If you see this message after the page is completely loaded, then JavaScript is not supported or disabled in your browser. Please consider enabling JavaScript for this site.

CUSC_ECOLI_18_457

Cation efflux system protein CusC [Outer membrane factor (OMF) (TC 1.B.17) family]

Composition of the binding site

Protein chains homotrimer
A1 (CUSC_ECOLI):18, 136, 137, 30818, 136, 137, 308
A2 (CUSC_ECOLI):308, 336, 338308, 336, 338
A3 (CUSC_ECOLI):107, 108107, 108

Full PDB list

3pik, 4k7r (Pocketome entry); 4k34, 4k7k (unprocessed)

Pocket contact map

[download in TSV format]
   
PDB.ch
   
ligand
A1 A2 A3
C
1
8
F
1
3
6
F
1
3
7
I
3
0
8
I
3
0
8
P
3
3
6
I
3
3
8
S
1
0
7
[1]3pik.a unl18 * . . . . . . .
[1]4k7r.a 3pk18 . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)

Site contact map

[download in TSV format]
   
PDB.ch
A1 A2 A3
C
1
8
F
1
3
6
F
1
3
7
I
3
0
8
I
3
0
8
P
3
3
6
I
3
3
8
S
1
0
7
G
1
0
8
[1]3pik.a * . . . . . . . .
[1]4k7r.a * . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)

Pocket-ligand steric compatibility

Ligands (x) vs pockets (y) colored by number of steric clashes

zoom: [−] [+]; [view as image]; [download as text]

pocketligand
≥10
9
8
7
6
5
4
3
2
1
0
3pik.a:unl
4k7r.a:3pk
[1] 3pik.a
1.0
0.6
[1] 4k7r.a 1.0
0
[Pocket-ligand steric clashes matrix]

Pocket clash dissimilarity (1 cluster)

Pockets (x) vs pockets (y) colored by ligand clash profile difference

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥1.
.9
.8
.7
.6
.5
.4
.3
.2
.1
.0
3pik.a
4k7r.a
[1] 3pik.a
0
.09
[1] 4k7r.a .09
0
[Pocket clash dissimilarity matrix]

Site backbone RMSD (median 0.4 Å)

Pockets (x) vs pockets (y) colored by RMSD of site residue backbone atoms

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥10 Å
9 Å
8 Å
7 Å
6 Å
5 Å
4 Å
3 Å
2 Å
1 Å
0 Å
3pik.a
4k7r.a
[1] 3pik.a
0
0.4
[1] 4k7r.a 0.4
0
[Binding site backbone RMSD matrix]

Site full-atom RMSD (median 0.2 Å)

Pockets (x) vs pockets (y) colored by RMSD of all site residue atoms

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥10 Å
9 Å
8 Å
7 Å
6 Å
5 Å
4 Å
3 Å
2 Å
1 Å
0 Å
3pik.a
4k7r.a
[1] 3pik.a
0
0.8
[1] 4k7r.a 0.8
0
[Binding site full-atom RMSD matrix]







[show 3D visualization]

[ENTRY 2D visualization]

L C X E | Background Color: | Anaglyph Stereo:

loading...