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CRTM_STAAU_1_287

4,4'-diapophytoene synthase [Phytoene/squalene synthase family. CrtM subfamily]

Composition of the binding site

Protein chains monomer [domain annotation]
A1 (CRTM_STAAU):R: Farnesyl diphosphate 1 binding (18:21)
15, 17, 22, 25, 26, 29, 37, 40, 41, 44, 45, 48, 49, 52, 107, 111, 114, 117, 129, 133, 134, 137, 138, 141, 145, 157, 160, 161, 164, 165, 167:169, 171, 172, 176, 181, 183, 233, 240, 241, 243:245, 247:249, 251, 265:267
15, 17:22, 25, 26, 29, 37, 40, 41, 44, 45, 48, 49, 52, 107, 111, 114, 117, 129, 133, 134, 137, 138, 141, 145, 157, 160, 161, 164, 165, 167:169, 171, 172, 176, 181, 183, 233, 240, 241, 243:245, 247:249, 251, 265:267
Metals (Me):Mg

Full PDB list

2zco, 2zcq, 2zcr, 2zcs, 2zy1, 3acw, 3acx, 3acy, 3adz, 3ae0, 3lgz, 3npr, 3nri, 3tfn, 3tfp, 3tfv, 3vjd, 3vje, 3w7f, 4e9u, 4e9z, 4ea0, 4ea1, 4ea2, 4f6v, 4f6x (redundant Pocketome entry)

Pocket contact map

[download in TSV format]
   
PDB.ch
   
ligand
A1 Me
M
1
5
H
1
8
S
1
9
K
2
0
S
2
1
F
2
2
A
2
5
F
2
6
V
3
7
I
4
0
Y
4
1
C
4
4
R
4
5
D
4
8
D
5
2
L
1
0
7
V
1
1
1
D
1
1
4
Y
1
2
9
V
1
3
3
A
1
3
4
V
1
3
7
G
1
3
8
L
1
4
1
L
1
4
5
A
1
5
7
L
1
6
0
G
1
6
1
L
1
6
4
Q
1
6
5
I
1
6
7
N
1
6
8
R
1
7
1
D
1
7
2
D
1
7
6
F
2
3
3
I
2
4
1
A
2
4
4
I
2
4
7
Y
2
4
8
I
2
5
1
R
2
6
5
V
2
6
6
F
2
6
7
[1]2zco.a none . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2zcq.a b65,mg26 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Mg
[1]2zcr.a b6928 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Mg
[1]2zcs.a b7024 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2zy1.a 83024 . . . . . . . . . . . . . . - . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3acw.a 65121 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3acx.a 67323 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3acy.a 70232 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Mg
[1]3adz.a mg,ps740 . . . . . . . . . . . . . . . . . . A . . . . . . . . . . . . . . . . . . . . . . . . . Mg
[1]3npr.a mg,ps740 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Mg
[1]3nri.a dh730 . . . . . . . . . . . . . . - . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3tfn.a 2cj,mg32 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3tfp.a 03l,mg30 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Mg
[1]3tfv.a 2cn27 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Mg
[1]4e9u.a rwy19 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4ea0.a 651,mg,mg23 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Mg
[1]4ea1.a 3rx24 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4ea2.a mg,rwz,srt35 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4f6v.a fjp,mg,srt,zym56 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Mg
[1]4f6x.a mg,mg,tar,zyl35 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Mg
[2]3ae0.b ggs,ggs,mg,mg60 . . . . . . . A . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Mg
[2]3vje.b zga49 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . A . . . .
[2]3w7f.b fps,fps,mg,mg50 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Mg
[3]3vjd.a none . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . A . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)

Site contact map

[download in TSV format]
   
