DYR21_ECOLX_17_78

Dihydrofolate reductase type 2

ActiveICM:

L C E

Composition of the binding pockets

Protein chains homotetramer
 • A1 (DYR21_ECOLX):32,36,66:6932,36,66:69
 • A2 (DYR21_ECOLX):32,35,36,50,70,72,7332,35,36,50,70,72,73
 • A3 (DYR21_ECOLX):6868
 • A4 (DYR21_ECOLX):64:6764:67

Full PDB list

1vie,1vif,2gqv,2p4t,2rh2,2rk1,2rk2,3sfm (redundant pocketome entry)

Contact map

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ligand
A1 A2 A3 A4
K
3
2
A
3
6
V
6
6
Q
6
7
I
6
8
Y
6
9
K
3
2
G
3
5
A
3
6
L
5
0
P
7
0
A
7
2
A
7
3
I
6
8
G
6
4
S
6
5
V
6
6
Q
6
7
[1]2rk1.a nap 48 . . . . . . . . . . . . . . . . . .
[1]1vif.a fol 13 . . . . . . . . . . . . . . . . . .
[1]2p4t.a nap 26 . . . H . . . . . . . . . . . . . H
[1]3sfm.a none . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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