DXR_MYCTU_1_390

1-deoxy-D-xylulose 5-phosphate reductoisomerase [DXR family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (DXR_MYCTU):19,21:24,46:50,69,103:105,108,126:129,151:153,176,177,200,203,205:207,209,210,213,218,219,222,245,248,265,26719,21:24,46:50,69,103:105,108,126:129,151:153,176,177,200,203,205:207,209,210,213,218,219,222,245,248,265,267
Metals (Me):Mn

Full PDB list

2c82,2jcv,2jcx,2jcy,2jd0,2jd1,2jd2,2y1c,2y1d,2y1e,2y1f,2y1g,3ras,3zhx,3zhy,3zhz,3zi0,4a03,4aic,4ooe,4oof,4rcv (redundant pocketome entry)

Contact map

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ligand
A1 Me
G
1
9
T
2
1
G
2
2
S
2
3
I
2
4
A
4
6
G
4
7
G
4
8
A
4
9
H
5
0
A
6
9
A
1
0
3
L
1
0
4
V
1
0
5
L
1
0
8
A
1
2
6
N
1
2
7
K
1
2
8
E
1
2
9
D
1
5
1
S
1
5
2
E
1
5
3
A
1
7
6
S
1
7
7
H
2
0
0
W
2
0
3
M
2
0
5
G
2
0
6
P
2
0
7
N
2
0
9
T
2
1
0
S
2
1
3
N
2
1
8
K
2
1
9
E
2
2
2
S
2
4
5
H
2
4
8
P
2
6
5
M
2
6
7
[1]3zi0.a fm8 31 . . . . . . . . . . - . . . . . . . . . . . . . - - - - . . . . . . . . . . .
[1]3zhz.a fm7 36 . . . . . . . . . . . . . . . . . . . . . . . . . - - - - . . . . . . . . . .
[1]3zhx.a fm6 25 . . . . . . . . . . . . . . . . . . . . . . . . - - - - . . . . . . . . . . . Mn
[1]2y1d.a 34f 19 . . . . . . . . . . - . . . . . . . . . . . . . - - - - - . . . . . . . . . . Mn
[1]2y1g.a fm5 20 . . . . . . . . . . . . . . . . . . . . . . . . - - . . . . . . . . . . . . . Mn
[2]4a03.a f98,ndp 60 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Mn
[2]2jcv.a fom,ndp 59 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3zhy.a fm6,ndp 73 . . . . . . . . . . . . . . . . . . . . . . . . - - . . . . . . . . . . . . . Mn
[1]2y1f.a 34f,ndp 67 . . . . . . . . . . . . . . . . . . . . . . . . - - . . . . . . . . . . . . . Mn
[1]3ras.a dcv,fm5,ndp 88 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Mn
[2]2jcx.a fom,ndp 50 . . . . . . . . . . . . . . . . . . . N . . . . . . . . . . . . . . Q . . . .
[2]2jcy.a none . . . . . . . . . . . . . . . . . . . N . . . . . . . . . . . . . . Q . . . .
[2]2jd0.a ndp 27 . . . . . . . . . . . . . . . . . . . N . . . . . . . . . . . . . . Q . . . .
[2]4ooe.c fom,ndp 59 . . . . . . . . . . . . . . . . . . . . . . . . . Y . . . . . . . . . . . . . Mn
[2]2jd1.a ndp 48 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Mn
[2]4oof.a fom,ndp 59 . . . . . . . . . . . . . . . . . . . . . . . . . F . . . . . . . . . . . . . Mn
[2]2jd2.a none . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Mn
[1]4rcv.a de2,ndp 55 . . . . . . . . . . . . . . . . . . . . . . . . - - - - . . . . . . . . . . . Mn

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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