DYRA_STAAU_1_161

Dihydrofolate reductase type 1 from Tn4003 [Dihydrofolate reductase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (DYRA_STAAU):D: DHFR (6:8,21,28,29,32,50,51,93,99)
R: Substrate binding (6:8)
6:8,21,28,29,32,50,51,93,99
Cofactors (cF):ndp

Full PDB list

2w9s,2w9t

Contact map

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ligand
A1 cF
I
6
V
7
A
8
L
2
1
D
2
8
L
2
9
I
3
2
S
5
0
I
5
1
F
9
3
Y
9
9
[1]2w9s.a top 21 . . . . . . . . . . . ndp
[2]2w9t.a none . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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