DNK_DROME_1_233

Deoxynucleoside kinase [DCK/DGK family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (DNK_DROME):29:34,52,54,57,66,69,70,80,81,84,88,104:106,109,110,114,118,167,169,17229:34,52,54,57,66,69,70,80,81,84,88,104:106,109,110,114,118,167,169,172

Full PDB list

1j90,1oe0,1ot3,1zm7,1zmx,2jcs,2jj8,2vp0,2vp2,2vp4,2vp5,2vp6,2vp9,2vpp,2vqs (redundant pocketome entry)

Contact map

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ligand
A1
I
2
9
G
3
0
S
3
1
G
3
2
K
3
3
T
3
4
E
5
2
V
5
4
W
5
7
L
6
6
M
6
9
Y
7
0
F
8
0
Q
8
1
V
8
4
M
8
8
E
1
0
4
R
1
0
5
S
1
0
6
S
1
0
9
A
1
1
0
F
1
1
4
M
1
1
8
R
1
6
7
R
1
6
9
E
1
7
2
[1]2vpp.b geo 18 . . . . . . . . . . . . . . . . . . . . . . . . - .
[1]2vp4.a dcp 28 . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2jj8.d azz 19 . . . . . . . . . . . . . . . . . . . . . . . . - -
[1]2vqs.b bvd 19 . . . . . . . . . . . . . . . . . . . . . . . . - -
[1]2vp6.b 5fu 17 . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2vp2.a dgt 31 . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2vp9.d doc 15 . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1ot3.a thm 17 . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1zm7.a ttp 29 . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1zm7.d mg,ttp 30 . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2vp5.b dcz 16 . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2jcs.a mg,ttp 30 . . . . . . D . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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