DHYS_HUMAN_2_369

Deoxyhypusine synthase [Deoxyhypusine synthase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains homodimer[show domain annotation]
 • A1 (DHYS_HUMAN):R: Spermidine binding (314:316)
R: Spermidine binding (323,327,329)
288,292,295,319
288,292,295,314:316,319,323,327,329
 • A2 (DHYS_HUMAN):106,166,243106,166,243

Full PDB list

1dhs,1rlz,1roz,1rqd (redundant pocketome entry)

Contact map

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ligand
A1 A2
H
2
8
8
N
2
9
2
L
2
9
5
G
3
1
4
S
3
1
5
D
3
1
6
A
3
1
9
E
3
2
3
W
3
2
7
K
3
2
9
N
1
0
6
I
1
6
6
D
2
4
3
[1]1rqd.a gc7 12 . . . . . . . . . . . . .
[1]1dhs.a none . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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