CTDS1_HUMAN_76_258

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (CTDS1_HUMAN):D: FCP1 homology (96:98,104:107,118,120,121,125,152:155,157,158,178,187,188,190,208)96:98,104:107,118,120,121,125,152:155,157,158,178,187,188,190,208
Metals (Me):Mg

Full PDB list

1t9z,1ta0,2ghq,2ght,3l0b,3l0c,3l0y,3pgl,4ygy,4yh1 (redundant pocketome entry)

Contact map

[download in TSV format]
   
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ligand
A1 Me
D
9
6
L
9
7
D
9
8
S
1
0
4
S
1
0
5
F
1
0
6
K
1
0
7
V
1
1
8
I
1
2
0
D
1
2
1
H
1
2
5
T
1
5
2
A
1
5
3
S
1
5
4
L
1
5
5
K
1
5
7
Y
1
5
8
R
1
7
8
N
1
8
7
Y
1
8
8
K
1
9
0
S
2
0
8
[1]3pgl.a rzx 25 . . . . . . . . . . . . . . . . . . . . . . Mg
[1]3l0b.a 1pg 17 * . . . . . . . . . . . . . . . . . . . . . Mg
[1]3l0b.b none * . . . . . . . . . . . . . . . . . . . . .
[1]1ta0.a none * . . . . . . . . . . . . . . . . . . . . . Mg
[1]2ghq.a sepPTsepP 41 N . . . . . . . . . . . . . . . . . . . . . Mg
[1]2ghq.b PSYsepPTsepPS 73 N . . . . . . . . . . . . . . . . . . . . . Mg
[1]2ght.a SPTsepP 37 N . . . . . . . . . . . . . . . . . . . . . Mg
[1]2ght.b SYSPTsepPS 62 N . . . . . . . . . . . . . . . . . . . . . Mg
[1]3l0c.b none . . . . . . . . . . . . . . . . . . . . . . Mg
[1]3l0y.b none . . A . . . . . . . . . . . . . . . . . . . Mg
[1]4yh1.a SPT4cg 36 N . . . . . . . . . . . . . . . . . . . . . Mg

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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