0.1 0.2 2.3 0.2 0.2 3.0 0.1 3.8 2.6 3.0 3.1 2.7 3.5 2.2 2.6 2.3 2.4 0.1 0.2 2.1 4.3 2.9 0.2 0 0.1 0.1 0 0.1 1.7 0 2.6 2.4 0.4 0 0.1
0
0 0.2 0.3 0.3 2.8 3.5 0.9 0.1 0.7 2.0 0.2 0.1 0.5 1.0 0.4 0.1 0.1
[1] 4kbn.b 0.6 0 3.9 3.6 4.3 3.8 4.0 0.1 0.4 0.6 6.7 0.4 - 0.6 0.1 0.2 3.8 0.2 0.2 3.8 0.3 5.3 3.5 5.0 4.7 2.7 5.2 3.9 4.1 3.4 3.9 0.1 0.2 2.4 5.0 4.6 0.2 0 0.1 0.2 0 0.1 0.9 0 2.5 2.5 0.4 0 0.2 0
0
0.2 1.0 0.8 4.0 4.6 1.2 0.1 0.9 2.0 0.3 0.1 0.5 1.0 0.4 0.1 0.1
[1] 4kd7.a 0.2 0 4.1 4.2 5.5 4.4 4.1 0 0.2 0.6 7.2 0.1 - 0.1 0.1 0.1 4.0 0.4 0.3 5.3 0.2 5.0 3.9 4.1 3.9 2.1 4.1 4.4 4.5 4.4 4.6 0.1 0.1 1.6 4.8 4.7 0.2 0.2 0.2 0.3 0.3 0.3 1.4 0.2 1.4 2.4 0.1 0 0.1 0.3 0.2
0
0.9 1.0 5.3 3.9 0.5 0.1 0.2 1.6 0.3 0 0.1 0.6 0.2 0 0.3
[1] 4keb.a 0.1 0 2.6 3.1 3.6 2.8 2.6 0 0.1 0.1 3.6 0.1 - 0.1 0.1 0.1 2.6 0 0 3.2 0.1 3.7 2.5 2.2 2.2 1.5 2.0 2.6 2.0 2.4 2.6 0 0.1 1.5 2.6 2.5 0 0 0 0.2 0 0.1 1.6 0 1.7 2.2 0.1 0 0 0.1 0.1 0
0.4
0.2 3.2 2.5 0.5 0 0.4 2.0 0 0 0.1 0.4 0.1 0 0.1
[1] 4kfj.a 0.1 0.2 3.2 3.3 3.8 3.3 3.3 0 0 0.1 4.1 0.1 - 0.1 0.1 0.1 2.7 0 0 3.6 0.1 4.2 2.9 2.7 2.4 1.4 2.8 2.9 2.5 3.2 3.1 0.1 0.1 1.5 4.1 3.6 0 0 0.2 0.1 0.1 0.1 1.4 0 1.8 2.0 0.1 0 0.2 0.2 0 0 0.7
0.3
3.4 3.2 0.5 0 0.4 2.2 0.2 0.1 0.1 0.4 0.2 0.1 0.4
[1] 4kfj.b 0.1 0.3 0.1 0 0.2 0.1 0.1 0 0.2 0.1 1.3 0.1 - 0.1 0.2 0.2 0.1 0 0 0 1.2 0.2 0.3 0.4 0.3 0.1 0.5 0.1 0.1 0.1 0.1 0 0.1 0.9 0.9 0.4 0.1 2.1 0.1 1.8 2.1 1.7 1.0 0.4 0.9 0.7 2.1 0.3 0.9 0.5 0.3 0.4 1.3 0.9
0
0.5 0.2 0.1 0.1 0.1 0.3 0.3 0.9 0.1 0.7 0.2 0.5
[1] 4m6l.a 0 0.1 0.2 0 0.3 0.3 0.2 0 0.1 0.1 0.6 0 - 0.1 0 0 0.3 0 0 0 0.3 0.1 0.4 0.2 0 0 0.2 0.1 0.1 0 0.2 0 0 0.4 0.4 0.6 0 0.9 0.1 0.9 0.9 0.7 2.1 0 0.4 0 1.3 0 0.7 0.5 0.3 0.2 1.8 1.2 0
0
0.3 0 0.2 0 0.2 0 0.6 0.1 0.7 0 0.1
[1] 4qhv.a 0.1 0.2 0 0.2 0.3 0 0 0 0.7 0.2 2.4 0.2 - 0 0.1 0.1 0.2 0.2 0.2 0.2 1.9 0.3 0.2 0.3 0.3 0.2 0.5 0.2 0.4 0.2 0.2 0 0.1 1.3 1.1 0.6 0.1 2.0 0.2 2.2 1.9 1.8 1.8 0.4 0.9 1.0 2.2 0.5 0.1 0.7 0.2 0.1 1.0 0.7 0.2 0.6
0
0 0 0 0.1 0 0.6 0 0 0.2 0.3
[1] 4qjc.a 0.5 0.2 3.2 3.7 3.2 3.4 3.2 0.2 0.7 0.8 4.7 0.9 - 0.9 0.1 0.1 3.6 0.2 0.3 3.9 0.7 4.6 3.5 6.0 5.0 3.2 5.8 3.7 4.0 3.9 3.7 0.4 0.5 3.9 5.6 5.2 0.5 0.3 0.6 0.3 0.3 0.2 1.3 0.2 3.9 2.4 0.2 0 0.9 0.9 0.9 0.8 3.2 2.8 3.5 5.8 1.6
0
1.2 1.9 0.3 0 1.4 1.1 1.2 0 0.4
[1] 5hpb.a 0.3 0.1 0 0.3 0.2 0.2 0.1 0 0.3 0.1 0.9 0.1 - 0.3 0.3 0.4 0 0.2 0.2 0.2 2.0 0.4 0.3 0.4 0.5 0.4 0.4 0.2 0.3 0.2 0.2 0.2 0.4 1.2 1.2 0.5 0.4 1.9 0.4 2.3 1.9 1.8 1.2 0.3 1.3 1.0 2.5 0.4 0.7 0.7 0.6 0.4 1.5 0.8 0.2 0.8 0.2 0.2
0
0.1 0.3 0.1 0.7 0.1 0.3 0.1 0.3
[1] 5hqz.a 0.1 0 0.1 0.3 0.1 0.1 0.1 0.2 0.3 0.1 1.3 0 - 0 0 0.1 0.2 0.3 0.2 0.3 1.9 0.5 0.4 0.4 0.4 0.5 0.4 0.2 0.3 0.2 0.2 0 0.4 1.5 0.9 0.6 0.3 1.9 0.6 2.0 2.1 1.4 1.0 0.3 1.2 0.8 2.3 0.5 0.9 1.0 0.9 0.5 2.3 1.5 0.3 0.8 0.5 0.1 0.2
0
0.3 0 0.5 0.1 0.8 0.1 0.3
[1] 5hsr.a 1.0 0.4 4.7 4.1 4.5 4.3 4.2 0.8 0.6 0.9 5.2 1.0 - 0.9 0 0.1 4.3 0.3 0.2 4.9 0.7 5.8 4.8 5.6 5.5 3.8 5.8 4.3 4.6 4.3 4.4 0.4 0.9 3.1 6.0 5.9 0.5 0.4 0.6 0.4 0.6 0.2 1.4 0.2 3.1 2.7 0.2 0 2.1 1.4 1.4 1.2 4.2 3.7 4.9 6.0 2.2 0.1 2.1 2.4
0.8
0 1.2 1.7 1.8 0.1 0.1
[1] 5hsu.a 0.2 0.3 0 0.4 0.1 0.1 0.1 0.2 0.5 0.2 0.3 0.1 - 0.3 0.1 0.4 0.3 0.3 0.3 0.3 2.2 0.4 0.5 0.5 0.4 0.4 0.6 0.3 0.2 0.2 0.3 0.2 0.5 1.6 1.3 0.8 0.3 2.3 0.6 2.6 2.3 2.0 1.4 0.4 1.3 0.9 2.5 0.6 1.2 1.2 1.0 0.8 2.9 2.0 0.3 1.0 0.5 0.3 0.3 0.1 0.3
0
0.6 0.2 1.0 0.1 0.2
[1] 5ht4.a 0.2 0.1 3.1 3.3 4.3 3.2 3.1 0.1 0.1 0.4 3.3 0.1 - 0.2 0.1 0.2 3.2 0.3 0.4 3.4 0.8 3.0 2.7 1.0 1.3 1.5 1.2 3.2 2.7 2.8 2.8 0.3 0.2 1.4 2.5 3.3 0.4 0.3 0.6 0.5 0.6 0.3 1.1 0.2 1.3 3.1 0.2 0.2 1.0 1.1 0.7 0.5 2.1 1.4 3.2 1.8 0.5 0.2 0.2 1.4 0.3 0
0
0.2 1.2 0 0.1
[1] 5ht5.a 0.2 0 0 0.2 0.1 0.2 0.1 0.1 0.4 0.2 1.3 0.2 - 0 0.2 0.3 0.1 0.2 0.2 0.2 2.0 0.3 0.4 0.4 0.5 0.4 0.4 0.2 0.4 0.2 0.2 0.1 0.3 1.2 1.1 0.5 0.3 2.0 0.4 2.4 1.9 1.8 1.2 0.5 1.1 1.1 2.4 0.5 0.9 0.9 0.7 0.3 2.0 1.5 0.2 0.8 0.2 0.2 0.1 0 0.2 0 0.6
0.1
0.7 0.2 0.4
[1] 5hui.a 0.2 0 0 0.3 0.2 0 0 0 0.3 0.1 0.1 0.1 - 0 0.1 0.1 0 0.1 0.1 0.3 1.9 0.5 0.3 0.3 0.4 0.2 0.4 0.3 0.3 0.2 0.3 0 0.1 1.3 1.0 0.6 0.3 1.8 0.3 1.6 1.7 1.4 1.1 0.3 1.2 1.0 2.4 0.5 0.1 0.7 0.4 0.1 1.3 0.5 0.3 0.8 0 0 0 0 0.1 0 0.5 0.1
0.1
0.1 0.3
[1] 5hvb.a 0.2 0.1 0 0.3 0.2 0.2 0.1 0.2 0.3 0.1 0.3 0.1 - 0.1 0.2 0.4 0.2 0.3 0.3 0.3 2.0 0.5 0.4 0.4 0.4 0.4 0.5 0.2 0.2 0.2 0.2 0.2 0.3 1.5 1.1 0.7 0.3 1.9 0.6 2.1 2.3 1.6 1.1 0.4 1.5 0.8 2.3 0.4 1.1 1.1 0.8 0.7 2.4 1.7 0.2 0.9 0.5 0.2 0.1 0.1 0.4 0 0.6 0.1 0.9
