DCE1_HUMAN_92_594

Glutamate decarboxylase 1 [Group II decarboxylase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains homodimer[show domain annotation]
 • A1 (DCE1_HUMAN):R: Substrate binding (190:192)
189,251:253,291,344,346,348,373,375,376,402,404,405,567
189:192,251:253,291,344,346,348,373,375,376,402,404,405,567
 • A2 (DCE1_HUMAN):214,434,435,455,456214,434,435,455,456

Full PDB list

2okj,3vp6

Contact map

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ligand
A1 A2
N
1
8
9
Q
1
9
0
L
1
9
1
S
1
9
2
G
2
5
1
G
2
5
2
A
2
5
3
H
2
9
1
T
3
4
4
G
3
4
6
T
3
4
8
D
3
7
3
A
3
7
5
W
3
7
6
N
4
0
2
H
4
0
4
K
4
0
5
R
5
6
7
F
2
1
4
Y
4
3
4
L
4
3
5
C
4
5
5
G
4
5
6
[1]2okj.a abu,plp 22 . . . . . . . . . . . . . . . . * . . . . . .
[1]2okj.b abu,plp,plz 44 . . . . . . . . . . . . . . . . * . . . . . .
[1]3vp6.b hld,plp 28 . . . . . . . . . . . . . . . . * . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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