DCUP_HUMAN_2_367

Uroporphyrinogen decarboxylase [Uroporphyrinogen decarboxylase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (DCUP_HUMAN):R: Substrate binding (37:41)
36,46,50,55,82:88,100,106,154,164,170,217,219,261,339
36:41,46,50,55,82:88,100,106,154,164,170,217,219,261,339

Full PDB list

1jph,1jpi,1jpk,1r3q,1r3r,1r3s,1r3t,1r3v,1r3w,1r3y,1uro,2q6z,2q71,3gvq,3gvr,3gvv,3gvw,3gw0,3gw3 (redundant pocketome entry)

Contact map

[download in TSV format]
   
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ligand
A1
M
3
6
R
3
7
Q
3
8
A
3
9
G
4
0
R
4
1
F
4
6
R
5
0
F
5
5
I
8
2
I
8
3
F
8
4
S
8
5
D
8
6
I
8
7
L
8
8
M
1
0
0
P
1
0
6
F
1
5
4
Y
1
6
4
G
1
7
0
F
2
1
7
S
2
1
9
F
2
6
1
H
3
3
9
[1]1r3q.a 1cp 48 . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1r3t.a cp3 48 . . . . . . . . . . . . . G . . . . . . . . . . .
[1]1r3s.a 1cp 48 . . . . . . . . . . . . . G . . . . . . . . . . .
[1]1r3w.a cp3 48 . . . . . . . . . . . . . . . . . . . F . . . . .
[1]1r3v.a 1cp 48 . . . . . . . . . . . . . E . . . . . . . . . . .
[1]1r3y.a cp3 48 . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1jpk.a none . . . . . . . . - . . . . . . . - . . . . . . . .
[1]1r3r.a none . . . . . . . . . . . . . N . . . . . . . . . . .
[1]3gvr.a none . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3gvw.a none . . . . . . . . . . . . . . . . . . . . . Y . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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