0.1
0.4
[1] 5hve.a 0.8 0.4 4.4 4.1 4.1 4.2 4.3 0.7 0.4 0.7 5.1 0.9 - 1.0 0.1 0.1 3.9 0.3 0.3 4.7 1.0 5.8 4.8 5.7 5.1 3.4 5.7 4.3 4.5 4.5 4.4 0.5 1.2 3.1 6.4 6.2 0.6 0.3 0.9 0.5 0.6 0.3 1.4 0.3 3.1 2.8 0.2 0 2.0 2.3 1.2 1.2 4.2 4.0 4.7 5.9 2.2 0.2 1.7 2.5 0.8 0 1.1 1.4 1.8 0.2
0
[Pocket-ligand steric clashes matrix]

Pocket clash dissimilarity (1 cluster)

Pockets (x) vs pockets (y) colored by ligand clash profile difference

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥1.
.9
.8
.7
.6
.5
.4
.3
.2
.1
.0
1boz.a
1dlr.a
1dls.a
1drf.a
1hfp.a
1hfq.a
1hfr.a
1kms.a
1kmv.a
1mvt.a
1ohk.a
1pd9.a
1pdb.a
1s3v.a
1s3w.a
1u71.a
1u72.a
2c2s.b
2c2t.b
2dhf.b
2w3a.a
2w3b.a
3eig.a
3f8y.a
3f8z.a
3f91.a
3fs6.a
3ghc.a
3ghv.a
3ghw.a
3gi2.a
3gyf.a
3l3r.a
3n0h.a
3ntz.a
3nu0.a
3nxo.a
3nxr.a
3nxt.a
3nxv.a
3nxx.a
3nxy.a
3nzd.a
3oaf.a
3s3v.a
3s7a.a
4ddr.a
4g95.a
4kak.b
4kbn.a
4kbn.b
4kd7.a
4keb.a
4kfj.a
4kfj.b
4m6l.a
4qhv.a
4qjc.a
5hpb.a
5hqz.a
5hsr.a
5hsu.a
5ht4.a
5ht5.a
5hui.a
5hvb.a
5hve.a
[1] 1boz.a
0
.18 .16 .14 .09 .12 .14 .19 .17 .16 .16 .09 .12 .16 .13 .14 .15 .19 .20 .14 .13 .08 .24 .16 .14 .14 .13 .17 .16 .20 .17 .18 .14 .14 .13 .18 .11 .16 .14 .17 .14 .17 .19 .17 .12 .16 .18 .16 .17 .23 .20 .20 .20 .17 .17 .11 .18 .16 .15 .16 .17 .16 .20 .16 .15 .16 .20
[1] 1dlr.a .18
0
.15 .20 .22 .19 .17 .12 .17 .22 .20 .17 .15 .22 .10 .11 .17 .17 .17 .18 .14 .14 .30 .19 .19 .19 .18 .17 .19 .15 .17 .14 .16 .22 .19 .18 .11 .12 .12 .15 .12 .17 .09 .16 .18 .22 .10 .13 .12 .14 .11 .11 .19 .15 .17 .20 .13 .13 .16 .15 .14 .18 .18 .14 .17 .18 .14
[1] 1dls.a .16 .15
0
.09 .09 .09 .06 .07 .06 .19 .07 .15 .17 .20 .14 .15 .05 .13 .12 .09 .17 .10 .17 .10 .09 .07 .07 .09 .08 .10 .09 .07 .08 .11 .09 .10 .15 .17 .18 .21 .15 .22 .18 .11 .15 .15 .18 .20 .16 .19 .20 .21 .12 .12 .08 .10 .11 .19 .08 .07 .19 .09 .11 .07 .06 .05 .20
[1] 1drf.a .14 .20 .09
0
.10 .13 .06 .11 .09 .19 .11 .13 .17 .17 .14 .15 .06 .12 .12 .06 .14 .12 .16 .08 .07 .06 .07 .09 .06 .10 .08 .09 .09 .09 .11 .09 .12 .16 .16 .18 .14 .19 .20 .10 .12 .12 .20 .18 .17 .17 .21 .20 .11 .11 .09 .07 .12 .17 .09 .09 .19 .09 .12 .09 .07 .08 .22
[1] 1hfp.a .09 .22 .09 .10
0
.04 .07 .14 .11 .21 .11 .15 .18 .22 .16 .19 .08 .16 .15 .10 .18 .11 .20 .10 .10 .08 .08 .10 .08 .12 .09 .12 .11 .12 .08 .12 .17 .20 .20 .22 .18 .23 .21 .13 .16 .12 .21 .21 .20 .22 .23 .26 .16 .15 .10 .09 .15 .19 .10 .10 .20 .11 .15 .10 .10 .09 .23
[1] 1hfq.a .12 .19 .09 .13 .04
0
.08 .13 .10 .22 .12 .16 .19 .23 .18 .20 .10 .16 .15 .12 .20 .12 .22 .12 .12 .11 .11 .13 .11 .10 .11 .09 .10 .13 .10 .14 .19 .23 .22 .25 .19 .25 .18 .14 .18 .14 .18 .22 .19 .19 .20 .22 .16 .15 .10 .11 .13 .21 .12 .10 .21 .12 .16 .09 .11 .11 .23
[1] 1hfr.a .14 .17 .06 .06 .07 .08
0
.08 .06 .18 .08 .12 .14 .19 .11 .13 .03 .10 .09 .05 .13 .08 .17 .05 .06 .04 .05 .06 .04 .08 .04 .06 .08 .09 .08 .07 .12 .15 .16 .18 .12 .18 .16 .08 .12 .12 .15 .15 .15 .17 .18 .20 .10 .10 .04 .08 .11 .14 .05 .05 .15 .05 .09 .04 .04 .05 .18
[1] 1kms.a .19 .12 .07 .11 .14 .13 .08
0
.07 .21 .10 .16 .17 .21 .12 .12 .08 .09 .09 .08 .13 .13 .22 .10 .12 .10 .10 .11 .10 .12 .11 .06 .08 .13 .13 .12 .12 .14 .14 .16 .11 .18 .14 .08 .16 .16 .13 .15 .11 .14 .16 .15 .09 .09 .10 .11 .10 .14 .10 .10 .15 .10 .09 .07 .08 .09 .16
[1] 1kmv.a .17 .17 .06 .09 .11 .10 .06 .07
0
.17 .09 .13 .16 .19 .14 .13 .06 .13 .12 .06 .16 .11 .17 .06 .10 .06 .07 .09 .06 .10 .08 .05 .08 .10 .11 .11 .14 .19 .18 .20 .14 .19 .14 .07 .12 .12 .14 .16 .14 .19 .20 .20 .12 .12 .08 .10 .10 .16 .09 .06 .14 .06 .10 .05 .08 .04 .16
[1] 1mvt.a .16 .22 .19 .19 .21 .22 .18 .21 .17
0
.17 .11 .17 .04 .14 .14 .18 .22 .23 .17 .16 .12 .22 .18 .19 .16 .17 .22 .19 .24 .20 .20 .19 .18 .20 .23 .15 .19 .18 .21 .15 .19 .18 .19 .15 .19 .17 .18 .19 .27 .24 .23 .23 .20 .21 .18 .24 .16 .19 .18 .15 .16 .20 .19 .19 .16 .18
[1] 1ohk.a .16 .20 .07 .11 .11 .12 .08 .10 .09 .17
0
.13 .15 .19 .15 .18 .09 .11 .12 .10 .14 .11 .14 .11 .09 .09 .08 .10 .11 .13 .11 .10 .10 .11 .11 .11 .16 .19 .17 .20 .17 .23 .19 .11 .16 .14 .19 .20 .15 .18 .19 .20 .11 .13 .09 .10 .12 .20 .07 .08 .18 .09 .11 .09 .07 .07 .20
[1] 1pd9.a .09 .17 .15 .13 .15 .16 .12 .16 .13 .11 .13
0