PDB.ch
A1 Me
M
1
5
K
1
7
H
1
8
S
1
9
K
2
0
S
2
1
F
2
2
A
2
5
F
2
6
L
2
9
V
3
7
I
4
0
Y
4
1
C
4
4
R
4
5
D
4
8
D
4
9
D
5
2
L
1
0
7
V
1
1
1
D
1
1
4
F
1
1
7
Y
1
2
9
V
1
3
3
A
1
3
4
V
1
3
7
G
1
3
8
L
1
4
1
L
1
4
5
A
1
5
7
L
1
6
0
G
1
6
1
L
1
6
4
Q
1
6
5
I
1
6
7
N
1
6
8
I
1
6
9
R
1
7
1
D
1
7
2
D
1
7
6
R
1
8
1
Y
1
8
3
F
2
3
3
I
2
4
0
I
2
4
1
L
2
4
3
A
2
4
4
A
2
4
5
I
2
4
7
Y
2
4
8
I
2
4
9
I
2
5
1
R
2
6
5
V
2
6
6
F
2
6
7
[1]2zco.a . . * * . . . . * . . . * . * * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . .
[1]2zcq.a . . * * . * . . * . . . . . * * . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . * . . Mg
[1]2zcr.a . . * * . . . . * . . . * . * * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . . Mg
[1]2zcs.a . . * * . . . . * . . . * . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . .
[1]2zy1.a . . * * . . . . * . . . . . * * . - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . .
[1]3acw.a . . * * . . . . * . . . * . * * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . .
[1]3acx.a . . * * . . . . * . . . * . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . .
[1]3acy.a . . * * . . . . * . . . . . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . . Mg
[1]3adz.a . . * * . . . . * . . . . . . * . . . . . . A . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . . Mg
[1]3npr.a . . * * . . . . * . . . . . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . * . . Mg
[1]3nri.a . . * * . . . . * . . . . . * * . - . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . .
[1]3tfn.a . . * * . . . . * . . . . . * * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . .
[1]3tfp.a . . * * . . . . * . . . . . * * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . . Mg
[1]3tfv.a . . * * . . * . * . . . * . * * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . . Mg
[1]4e9u.a . . * * . . * . * . . . * . * * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . * . .
[1]4ea0.a . . * * . . . . * . . . . . . * . * . . * . . . . . . . . . . . . . . * . . . . . . . . . . . . . * . . . . . Mg
[1]4ea1.a . . * * . . . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . .
[1]4ea2.a . . * * . . . . * . . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . .
[1]4f6v.a . . * * . . . . * . . . . . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . . Mg
[1]4f6x.a . . * * . . . . * . . . * . * * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . . Mg
[2]3ae0.b . . * . * * * . A . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . * . . Mg
[2]3vje.b . . . . * * . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . A . . * . .
[2]3w7f.b . . * . * * * . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . . Mg
[3]3vjd.a . . * * * * * . * . . . * . * * . . . . . . . . . . . . . . . . . . . * . . . . . . . . . . . . . A . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)

Pocket-ligand steric compatibility

Ligands (x) vs pockets (y) colored by number of steric clashes

zoom: [−] [+]; [view as image]; [download as text]

