DXR_PLAF7_75_488

1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic [DXR family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (DXR_PLAF7):R: Binding to substrate phosphate group (269,270)
R: Substrate binding (311,312,315)
205,231:233,293:296,298,302,303,306,338,341,358:360,363
205,231:233,269,270,293:296,298,302,303,306,311,312,315,338,341,358:360,363
Metals (Me):Mg/Mn

Full PDB list

3au8,3au9,3aua,3wqq,3wqr,3wqs,4gae,4kp7,4y67,4y6p,4y6r,4y6s,5jaz,5jbi,5jc1,5jmp,5jmw,5jnl,5jo0

Contact map

[download in TSV format]
   
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ligand
A1 Me
K
2
0
5
D
2
3
1
S
2
3
2
E
2
3
3
S
2
6
9
S
2
7
0
H
2
9
3
P
2
9
4
K
2
9
5
W
2
9
6
M
2
9
8
I
3
0
2
T
3
0
3
S
3
0
6
N
3
1
1
K
3
1
2
E
3
1
5
C
3
3
8
H
3
4
1
P
3
5
8
D
3
5
9
M
3
6
0
P
3
6
3
[1]5jnl.a l54 25 . . . . . . . . . . . . . . . . . . . . . . . Mn
[1]5jaz.a lc5 25 . . . . . . . . . . . . . . . . . . . . . . . Mn
[1]5jbi.a 6j8 23 . . . . . . . . . . . . . . . . . . . . . . . Mn
[1]5jc1.a 6jb 23 . . . . . . . . . . . . . . . . . . . . . . . Mn
[1]5jmw.a l50 22 . . . . . . . . . . . . . . . . . . . . . . . Mn
[1]5jo0.a l56 22 . . . . . . . . . . . . . . . . . . . . . . . Mn
[1]5jmp.a lc7 22 . . . . . . . . . . . . . . . . . . . . . . . Mn
[1]4y6p.a r77 22 . . . . . . . . . . . . . . . . . . . . . . . Mn
[1]4y67.a rc5 21 . . . . . . . . . . . . . . . . . . . . . . . Mn
[1]3wqs.b kbk 20 . . . . . . . . . . . . . . . . . . . . . . . Mg
[1]3wqr.a lsx 20 . . . . . . . . . . . . . . . . . . . . . . . Mg
[2]4y6s.a 48s 19 . . . . . . . . . . . . . . . . . . . . . . . Mn
[1]3wqq.a ib3 19 . . . . . . . . . . . . . . . . . . . . . . . Mg
[1]4kp7.a 1uq 18 . . . . . . . . . . . . . . . . . . . . . . . Mn
[2]4y6r.a rf7 18 . . . . . . . . . . . . . . . . . . . . . . . Mn
[1]4gae.b fob,foq 36 . . . . . . . . . . . . . . . . . . . . . . . Mn
[2]3aua.b f98 12 . . . . . . . . . . . . . . . . . . . . . . . Mg
[2]3au9.a fom 11 . . . . . . . . . . . . . . . . . . . . . . . Mg
[1]3au8.a none . . . . . . - - - - - . . . . . . . . . . . . Mn

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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