.08 .11 .10 .10 .12 .15 .16 .13 .11 .07 .20 .13 .13 .13 .13 .14 .15 .18 .13 .16 .13 .13 .14 .17 .09 .13 .11 .14 .11 .14 .13 .16 .11 .13 .12 .13 .13 .20 .18 .17 .17 .14 .14 .11 .17 .13 .13 .13 .10 .12 .17 .13 .13 .13 .13
[1] 1pdb.a .12 .15 .17 .17 .18 .19 .14 .17 .16 .17 .15 .08
0
.17 .12 .14 .14 .17 .18 .15 .12 .10 .22 .15 .11 .15 .15 .12 .17 .20 .14 .17 .13 .16 .13 .12 .11 .12 .10 .10 .13 .12 .14 .17 .12 .15 .13 .12 .15 .21 .18 .18 .18 .16 .13 .15 .13 .13 .12 .13 .13 .15 .19 .13 .13 .15 .14
[1] 1s3v.a .16 .22 .20 .17 .22 .23 .19 .21 .19 .04 .19 .11 .17
0
.15 .15 .18 .22 .24 .17 .16 .13 .22 .19 .20 .17 .18 .22 .20 .24 .21 .20 .19 .18 .21 .23 .16 .19 .18 .21 .15 .19 .19 .20 .15 .20 .18 .19 .19 .27 .24 .22 .23 .21 .21 .19 .23 .17 .20 .20 .16 .18 .21 .20 .19 .18 .19
[1] 1s3w.a .13 .10 .14 .14 .16 .18 .11 .12 .14 .14 .15 .10 .12 .15
0
.07 .12 .12 .12 .12 .06 .08 .25 .13 .12 .13 .12 .12 .12 .17 .12 .13 .13 .16 .14 .13 .04 .06 .07 .09 .07 .10 .08 .11 .12 .18 .08 .08 .08 .17 .12 .13 .13 .10 .12 .15 .16 .06 .11 .11 .07 .12 .11 .10 .11 .12 .10
[1] 1u71.a .14 .11 .15 .15 .19 .20 .13 .12 .13 .14 .18 .10 .14 .15 .07
0
.13 .14 .14 .12 .10 .10 .24 .12 .16 .13 .14 .16 .13 .19 .15 .14 .16 .15 .18 .18 .07 .10 .10 .13 .08 .12 .12 .12 .12 .18 .10 .11 .11 .19 .17 .15 .16 .11 .16 .16 .19 .09 .15 .14 .09 .12 .13 .14 .14 .13 .12
[1] 1u72.a .15 .17 .05 .06 .08 .10 .03 .08 .06 .18 .09 .12 .14 .18 .12 .13
0
.11 .11 .06 .14 .09 .16 .07 .08 .06 .06 .06 .05 .09 .06 .06 .09 .10 .08 .08 .13 .16 .15 .18 .14 .19 .17 .09 .14 .13 .17 .17 .14 .17 .19 .20 .10 .11 .06 .09 .11 .17 .07 .06 .16 .06 .09 .07 .04 .05 .19
[1] 2c2s.b .19 .17 .13 .12 .16 .16 .10 .09 .13 .22 .11 .15 .17 .22 .12 .14 .11
0
.01 .11 .10 .16 .21 .14 .10 .12 .12 .11 .12 .15 .13 .11 .12 .13 .16 .12 .11 .13 .09 .12 .13 .18 .16 .10 .16 .16 .16 .18 .08 .07 .11 .12 .03 .06 .10 .11 .12 .17 .09 .12 .17 .12 .12 .11 .08 .13 .18
[1] 2c2t.b .20 .17 .12 .12 .15 .15 .09 .09 .12 .23 .12 .16 .18 .24 .12 .14 .11 .01
0
.11 .11 .15 .22 .13 .10 .11 .12 .11 .12 .14 .12 .10 .12 .14 .15 .12 .12 .13 .10 .12 .13 .18 .16 .10 .16 .18 .16 .17 .07 .08 .11 .12 .03 .06 .10 .12 .12 .16 .09 .11 .17 .13 .12 .10 .08 .12 .18
[1] 2dhf.b .14 .18 .09 .06 .10 .12 .05 .08 .06 .17 .10 .13 .15 .17 .12 .12 .06 .11 .11
0
.11 .10 .17 .06 .07 .04 .05 .08 .05 .10 .06 .06 .08 .07 .10 .09 .10 .14 .14 .16 .10 .16 .17 .06 .09 .12 .16 .14 .14 .17 .19 .19 .10 .10 .07 .07 .10 .14 .08 .07 .15 .07 .09 .07 .07 .06 .18
[1] 2w3a.a .13 .14 .17 .14 .18 .20 .13 .13 .16 .16 .14 .11 .12 .16 .06 .10 .14 .10 .11 .11
0
.09 .24 .15 .12 .12 .13 .13 .14 .18 .15 .15 .16 .14 .17 .14 .05 .06 .04 .08 .06 .10 .12 .12 .10 .20 .12 .11 .06 .13 .10 .11 .10 .09 .14 .14 .17 .10 .12 .16 .11 .15 .13 .14 .12 .15 .14
[1] 2w3b.a .08 .14 .10 .12 .11 .12 .08 .13 .11 .12 .11 .07 .10 .13 .08 .10 .09 .16 .15 .10 .09
0
.21 .10 .10 .09 .09 .11 .10 .13 .11 .12 .11 .12 .10 .12 .09 .12 .12 .14 .09 .15 .13 .13 .09 .15 .12 .12 .11 .20 .16 .16 .16 .12 .10 .11 .16 .12 .10 .10 .11 .10 .14 .09 .09 .09 .15
[1] 3eig.a .24 .30 .17 .16 .20 .22 .17 .22 .17 .22 .14 .20 .22 .22 .25 .24 .16 .21 .22 .17 .24 .21
0
.20 .17 .17 .18 .18 .18 .22 .18 .20 .19 .21 .19 .19 .25 .27 .27 .29 .27 .31 .28 .22 .24 .21 .29 .30 .26 .27 .29 .30 .21 .21 .18 .20 .21 .29 .18 .18 .28 .20 .22 .19 .16 .17 .29
[1] 3f8y.a .16 .19 .10 .08 .10 .12 .05 .10 .06 .18 .11 .13 .15 .19 .13 .12 .07 .14 .13 .06 .15 .10 .20
0
.07 .04 .04 .07 .04 .10 .07 .08 .08 .06 .09 .09 .12 .16 .16 .17 .11 .15 .16 .05 .10 .11 .13 .11 .18 .20 .22 .22 .14 .14 .09 .09 .12 .14 .08 .06 .12 .03 .09 .06 .07 .05 .15
[1] 3f8z.a .14 .19 .09 .07 .10 .12 .06 .12 .10 .19 .09 .13 .11 .20 .12 .16 .08 .10 .10 .07 .12 .10 .17 .07
0
.04 .05 .05 .07 .10 .06 .10 .06 .07 .07 .06 .11 .13 .12 .14 .12 .18 .18 .10 .11 .11 .18 .16 .15 .16 .18 .20 .10 .10 .05 .07 .09 .16 .05 .06 .17 .08 .12 .07 .04 .07 .20
[1] 3f91.a .14 .19 .07 .06 .08 .11 .04 .10 .06 .16 .09 .13 .15 .17 .13 .13 .06 .12 .11 .04 .12 .09 .17 .04 .04
0
.03 .07 .04 .08 .06 .07 .07 .05 .08 .08 .12 .15 .15 .17 .11 .17 .16 .07 .09 .10 .17 .15 .16 .18 .20 .21 .11 .11 .07 .07 .12 .15 .07 .06 .16 .05 .09 .07 .06 .04 .18
[1] 3fs6.a .13 .18 .07 .07 .08 .11 .05 .10 .07 .17 .08 .13 .15 .18 .12 .14 .06 .12 .12 .05 .13 .09 .18 .04 .05 .03
0
