DYR_CHICK_1_189

Dihydrofolate reductase [Dihydrofolate reductase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (DYR_CHICK):D: DHFR (7:9,22,30,31,34,56,115)
R: Substrate binding (30,31,34)
7:9,22,30,31,34,56,115
Cofactors (cF):nap/tap
Metals (Me):Ca

Full PDB list

1dr1,1dr2,1dr3,1dr4,1dr5,1dr6,1dr7,8dfr (redundant pocketome entry)

Contact map

[download in TSV format]
   
PDB.ch
   
ligand
A1 cF Me
I
7
V
8
A
9
L
2
2
E
3
0
Y
3
1
F
3
4
T
5
6
V
1
1
5
[1]1dr2.a none . . . . . . . . . tap Ca
[1]1dr6.a hbi 17 . . . . . . . . . nap Ca

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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