DHI1_CAVPO_25_296

Corticosteroid 11-beta-dehydrogenase isozyme 1 [Short-chain dehydrogenases/reductases (SDR) family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (DHI1_CAVPO):123,124,126,170:172,177,180,183,215:217,223,226,227,231123,124,126,170:172,177,180,183,215:217,223,226,227,231
Cofactors (cF):nap

Full PDB list

1xse,3dwf,3g49,3lz6 (redundant pocketome entry)

Contact map

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ligand
A1 cF
Y
1
2
3
N
1
2
4
L
1
2
6
S
1
7
0
V
1
7
1
A
1
7
2
Y
1
7
7
I
1
8
0
Y
1
8
3
L
2
1
5
G
2
1
6
L
2
1
7
A
2
2
3
A
2
2
6
T
2
2
7
Y
2
3
1
[1]3g49.a 3g4 26 . . . . . . . . . . . . . . . . nap
[1]3lz6.a a0d 20 . . . . . . . . . . . . . . . . nap
[2]3dwf.a none . . . . . . . . . . . . . . . . nap

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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