.06 .04 .09 .06 .07 .07 .05 .07 .07 .11 .15 .14 .17 .11 .19 .16 .07 .09 .11 .17 .14 .16 .19 .20 .21 .13 .13 .07 .07 .11 .14 .06 .04 .15 .05 .08 .06 .06 .04 .18
[1] 3ghc.a .17 .17 .09 .09 .10 .13 .06 .11 .09 .22 .10 .14 .12 .22 .12 .16 .06 .11 .11 .08 .13 .11 .18 .07 .05 .07 .06
0
.05 .10 .02 .09 .09 .11 .05 .02 .12 .12 .13 .13 .13 .16 .16 .10 .15 .11 .16 .13 .16 .18 .19 .21 .12 .12 .05 .10 .09 .13 .05 .05 .16 .07 .11 .06 .05 .07 .17
[1] 3ghv.a .16 .19 .08 .06 .08 .11 .04 .10 .06 .19 .11 .15 .17 .20 .12 .13 .05 .12 .12 .05 .14 .10 .18 .04 .07 .04 .04 .05
0
.09 .04 .07 .09 .08 .09 .06 .12 .15 .16 .18 .12 .17 .15 .07 .12 .12 .15 .14 .17 .18 .19 .22 .12 .12 .07 .10 .13 .15 .07 .06 .14 .05 .09 .07 .06 .05 .17
[1] 3ghw.a .20 .15 .10 .10 .12 .10 .08 .12 .10 .24 .13 .18 .20 .24 .17 .19 .09 .15 .14 .10 .18 .13 .22 .10 .10 .08 .09 .10 .09
0
.09 .08 .10 .13 .12 .12 .17 .20 .20 .22 .16 .23 .16 .11 .16 .17 .17 .20 .18 .13 .15 .16 .15 .14 .09 .13 .10 .19 .10 .09 .21 .11 .14 .08 .09 .09 .22
[1] 3gi2.a .17 .17 .09 .08 .09 .11 .04 .11 .08 .20 .11 .13 .14 .21 .12 .15 .06 .13 .12 .06 .15 .11 .18 .07 .06 .06 .06 .02 .04 .09
0
.08 .09 .11 .06 .04 .12 .14 .15 .15 .13 .16 .15 .09 .15 .10 .14 .13 .17 .19 .20 .23 .13 .12 .05 .10 .10 .12 .06 .05 .14 .07 .10 .05 .07 .07 .16
[1] 3gyf.a .18 .14 .07 .09 .12 .09 .06 .06 .05 .20 .10 .16 .17 .20 .13 .14 .06 .11 .10 .06 .15 .12 .20 .08 .10 .07 .07 .09 .07 .08 .08
0
.08 .10 .11 .10 .12 .16 .15 .18 .11 .18 .13 .08 .13 .13 .14 .17 .12 .15 .17 .17 .10 .10 .08 .10 .09 .16 .09 .07 .17 .07 .11 .06 .06 .07 .17
[1] 3l3r.a .14 .16 .08 .09 .11 .10 .08 .08 .08 .19 .10 .13 .13 .19 .13 .16 .09 .12 .12 .08 .16 .11 .19 .08 .06 .07 .07 .09 .09 .10 .09 .08
0
.08 .09 .10 .11 .16 .15 .16 .13 .18 .16 .09 .11 .11 .15 .16 .16 .17 .19 .18 .13 .13 .08 .08 .07 .15 .08 .06 .18 .10 .13 .05 .08 .08 .19
[1] 3n0h.a .14 .22 .11 .09 .12 .13 .09 .13 .10 .18 .11 .13 .16 .18 .16 .15 .10 .13 .14 .07 .14 .12 .21 .06 .07 .05 .05 .11 .08 .13 .11 .10 .08
0
.10 .12 .12 .16 .15 .17 .12 .16 .18 .07 .06 .10 .18 .14 .19 .20 .22 .23 .14 .15 .11 .06 .13 .17 .10 .09 .16 .07 .11 .10 .10 .08 .19
[1] 3ntz.a .13 .19 .09 .11 .08 .10 .08 .13 .11 .20 .11 .14 .13 .21 .14 .18 .08 .16 .15 .10 .17 .10 .19 .09 .07 .08 .07 .05 .09 .12 .06 .11 .09 .10
0
.07 .14 .15 .16 .17 .16 .19 .17 .12 .15 .08 .18 .16 .20 .22 .23 .24 .16 .16 .07 .09 .11 .16 .08 .06 .17 .09 .12 .07 .08 .08 .19
[1] 3nu0.a .18 .18 .10 .09 .12 .14 .07 .12 .11 .23 .11 .17 .12 .23 .13 .18 .08 .12 .12 .09 .14 .12 .19 .09 .06 .08 .07 .02 .06 .12 .04 .10 .10 .12 .07
0
.13 .13 .14 .13 .14 .15 .18 .11 .16 .14 .18 .15 .17 .18 .19 .22 .13 .13 .06 .12 .10 .14 .06 .07 .18 .10 .12 .08 .06 .09 .19
[1] 3nxo.a .11 .11 .15 .12 .17 .19 .12 .12 .14 .15 .16 .09 .11 .16 .04 .07 .13 .11 .12 .10 .05 .09 .25 .12 .11 .12 .11 .12 .12 .17 .12 .12 .11 .12 .14 .13
0
.06 .04 .07 .04 .09 .10 .11 .08 .16 .10 .09 .08 .16 .12 .13 .13 .11 .13 .12 .14 .07 .11 .12 .09 .12 .13 .11 .11 .13 .12
[1] 3nxr.a .16 .12 .17 .16 .20 .23 .15 .14 .19 .19 .19 .13 .12 .19 .06 .10 .16 .13 .13 .14 .06 .12 .27 .16 .13 .15 .15 .12 .15 .20 .14 .16 .16 .16 .15 .13 .06
0
.05 .06 .07 .09 .11 .14 .12 .19 .11 .09 .09 .17 .14 .13 .13 .11 .14 .17 .16 .07 .13 .14 .10 .17 .14 .14 .13 .17 .12
[1] 3nxt.a .14 .12 .18 .16 .20 .22 .16 .14 .18 .18 .17 .11 .10 .18 .07 .10 .15 .09 .10 .14 .04 .12 .27 .16 .12 .15 .14 .13 .16 .20 .15 .15 .15 .15 .16 .14 .04 .05
0
.04 .07 .10 .11 .13 .11 .18 .11 .09 .07 .13 .10 .11 .11 .10 .15 .15 .14 .10 .12 .15 .10 .15 .15 .14 .12 .16 .12
[1] 3nxv.a .17 .15 .21 .18 .22 .25 .18 .16 .20 .21 .20 .14 .10 .21 .09 .13 .18 .12 .12 .16 .08 .14 .29 .17 .14 .17 .17 .13 .18 .22 .15 .18 .16 .17 .17 .13 .07 .06 .04
0
.09 .08 .14 .16 .13 .20 .14 .11 .08 .15 .12 .13 .14 .11 .16 .18 .15 .09 .15 .17 .14 .19 .18 .16 .14 .19 .15
[1] 3nxx.a .14 .12 .15 .14 .18 .19 .12 .11 .14 .15 .17 .11 .13 .15 .07 .08 .14 .13 .13 .10 .06 .09 .27 .11 .12 .11 .11 .13 .12 .16 .13 .11 .13 .12 .16 .14 .04 .07 .07 .09
0
.10 .09 .10 .08 .18 .10 .08 .09 .16 .13 .14 .14 .10 .14 .14 .16 .08 .13 .13 .09 .12 .13 .12 .12 .12 .10
[1] 3nxy.a .17 .17 .22 .19 .23 .25 .18 .18 .19 .19 .23 .14 .12 .19 .10 .12 .19 .18 .18 .16 .10 .15 .31 .15 .18 .17 .19 .16 .17 .23 .16 .18 .18 .16 .19 .15 .09 .09 .10 .08 .10
0
.12 .14 .13 .17 .10 .06 .15 .22 .18 .19 .19 .15 .18 .18 .19 .09 .18 .18 .09 .16 .17 .17 .19 .19 .11
