DPYD_PIG_1_1025_NADPH

Dihydropyrimidine dehydrogenase [NADP(+)] [Dihydropyrimidine dehydrogenase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (DPYD_PIG):291,339:341,343,364,365,371,393,437,438,481,487291,339:341,343,364,365,371,393,437,438,481,487
Cofactors (cF):fad/sf4

Full PDB list

1gt8,1gte,1gth,1h7w,1h7x (redundant pocketome entry)

Contact map

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ligand
A1 cF
D
2
9
1
G
3
3
9
A
3
4
0
G
3
4
1
T
3
4
3
R
3
6
4
K
3
6
5
R
3
7
1
P
3
9
3
A
4
3
7
F
4
3
8
D
4
8
1
N
4
8
7
[1]1h7w.a none . . . . . . . . . . . . . fad,sf4
[1]1h7x.a ndp 39 . . . . . . . . . . . . . fad,sf4

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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