DDAH1_HUMAN_2_285

N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 [DDAH family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (DDAH1_HUMAN):R: Substrate binding (78,79)
30,73,76,98,129,145,172,173,175,176,221,268:271,273,274
30,73,76,78,79,98,129,145,172,173,175,176,221,268:271,273,274

Full PDB list

2c6z,2ci1,2ci3,2ci4,2ci5,2ci6,2ci7,2jai,2jaj,3i2e,3i4a,3p8e,3p8p (redundant pocketome entry)

Contact map

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ligand
A1
L
3
0
D
7
3
F
7
6
E
7
8
D
7
9
R
9
8
G
1
2
9
R
1
4
5
L
1
7
2
H
1
7
3
K
1
7
5
S
1
7
6
N
2
2
1
V
2
6
8
D
2
6
9
G
2
7
0
L
2
7
1
T
2
7
3
C
2
7
4
[1]2jaj.a d20 16 . . . . . . . . . . . . . . . . . . .
[1]3p8p.a ln6 15 . . . . . . . . . . . . . . . . . . S
[1]3p8e.a ln7 15 . . . . . . . . . . . . . . . . . . *
[1]3i4a.a ln5 13 . . . . . . . . . . . . . . . . . . *
[1]2c6z.a cir 12 . . . . . . . . . . . . . . . . . . .
[2]2ci1.a none . . . . . . . . . . . . . . . . . . *
[1]2ci3.a none . . . . . . . . . . . . . . . . . . .
[1]2ci5.a hcs 8 . . . . . . . . . . . . . . . . . . .
[1]2ci6.a zn 1 . . . . . . . . . . . . . . . . . . .
[1]2ci7.a G,zn 6 . . . . . . . . . . . . . . . . . . .
[1]2jai.a cir 12 . . . . . . . . . . . . . . . . . . .
[1]3i2e.a none . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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