[1] 3nzd.a .19 .09 .18 .20 .21 .18 .16 .14 .14 .18 .19 .13 .14 .19 .08 .12 .17 .16 .16 .17 .12 .13 .28 .16 .18 .16 .16 .16 .15 .16 .15 .13 .16 .18 .17 .18 .10 .11 .11 .14 .09 .12
0
.12 .15 .18 .04 .08 .11 .16 .12 .13 .17 .14 .17 .19 .15 .11 .15 .13 .07 .13 .14 .13 .17 .15 .07
[1] 3oaf.a .17 .16 .11 .10 .13 .14 .08 .08 .07 .19 .11 .16 .17 .20 .11 .12 .09 .10 .10 .06 .12 .13 .22 .05 .10 .07 .07 .10 .07 .11 .09 .08 .09 .07 .12 .11 .11 .14 .13 .16 .10 .14 .12
0
.11 .12 .11 .09 .14 .17 .18 .19 .10 .11 .10 .11 .13 .13 .09 .08 .11 .06 .07 .09 .09 .07 .13
[1] 3s3v.a .12 .18 .15 .12 .16 .18 .12 .16 .12 .15 .16 .11 .12 .15 .12 .12 .14 .16 .16 .09 .10 .09 .24 .10 .11 .09 .09 .15 .12 .16 .15 .13 .11 .06 .15 .16 .08 .12 .11 .13 .08 .13 .15 .11
0
.15 .14 .11 .13 .20 .19 .18 .17 .14 .14 .11 .16 .13 .13 .13 .13 .12 .15 .13 .13 .11 .16
[1] 3s7a.a .16 .22 .15 .12 .12 .14 .12 .16 .12 .19 .14 .13 .15 .20 .18 .18 .13 .16 .18 .12 .20 .15 .21 .11 .11 .10 .11 .11 .12 .17 .10 .13 .11 .10 .08 .14 .16 .19 .18 .20 .18 .17 .18 .12 .15
0
.18 .17 .23 .23 .27 .26 .17 .19 .13 .08 .14 .18 .12 .10 .17 .10 .15 .11 .14 .11 .16
[1] 4ddr.a .18 .10 .18 .20 .21 .18 .15 .13 .14 .17 .19 .12 .13 .18 .08 .10 .17 .16 .16 .16 .12 .12 .29 .13 .18 .17 .17 .16 .15 .17 .14 .14 .15 .18 .18 .18 .10 .11 .11 .14 .10 .10 .04 .11 .14 .18
0
.06 .11 .18 .13 .14 .17 .13 .15 .19 .17 .09 .15 .13 .04 .12 .13 .12 .17 .15 .06
[1] 4g95.a .16 .13 .20 .18 .21 .22 .15 .15 .16 .18 .20 .13 .12 .19 .08 .11 .17 .18 .17 .14 .11 .12 .30 .11 .16 .15 .14 .13 .14 .20 .13 .17 .16 .14 .16 .15 .09 .09 .09 .11 .08 .06 .08 .09 .11 .17 .06
0
.14 .22 .17 .18 .18 .15 .16 .17 .18 .07 .15 .14 .06 .12 .14 .14 .17 .15 .07
[1] 4kak.b .17 .12 .16 .17 .20 .19 .15 .11 .14 .19 .15 .13 .15 .19 .08 .11 .14 .08 .07 .14 .06 .11 .26 .18 .15 .16 .16 .16 .17 .18 .17 .12 .16 .19 .20 .17 .08 .09 .07 .08 .09 .15 .11 .14 .13 .23 .11 .14
0
.11 .07 .06 .08 .06 .15 .17 .14 .12 .15 .16 .13 .17 .15 .14 .12 .16 .14
[1] 4kbn.a .23 .14 .19 .17 .22 .19 .17 .14 .19 .27 .18 .20 .21 .27 .17 .19 .17 .07 .08 .17 .13 .20 .27 .20 .16 .18 .19 .18 .18 .13 .19 .15 .17 .20 .22 .18 .16 .17 .13 .15 .16 .22 .16 .17 .20 .23 .18 .22 .11
0
.05 .07 .09 .09 .17 .17 .14 .21 .16 .19 .21 .19 .19 .17 .15 .20 .23
[1] 4kbn.b .20 .11 .20 .21 .23 .20 .18 .16 .20 .24 .19 .18 .18 .24 .12 .17 .19 .11 .11 .19 .10 .16 .29 .22 .18 .20 .20 .19 .19 .15 .20 .17 .19 .22 .23 .19 .12 .14 .10 .12 .13 .18 .12 .18 .19 .27 .13 .17 .07 .05
0
.06 .13 .12 .17 .21 .16 .17 .17 .20 .17 .20 .20 .18 .17 .21 .18
[1] 4kd7.a .20 .11 .21 .20 .26 .22 .20 .15 .20 .23 .20 .17 .18 .22 .13 .15 .20 .12 .12 .19 .11 .16 .30 .22 .20 .21 .21 .21 .22 .16 .23 .17 .18 .23 .24 .22 .13 .13 .11 .13 .14 .19 .13 .19 .18 .26 .14 .18 .06 .07 .06
0
.12 .11 .20 .21 .15 .16 .20 .21 .17 .22 .20 .19 .18 .21 .19
[1] 4keb.a .20 .19 .12 .11 .16 .16 .10 .09 .12 .23 .11 .17 .18 .23 .13 .16 .10 .03 .03 .10 .10 .16 .21 .14 .10 .11 .13 .12 .12 .15 .13 .10 .13 .14 .16 .13 .13 .13 .11 .14 .14 .19 .17 .10 .17 .17 .17 .18 .08 .09 .13 .12
0
.05 .11 .11 .12 .17 .10 .13 .17 .13 .10 .11 .09 .12 .19
[1] 4kfj.a .17 .15 .12 .11 .15 .15 .10 .09 .12 .20 .13 .14 .16 .21 .10 .11 .11 .06 .06 .10 .09 .12 .21 .14 .10 .11 .13 .12 .12 .14 .12 .10 .13 .15 .16 .13 .11 .11 .10 .11 .10 .15 .14 .11 .14 .19 .13 .15 .06 .09 .12 .11 .05
0
.10 .13 .13 .13 .11 .12 .14 .14 .12 .11 .09 .12 .16
[1] 4kfj.b .17 .17 .08 .09 .10 .10 .04 .10 .08 .21 .09 .14 .13 .21 .12 .16 .06 .10 .10 .07 .14 .10 .18 .09 .05 .07 .07 .05 .07 .09 .05 .08 .08 .11 .07 .06 .13 .14 .15 .16 .14 .18 .17 .10 .14 .13 .15 .16 .15 .17 .17 .20 .11 .10
0
.09 .09 .15 .05 .04 .17 .08 .12 .04 .06 .07 .18
[1] 4m6l.a .11 .20 .10 .07 .09 .11 .08 .11 .10 .18 .10 .11 .15 .19 .15 .16 .09 .11 .12 .07 .14 .11 .20 .09 .07 .07 .07 .10 .10 .13 .10 .10 .08 .06 .09 .12 .12 .17 .15 .18 .14 .18 .19 .11 .11 .08 .19 .17 .17 .17 .21 .21 .11 .13 .09
0
.12 .18 .09 .09 .18 .10 .13 .09 .10 .10 .21
[1] 4qhv.a .18 .13 .11 .12 .15 .13 .11 .10 .10 .24 .12 .17 .13 .23 .16 .19 .11 .12 .12 .10 .17 .16 .21 .12 .09 .12 .11 .09 .13 .10 .10 .09 .07 .13 .11 .10 .14 .16 .14 .15 .16 .19 .15 .13 .16 .14 .17 .18 .14 .14 .16 .15 .12 .13 .09 .12
0
.18 .10 .10 .20 .13 .17 .08 .08 .12 .21
