DXR_ECOLI_1_398

1-deoxy-D-xylulose 5-phosphate reductoisomerase [DXR family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (DXR_ECOLI):R: Binding to substrate phosphate group (222,227,228)
125,150:152,185,186,209,211,212,214,218,231,254,257,274,276
125,150:152,185,186,209,211,212,214,218,222,227,228,231,254,257,274,276

Full PDB list

1jvs,1k5h,1onn,1ono,1onp,1q0h,1q0l,1q0q,1t1r,1t1s,2egh,3anl,3anm,3ann,3r0i (redundant pocketome entry)

Contact map

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ligand
A1
K
1
2
5
D
1
5
0
S
1
5
1
E
1
5
2
G
1
8
5
S
1
8
6
H
2
0
9
N
2
1
1
W
2
1
2
M
2
1
4
I
2
1
8
S
2
2
2
N
2
2
7
K
2
2
8
E
2
3
1
S
2
5
4
H
2
5
7
P
2
7
4
M
2
7
6
[2]3r0i.b c0k,mn 21 . . . . . . - - - . . . . . . . . . .
[1]1t1r.a imb 20 . . . . . . . . . . . . . . . . . . .
[1]1t1s.a cbq,mg 18 . . . . . . . . . . . . . . . . . . .
[1]1t1s.b cbq 17 . . . . . . . . . . . . . . . . . . .
[2]3anm.b syd 17 . . . . . . . . . . . . . . . . . . .
[2]3ann.a sye 15 . . . . . . . . . . . . . . . . . . .
[2]3anl.a syc 11 . . . . . . . . . . . . . . . . . . .
[1]1q0q.a dxp 13 . . . . . . . . . . . . . . . . . . .
[1]1onp.a fom,mn 12 . . . . . . . . . . . . . . . . . . .
[1]1jvs.b none . . . . . . . . . * . . . . . . . . *
[1]1q0h.a fom 11 . . . . . . . . . * . . . . . . . . *
[1]1q0l.a fom 11 . . . . . . . . . . . . . . . . . . .
[2]1onn.a none . . . . . . - - - - . . . . . . . . .
[1]2egh.b fom,mg 12 . . . . . . . . . . . . . . . . . . .
[2]1ono.a mn 1 . . . . . . - - - - . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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