DCIP_AZOBR_2_545_allosteric

Indole-3-pyruvate decarboxylase [TPP enzyme family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (DCIP_AZOBR):R: Thiamine pyrophosphate binding (394:397)
60,61,214,215,238,240:242,375
60,61,214,215,238,240:242,375,394:397

Full PDB list

2nxw,2q5j,2q5l,2q5o,2q5q (redundant pocketome entry)

Contact map

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ligand
A1
R
6
0
Y
6
1
R
2
1
4
R
2
1
5
M
2
3
8
R
2
4
0
G
2
4
1
L
2
4
2
L
3
7
5
G
3
9
4
L
3
9
5
M
3
9
6
A
3
9
7
[1]2q5q.a kpv 14 . . . . . . . . . . . . .
[1]2nxw.a none . . . . . . . . . . . . .
[1]2q5o.a ppy 12 . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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