[1] 4qjc.a .16 .13 .19 .17 .19 .21 .14 .14 .16 .16 .20 .13 .13 .17 .06 .09 .17 .17 .16 .14 .10 .12 .29 .14 .16 .15 .14 .13 .15 .19 .12 .16 .15 .17 .16 .14 .07 .07 .10 .09 .08 .09 .11 .13 .13 .18 .09 .07 .12 .21 .17 .16 .17 .13 .15 .18 .18
0
.14 .13 .08 .14 .13 .13 .16 .15 .10
[1] 5hpb.a .15 .16 .08 .09 .10 .12 .05 .10 .09 .19 .07 .13 .12 .20 .11 .15 .07 .09 .09 .08 .12 .10 .18 .08 .05 .07 .06 .05 .07 .10 .06 .09 .08 .10 .08 .06 .11 .13 .12 .15 .13 .18 .15 .09 .13 .12 .15 .15 .15 .16 .17 .20 .10 .11 .05 .09 .10 .14
0
.05 .14 .06 .09 .04 .04 .06 .17
[1] 5hqz.a .16 .15 .07 .09 .10 .10 .05 .10 .06 .18 .08 .13 .13 .20 .11 .14 .06 .12 .11 .07 .16 .10 .18 .06 .06 .06 .04 .05 .06 .09 .05 .07 .06 .09 .06 .07 .12 .14 .15 .17 .13 .18 .13 .08 .13 .10 .13 .14 .16 .19 .20 .21 .13 .12 .04 .09 .10 .13 .05
0
.14 .05 .09 .03 .07 .03 .15
[1] 5hsr.a .17 .14 .19 .19 .20 .21 .15 .15 .14 .15 .18 .10 .13 .16 .07 .09 .16 .17 .17 .15 .11 .11 .28 .12 .17 .16 .15 .16 .14 .21 .14 .17 .18 .16 .17 .18 .09 .10 .10 .14 .09 .09 .07 .11 .13 .17 .04 .06 .13 .21 .17 .17 .17 .14 .17 .18 .20 .08 .14 .14
0
.10 .11 .14 .17 .14 .03
[1] 5hsu.a .16 .18 .09 .09 .11 .12 .05 .10 .06 .16 .09 .12 .15 .18 .12 .12 .06 .12 .13 .07 .15 .10 .20 .03 .08 .05 .05 .07 .05 .11 .07 .07 .10 .07 .09 .10 .12 .17 .15 .19 .12 .16 .13 .06 .12 .10 .12 .12 .17 .19 .20 .22 .13 .14 .08 .10 .13 .14 .06 .05 .10
0
.08 .06 .07 .04 .13
[1] 5ht4.a .20 .18 .11 .12 .15 .16 .09 .09 .10 .20 .11 .17 .19 .21 .11 .13 .09 .12 .12 .09 .13 .14 .22 .09 .12 .09 .08 .11 .09 .14 .10 .11 .13 .11 .12 .12 .13 .14 .15 .18 .13 .17 .14 .07 .15 .15 .13 .14 .15 .19 .20 .20 .10 .12 .12 .13 .17 .13 .09 .09 .11 .08
0
.10 .10 .07 .14
[1] 5ht5.a .16 .14 .07 .09 .10 .09 .04 .07 .05 .19 .09 .13 .13 .20 .10 .14 .07 .11 .10 .07 .14 .09 .19 .06 .07 .07 .06 .06 .07 .08 .05 .06 .05 .10 .07 .08 .11 .14 .14 .16 .12 .17 .13 .09 .13 .11 .12 .14 .14 .17 .18 .19 .11 .11 .04 .09 .08 .13 .04 .03 .14 .06 .10
0
.06 .05 .15
[1] 5hui.a .15 .17 .06 .07 .10 .11 .04 .08 .08 .19 .07 .13 .13 .19 .11 .14 .04 .08 .08 .07 .12 .09 .16 .07 .04 .06 .06 .05 .06 .09 .07 .06 .08 .10 .08 .06 .11 .13 .12 .14 .12 .19 .17 .09 .13 .14 .17 .17 .12 .15 .17 .18 .09 .09 .06 .10 .08 .16 .04 .07 .17 .07 .10 .06
0
.06 .19
[1] 5hvb.a .16 .18 .05 .08 .09 .11 .05 .09 .04 .16 .07 .13 .15 .18 .12 .13 .05 .13 .12 .06 .15 .09 .17 .05 .07 .04 .04 .07 .05 .09 .07 .07 .08 .08 .08 .09 .13 .17 .16 .19 .12 .19 .15 .07 .11 .11 .15 .15 .16 .20 .21 .21 .12 .12 .07 .10 .12 .15 .06 .03 .14 .04 .07 .05 .06
0
.16
[1] 5hve.a .20 .14 .20 .22 .23 .23 .18 .16 .16 .18 .20 .13 .14 .19 .10 .12 .19 .18 .18 .18 .14 .15 .29 .15 .20 .18 .18 .17 .17 .22 .16 .17 .19 .19 .19 .19 .12 .12 .12 .15 .10 .11 .07 .13 .16 .16 .06 .07 .14 .23 .18 .19 .19 .16 .18 .21 .21 .10 .17 .15 .03 .13 .14 .15 .19 .16
0
[Pocket clash dissimilarity matrix]

Site backbone RMSD (median 1.2 Å)

Pockets (x) vs pockets (y) colored by RMSD of site residue backbone atoms

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥10 Å
9 Å
8 Å
7 Å
6 Å
5 Å
4 Å
3 Å
2 Å
1 Å
0 Å
1boz.a
1dlr.a
1dls.a
1drf.a
1hfp.a
1hfq.a
1hfr.a
1kms.a
1kmv.a
1mvt.a
1ohk.a
1pd9.a
1pdb.a
1s3v.a
1s3w.a
1u71.a
1u72.a
2c2s.b
2c2t.b
2dhf.b
2w3a.a
2w3b.a
3eig.a
3f8y.a
3f8z.a
3f91.a
3fs6.a
3ghc.a
3ghv.a
3ghw.a
3gi2.a
3gyf.a
3l3r.a
3n0h.a
3ntz.a
3nu0.a
3nxo.a
3nxr.a
3nxt.a
3nxv.a
3nxx.a
3nxy.a
3nzd.a
3oaf.a
3s3v.a
3s7a.a
4ddr.a
4g95.a
4kak.b
4kbn.a
4kbn.b
4kd7.a
4keb.a
4kfj.a
4kfj.b
4m6l.a
4qhv.a
4qjc.a
5hpb.a
5hqz.a
5hsr.a
5hsu.a
5ht4.a
5ht5.a
5hui.a
5hvb.a
5hve.a
[1] 1boz.a
0
0.3 0.3 0.3 0.2 0.3 0.2 0.5 0.6 0.5 0.7 0.3 0.5 0.5 0.2 0.4 0.3 0.5 0.4 0.3 0.5 0.3 1.0 0.4 0.3 0.3 0.3 0.4 0.4 0.3 0.4 0.3 0.3 0.4 0.3 0.4 0.4 0.3 0.3 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.5 0.4 0.4 0.6 0.4 0.4 0.4 0.3 0.4 0.3 0.3 0.4 0.3 0.3 0.5 0.4 0.4 0.3 0.3 0.4 0.5
[1] 1dlr.a 0.3
0
0.3 0.4 0.3 0.3 0.3 0.5 0.5 0.6 0.7 0.3 0.5 0.6 0.2 0.4 0.3 0.6 0.5 0.4 0.5 0.4 1.0 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.3 0.4 0.5 0.4 0.4 0.5 0.4 0.5 0.6 0.4 0.4 0.4 0.4 0.5 0.5 0.4 0.5 0.5 0.7 0.5 0.6 0.5 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.5 0.4 0.4 0.4 0.4 0.4 0.5
[1] 1dls.a 0.3 0.3
0
0.4 0.3 0.3 0.2 0.6 0.5 0.6 0.6 0.4 0.6 0.6 0.3 0.5 0.2 0.6 0.5 0.4 0.6 0.3 0.9 0.4 0.4 0.4 0.4 0.3 0.4 0.4 0.4 0.4 0.4 0.5 0.4 0.3 0.5 0.4 0.5 0.5 0.5 0.5 0.4 0.4 0.5 0.5 0.5 0.5 0.5 0.7 0.5 0.5 0.5 0.4 0.4 0.5 0.4 0.4 0.3 0.4 0.5 0.4 0.3 0.4 0.3 0.4 0.5
[1] 1drf.a 0.3 0.4 0.4
0
0.3 0.4 0.4 0.6 0.7 0.6 0.7 0.4 0.6 0.6 0.4 0.4 0.4 0.6 0.5 0.4 0.5 0.4 1.1 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.5 0.3 0.4 0.5 0.4 0.4 0.5 0.4 0.4 0.5 0.5 0.4 0.5 0.7 0.5 0.5 0.5 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.5 0.5 0.4 0.4 0.4 0.5 0.5
[1] 1hfp.a 0.2 0.3 0.3 0.3
0
0.2 0.2 0.6 0.6 0.6 0.6 0.4 0.5 0.6 0.2 0.5 0.2 0.6 0.5 0.4 0.5 0.3 0.9 0.4 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.4 0.3 0.5 0.3 0.3 0.5 0.3 0.4 0.5 0.4 0.4 0.4 0.4 0.5 0.5 0.4 0.4 0.5 0.7 0.5 0.5 0.5 0.4 0.3 0.4 0.4 0.4 0.3 0.3 0.4 0.3 0.3 0.3 0.3 0.3 0.4
[1] 1hfq.a 0.3 0.3 0.3 0.4 0.2
0
0.2 0.6 0.6 0.6 0.6 0.4 0.6 0.6 0.3 0.5 0.3 0.6 0.6 0.5 0.6 0.3 0.9 0.4 0.4 0.3 0.4 0.3 0.3 0.3 0.3 0.4 0.4 0.5 0.3 0.3 0.5 0.4 0.5 0.5 0.5 0.5 0.4 0.4 0.5 0.5 0.4 0.5 0.5 0.7 0.5 0.5 0.6 0.5 0.3 0.5 0.4 0.4 0.3 0.3 0.4 0.3 0.3 0.3 0.3 0.3 0.4
[1] 1hfr.a 0.2 0.3 0.2 0.4 0.2 0.2
0
0.6 0.6 0.6 0.6 0.4 0.5 0.6 0.3 0.5 0.2 0.6 0.5 0.4 0.5 0.3 0.9 0.4 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.4 0.3 0.5 0.3 0.3 0.5 0.3 0.4 0.5 0.4 0.5 0.4 0.4 0.5 0.5 0.4 0.5 0.5 0.7 0.5 0.5 0.5 0.4 0.3 0.4 0.3 0.4 0.3 0.3 0.4 0.3 0.3 0.3 0.3 0.3 0.5
[1] 1kms.a 0.5 0.5 0.6 0.6 0.6 0.6 0.6
0
0.3 0.8 0.8 0.6 0.7 0.8 0.6 0.6 0.6 0.7 0.6 0.6 0.7 0.6 1.0 0.7 0.7 0.7 0.7 0.6 0.7 0.6 0.6 0.5 0.6 0.7 0.7 0.6 0.7 0.6 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.6 0.7 0.6 0.8 0.6 0.7 0.7 0.6 0.7 0.6 0.6 0.6 0.6 0.6 0.7 0.6 0.7 0.6 0.6 0.6 0.7
[1] 1kmv.a 0.6 0.5 0.5 0.7 0.6 0.6 0.6 0.3
0
0.7 0.7 0.5 0.7 0.7 0.6 0.6 0.6 0.8 0.8 0.6 0.8 0.6 0.7 0.7 0.7 0.7 0.7 0.6 0.6 0.6 0.6 0.6 0.7 0.8 0.7 0.6 0.8 0.7 0.8 0.8 0.7 0.7 0.6 0.7 0.8 0.7 0.6 0.7 0.7 0.9 0.8 0.8 0.8 0.7 0.7 0.7 0.6 0.6 0.6 0.6 0.6 0.6 0.7 0.6 0.6 0.6 0.6
[1] 1mvt.a 0.5 0.6 0.6 0.6 0.6 0.6 0.6 0.8 0.7
0
0.8 0.5 0.7 0.2 0.5 0.6 0.6 0.7 0.7 0.6 0.8 0.6 1.0 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.6 0.6 0.7 0.7 0.7 0.7 0.6 0.7 0.8 0.7 0.6 0.7 0.6 0.7 0.6 0.7 0.7 0.7 0.8 0.7 0.6 0.6 0.6 0.7 0.6 0.6 0.6 0.6 0.6 0.7 0.7 0.6 0.6 0.6 0.7 0.7
[1] 1ohk.a 0.7 0.7 0.6 0.7 0.6 0.6 0.6 0.8 0.7 0.8
0
0.7 0.8 0.8 0.6 0.8 0.6 0.9 0.8 0.8 0.9 0.6 0.8 0.8 0.7 0.7 0.8 0.7 0.7 0.7 0.7 0.7 0.7 0.8 0.7 0.7 0.8 0.7 0.8 0.8 0.8 0.8 0.7 0.8 0.8 0.8 0.7 0.8 0.8 0.9 0.7 0.8 0.8 0.7 0.7 0.8 0.7 0.7 0.6 0.7 0.7 0.7 0.7 0.6 0.6 0.7 0.8
[1] 1pd9.a 0.3 0.3 0.4 0.4 0.4 0.4 0.4 0.6 0.5 0.5 0.7
0
0.5 0.5 0.4 0.3 0.4 0.6 0.6 0.4 0.6 0.5 0.9 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.6 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.7 0.6 0.5 0.5 0.5 0.5 0.4 0.4 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.6
[1] 1pdb.a 0.5 0.5 0.6 0.6 0.5 0.6 0.5 0.7 0.7 0.7 0.8 0.5
0
0.7 0.5 0.5 0.6 0.6 0.6 0.5 0.6 0.5 1.0 0.7 0.6 0.7 0.7 0.6 0.7 0.6 0.6 0.6 0.6 0.7 0.6 0.6 0.7 0.7 0.7 0.7 0.7 0.7 0.6 0.7 0.7 0.7 0.7 0.7 0.6 0.7 0.6 0.7 0.6 0.6 0.6 0.6 0.6 0.7 0.6 0.6 0.7 0.6 0.6 0.6 0.6 0.6 0.7
[1] 1s3v.a 0.5 0.6 0.6 0.6 0.6 0.6 0.6 0.8 0.7 0.2 0.8 0.5 0.7
0
0.6 0.6 0.6 0.6 0.7 0.6 0.8 0.7 1.1 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.6 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.6 0.7 0.7 0.6 0.7 0.7 0.6 0.6 0.6 0.7 0.6 0.6 0.7 0.7 0.7 0.7 0.7 0.7 0.7 0.6 0.7 0.8
[1] 1s3w.a 0.2 0.2 0.3 0.4 0.2 0.3 0.3 0.6 0.6 0.5 0.6 0.4 0.5 0.6
0
0.5 0.3 0.6 0.5 0.4 0.5 0.3 1.0 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.4 0.3 0.3 0.4 0.3 0.4 0.5 0.4 0.4 0.3 0.3 0.4 0.4 0.4 0.4 0.5 0.7 0.5 0.5 0.5 0.4 0.4 0.4 0.4 0.4 0.3 0.3 0.4 0.3 0.3 0.3 0.3 0.3 0.4
[1] 1u71.a 0.4 0.4 0.5 0.4 0.5 0.5 0.5 0.6 0.6 0.6 0.8 0.3 0.5 0.6 0.5
0
0.5 0.5 0.5 0.4 0.6 0.5 0.9 0.5 0.5 0.6 0.5 0.6 0.6 0.6 0.6 0.5 0.5 0.5 0.6 0.6 0.6 0.5 0.5 0.6 0.6 0.5 0.6 0.5 0.5 0.5 0.6 0.6 0.5 0.6 0.5 0.5 0.5 0.5 0.6 0.5 0.5 0.5 0.6 0.6 0.6 0.6 0.6 0.5 0.5 0.6 0.7
[1] 1u72.a 0.3 0.3 0.2 0.4 0.2 0.3 0.2 0.6 0.6 0.6 0.6 0.4 0.6 0.6 0.3 0.5
0
0.6 0.5 0.4 0.5 0.3 1.0 0.4 0.3 0.3 0.4 0.3 0.3 0.3 0.3 0.4 0.4 0.5 0.3 0.3 0.5 0.4 0.4 0.5 0.4 0.5 0.4 0.4 0.5 0.5 0.4 0.5 0.5 0.6 0.5 0.5 0.5 0.4 0.3 0.4 0.4 0.4 0.3 0.3 0.5 0.4 0.3 0.3 0.3 0.3 0.5
[1] 2c2s.b 0.5 0.6 0.6 0.6 0.6 0.6 0.6 0.7 0.8 0.7 0.9 0.6 0.6 0.6 0.6 0.5 0.6
0
0.1 0.5 0.3 0.5 1.2 0.7 0.6 0.6 0.7 0.7 0.7 0.7 0.7 0.5 0.6 0.7 0.7 0.7 0.6 0.6 0.5 0.6 0.7 0.7 0.7 0.7 0.7 0.6 0.8 0.8 0.2 0.2 0.3 0.3 0.2 0.3 0.5 0.4 0.5 0.7 0.6 0.7 0.8 0.8 0.7 0.6 0.5 0.7 0.8
[1] 2c2t.b 0.4 0.5 0.5 0.5 0.5 0.6 0.5 0.6 0.8 0.7 0.8 0.6 0.6 0.7 0.5 0.5 0.5 0.1
0
0.5 0.3 0.5 1.1 0.7 0.6 0.6 0.6 0.6 0.7 0.6 0.6 0.5 0.5 0.6 0.6 0.6 0.5 0.5 0.4 0.5 0.6 0.7 0.7 0.6 0.6 0.6 0.8 0.7 0.2 0.2 0.2 0.3 0.2 0.3 0.5 0.4 0.5 0.6 0.6 0.6 0.8 0.7 0.6 0.6 0.5 0.7 0.8
[1] 2dhf.b 0.3 0.4 0.4 0.4 0.4 0.5 0.4 0.6 0.6 0.6 0.8 0.4 0.5 0.6 0.4 0.4 0.4 0.5 0.5
0
0.5 0.4 1.0 0.5 0.4 0.5 0.5 0.5 0.5 0.5 0.5 0.4 0.5 0.5 0.5 0.5 0.5 0.4 0.5 0.6 0.5 0.5 0.5 0.5 0.5 0.5 0.6 0.5 0.5 0.6 0.5 0.5 0.5 0.4 0.5 0.3 0.5 0.5 0.5 0.5 0.6 0.6 0.5 0.5 0.5 0.5 0.6
[1] 2w3a.a 0.5 0.5 0.6 0.5 0.5 0.6 0.5 0.7 0.8 0.8 0.9 0.6 0.6 0.8 0.5 0.6 0.5 0.3 0.3 0.5
0
0.5 1.3 0.6 0.5 0.5 0.5 0.6 0.6 0.5 0.6 0.5 0.5 0.6 0.6 0.6 0.5 0.5 0.4 0.5 0.6 0.6 0.7 0.6 0.5 0.7 0.7 0.7 0.3 0.4 0.3 0.5 0.3 0.4 0.4 0.3 0.5 0.6 0.6 0.6 0.8 0.7 0.6 0.6 0.5 0.7 0.8
[1] 2w3b.a 0.3 0.4 0.3 0.4 0.3 0.3 0.3 0.6 0.6 0.6 0.6 0.5 0.5 0.7 0.3 0.5 0.3 0.5 0.5 0.4 0.5
0
1.0 0.4 0.3 0.3 0.4 0.3 0.3 0.3 0.3 0.3 0.4 0.5 0.3 0.3 0.5 0.4 0.5 0.5 0.5 0.5 0.4 0.4 0.5 0.5 0.4 0.5 0.4 0.6 0.4 0.5 0.5 0.3 0.2 0.4 0.4 0.4 0.3 0.3 0.5 0.4 0.4 0.3 0.3 0.3 0.5
[1] 3eig.a 1.0 1.0 0.9 1.1 0.9 0.9 0.9 1.0 0.7 1.0 0.8 0.9 1.0 1.1 1.0 0.9 1.0 1.2 1.1 1.0 1.3 1.0
0
1.1 1.1 1.1 1.1 1.1 1.0 1.1 1.0 1.1 1.1 1.2 1.0 1.1 1.1 1.1 1.1 1.2 1.1 1.1 1.1 1.1 1.2 1.1 1.1 1.1 1.1 1.2 1.1 1.1 1.1 1.1 1.1 1.2 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0
[1] 3f8y.a 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.7 0.7 0.7 0.8 0.5 0.7 0.7 0.3 0.5 0.4 0.7 0.7 0.5 0.6 0.4 1.1
0
0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.4 0.2 0.3 0.2 0.3 0.4 0.2 0.5 0.5 0.3 0.3 0.2 0.2 0.3 0.5 0.3 0.2 0.6 0.8 0.6 0.6 0.7 0.6 0.4 0.5 0.4 0.3 0.3 0.2 0.3 0.3 0.2 0.3 0.4 0.3 0.3
[1] 3f8z.a 0.3 0.4 0.4 0.4 0.3 0.4 0.3 0.7 0.7 0.7 0.7 0.5 0.6 0.7 0.3 0.5 0.3 0.6 0.6 0.4 0.5 0.3 1.1 0.2
0
0.1 0.1 0.2 0.2 0.2 0.2 0.4 0.2 0.3 0.2 0.2 0.4 0.2 0.4 0.4 0.3 0.4 0.3 0.2 0.3 0.5 0.4 0.3 0.5 0.7 0.5 0.5 0.6 0.5 0.3 0.4 0.3 0.3 0.3 0.2 0.4 0.4 0.3 0.3 0.3 0.3 0.4
[1] 3f91.a 0.3 0.4 0.4 0.4 0.3 0.3 0.3 0.7 0.7 0.7 0.7 0.5 0.7 0.7 0.3 0.6 0.3 0.6 0.6 0.5 0.5 0.3 1.1 0.2 0.1
0
0.1 0.2 0.2 0.2 0.2 0.4 0.2 0.3 0.2 0.2 0.4 0.2 0.4 0.5 0.3 0.3 0.2 0.2 0.3 0.5 0.4 0.3 0.5 0.7 0.5 0.5 0.6 0.5 0.4 0.4 0.3 0.3 0.3 0.2 0.3 0.3 0.2 0.2 0.3 0.3 0.4
[1] 3fs6.a 0.3 0.4 0.4 0.4 0.3 0.4 0.3 0.7 0.7 0.7 0.8 0.5 0.7 0.7 0.3 0.5 0.4 0.7 0.6 0.5 0.5 0.4 1.1 0.2 0.1 0.1
0
0.2 0.2 0.2 0.2 0.4 0.2 0.3 0.2 0.2 0.4 0.2 0.4 0.5 0.3 0.3 0.3 0.2 0.3 0.4 0.4 0.2 0.6 0.7 0.6 0.6 0.6 0.5 0.4 0.4 0.4 0.3 0.3 0.2 0.3 0.4 0.3 0.3 0.3 0.3 0.4
[1] 3ghc.a 0.4 0.4 0.3 0.4 0.3 0.3 0.3 0.6 0.6 0.7 0.7 0.5 0.6 0.7 0.3 0.6 0.3 0.7 0.6 0.5 0.6 0.3 1.1 0.2 0.2 0.2 0.2
0
0.1 0.1 0.1 0.4 0.3 0.4 0.1 0.1 0.5 0.3 0.5 0.5 0.3 0.4 0.2 0.3 0.4 0.5 0.3 0.3 0.6 0.8 0.6 0.6 0.6 0.5 0.3 0.5 0.4 0.3 0.2 0.2 0.3 0.3 0.2 0.2 0.3 0.2 0.3
[1] 3ghv.a 0.4 0.4 0.4 0.4 0.3 0.3 0.3 0.7 0.6 0.7 0.7 0.5 0.7 0.7 0.3 0.6 0.3 0.7 0.7 0.5 0.6 0.3 1.0 0.2 0.2 0.2 0.2 0.1
0
0.1 0.1 0.4 0.3 0.4 0.1 0.2 0.5 0.3 0.5 0.6 0.3 0.4 0.2 0.3 0.4 0.5 0.3 0.3 0.6 0.8 0.6 0.6 0.6 0.5 0.4 0.5 0.4 0.3 0.2 0.2 0.3 0.3 0.2 0.2 0.3 0.2 0.3
[1] 3ghw.a 0.3 0.4 0.4 0.4 0.3 0.3 0.3 0.6 0.6 0.7 0.7 0.5 0.6 0.7 0.3 0.6 0.3 0.7 0.6 0.5 0.5 0.3 1.1 0.2 0.2 0.2 0.2 0.1 0.1
0
0.1 0.4 0.3 0.4 0.1 0.1 0.5 0.3 0.4 0.5 0.3 0.4 0.3 0.3 0.4 0.5 0.3 0.3 0.6 0.8 0.5 0.6 0.6 0.5 0.3 0.5 0.4 0.3 0.2 0.2 0.3 0.3 0.3 0.2 0.3 0.2 0.3
[1] 3gi2.a 0.4 0.4 0.4 0.4 0.3 0.3 0.3 0.6 0.6 0.7 0.7 0.5 0.6 0.7 0.3 0.6 0.3 0.7 0.6 0.5 0.6 0.3 1.0 0.2 0.2 0.2 0.2 0.1 0.1 0.1
0
0.4 0.3 0.4 0.1 0.1 0.5 0.3 0.5 0.5 0.3 0.4 0.3 0.3 0.4 0.5 0.3 0.3 0.6 0.8 0.6 0.6 0.6 0.5 0.3 0.5 0.4 0.3 0.2 0.2 0.3 0.2 0.2 0.2 0.3 0.2 0.3
[1] 3gyf.a 0.3 0.3 0.4 0.4 0.4 0.4 0.4 0.5 0.6 0.6 0.7 0.5 0.6 0.6 0.3 0.5 0.4 0.5 0.5 0.4 0.5 0.3 1.1 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.4
0
0.4 0.5 0.4 0.4 0.5 0.4 0.5 0.6 0.4 0.4 0.5 0.4 0.5 0.5 0.5 0.5 0.4 0.6 0.4 0.5 0.4 0.3 0.4 0.3 0.4 0.4 0.4 0.4 0.5 0.5 0.5 0.4 0.3 0.4 0.5
[1] 3l3r.a 0.3 0.4 0.4 0.4 0.3 0.4 0.3 0.6 0.7 0.6 0.7 0.5 0.6 0.7 0.3 0.5 0.4 0.6 0.5 0.5 0.5 0.4 1.1 0.2 0.2 0.2 0.2 0.3 0.3 0.3 0.3 0.4
0
0.3 0.3 0.3 0.3 0.2