pocketligand
≥10
9
8
7
6
5
4
3
2
1
0
2zco.a is apo
2zcq.a:b65,mg
2zcr.a:b69
2zcs.a:b70
2zy1.a:830
3acw.a:651
3acx.a:673
3acy.a:702
3adz.a:mg,ps7
3npr.a:mg,ps7
3nri.a:dh7
3tfn.a:2cj,mg
3tfp.a:03l,mg
3tfv.a:2cn
4e9u.a:rwy
4ea0.a:651,mg
4ea1.a:3rx
4ea2.a:mg,rwz,srt
4f6v.a:fjp,mg,srt,zym
4f6x.a:mg,tar,zyl
3ae0.b:ggs,mg
3vje.b:zga
3w7f.b:fps,mg
3vjd.a is apo
[1] 2zco.a
-
2.3 0.1 0.5 0.3 0.5 1.4 1.5 5.8 5.8 1.4 1.6 2.5 0.9 0.4 1.1 0.2 1.8 4.8 0.9 8.7 15 6.3 -
[1] 2zcq.a -
0
0.4 0.7 0.2 0.1 0 1.1 0.8 0.8 1.7 0.7 0.6 1.0 0.2 0.5 2.9 0.8 2.1 1.2 4.7 9.2 1.3 -
[1] 2zcr.a - 1.4
0
0.6 0.3 0.1 1.0 2.0 4.8 4.8 0.6 1.3 1.7 1.1 0.3 0.5 1.1 1.1 3.9 0.7 7.2 13 4.6 -
[1] 2zcs.a - 1.1 0.1
0.2
0 0.1 0.6 0.8 3.3 3.5 0.8 1.0 1.9 0.5 0.3 0.4 0.2 0.6 2.9 0.1 6.2 13 3.3 -
[1] 2zy1.a - 0.9 0.2 0.2
0
0.2 0.9 0.5 1.8 1.8 1.3 0.8 2.0 0.7 0.3 0.5 0.5 0.8 1.4 0.5 5.7 11 2.4 -
[1] 3acw.a - 1.2 0.1 0.7 0.1
0
0.6 1.0 4.7 4.5 0.8 1.0 2.2 0.9 0.3 0.4 0.8 0.7 4.7 0.6 7.1 13 4.9 -
[1] 3acx.a - 0.5 0.1 0.6 0.2 0.2
0
1.2 2.5 2.2 0.3 0.7 1.3 0.5 0.1 0.1 1.1 0.2 2.4 0.7 6.2 10 2.9 -
[1] 3acy.a - 0.4 0.2 0.3 0.1 0.2 0.5
0
1.0 0.7 1.0 0.7 1.0 0.6 0.2 0.4 0.1 0.5 1.0 0.5 5.7 9.0 1.6 -
[1] 3adz.a - 0.1 0.1 0.4 0 0.1 0.1 1.0
0.2
0.1 0.6 0.6 0.4 0.5 0.2 0.2 0.8 0.2 0.8 0.8 4.1 9.0 1.0 -
[1] 3npr.a - 0 0.1 0.4 0 0 0.2 1.0 0.1
0.1
1.0 0.8 0.1 0.5 0.2 0.2 0.8 0.5 1.2 1.0 3.8 8.8 0.9 -
[1] 3nri.a - 0.4 0.2 0.4 0.4 0.1 0.4 0.9 1.3 1.2
0.2
0.5 1.1 1.0 0.4 0.3 1.3 0.4 0.9 0.3 4.6 9.8 1.8 -
[1] 3tfn.a - 0.5 0.4 0.5 0.4 0.4 0.6 0.1 1.0 0.9 1.1
0.1
0.8 0.7 0.3 0.4 0.2 1.0 0.8 0.8 5.5 9.7 1.5 -
[1] 3tfp.a - 0.3 0.3 0.5 0.4 0.5 0.9 1.3 2.9 2.9 0.8 1.1
0.4
0.3 0.3 0.3 1.1 0.7 2.6 1.0 6.6 12 3.7 -
[1] 3tfv.a - 1.3 0.6 0.6 0.6 0.6 1.5 1.9 3.2 3.2 0.5 1.7 1.6
0
0.6 0.8 1.3 0.7 2.2 0.7 6.7 12 3.9 -
[1] 4e9u.a - 2.4 0.5 0.5 0.4 0.4 2.8 2.5 6.3 5.8 1.9 2.7 2.1 0.6
0.4
0.9 0.4 2.0 5.2 1.5 11 14 6.3 -
[1] 4ea0.a - 0.8 1.3 1.6 0.4 0.4 0.2 1.6 1.7 1.6 1.4 1.0 1.2 1.3 0.6
0.3
3.2 0.5 1.6 1.4 7.6 10 3.7 -
[1] 4ea1.a - 0.1 0.2 0.6 0 0.1 0.4 0.3 0.5 0.4 0.7 0.9 0.6 0.6 0.2 0.4
0.2
0.4 0.5 0.3 5.0 9.3 1.4 -
[1] 4ea2.a - 0.1 0.1 0.4 0.1 0.1 0 1.2 2.5 2.5 0.5 0.6 0.8 0.4 0.3 0.1 0.4
0
2.2 0.6 6.3 11 2.8 -
[1] 4f6v.a - 0 0 0.2 0 0 0.2 0.9 0.2 0.1 0.2 0.6 0.4 0.2 0.3 0.2 0.5 0.1
0.3
0.4 3.7 8.4 0.7 -
[1] 4f6x.a - 1.8 0 0.3 0 0.1 1.3 1.0 5.5 5.5 1.2 1.1 2.6 1.1 0.3 1.1 0.1 1.5 4.9
0.6
7.7 15 5.2 -
[2] 3ae0.b - 0 0.1 0.1 0.1 0 0 0.5 0.1 0.1 3.5 0.7 0.2 0.4 0.2 0.1 0.6 2.6 2.9 3.7
0.4
8.9 0.3 -
[2] 3vje.b - 0 0.7 0.7 0.4 0.7 0.8 1.3 0.3 0.3 3.3 0.6 0.6 0.6 0.3 0.2 0.6 3.6 3.2 4.2 4.6
0.2
1.0 -
[2] 3w7f.b - 0 0.1 0.1 0 0 0.1 0.4 0 0 4.1 0.8 0 0.2 0.2 0.1 1.3 3.1 3.1 4.1 3.3 8.2
0.4
-
[3] 3vjd.a - 1.9 0.8 1.0 1.9 0.9 1.2 1.3 3.4 3.0 5.0 1.8 2.2 2.2 0.9 0.5 2.4 3.8 4.7 4.6 9.3 11 4.6
-
[Pocket-ligand steric clashes matrix]

Pocket clash dissimilarity (3 clusters)

Pockets (x) vs pockets (y) colored by ligand clash profile difference

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥1.
.9
.8
.7
.6
.5
.4
.3
.2
.1
.0
2zco.a
2zcq.a
2zcr.a
2zcs.a
2zy1.a
3acw.a
3acx.a
3acy.a
3adz.a
3npr.a
3nri.a
3tfn.a
3tfp.a
3tfv.a
4e9u.a
4ea0.a
4ea1.a
4ea2.a
4f6v.a
4f6x.a
3ae0.b
3vje.b
3w7f.b
3vjd.a
[1] 2zco.a
0
.20 .06 .08 .11 .05 .10 .13 .16 .18 .13 .12 .08 .08 .09 .22 .15 .11 .14 .06 .33 .33 .31 .37
[1] 2zcq.a .20
0
.20 .16 .12 .18 .15 .14 .12 .11 .14 .12 .16 .19 .21 .12 .13 .17 .12 .18 .27 .29 .20 .41
[1] 2zcr.a .06 .20
0
.06 .09 .03 .09 .12 .14 .17 .12 .11 .07 .07 .11 .22 .15 .09 .13 .05 .30 .34 .28 .37
[1] 2zcs.a .08 .16 .06
0
.06 .05 .06 .09 .11 .12 .09 .09 .07 .05 .12 .19 .11 .07 .09 .08 .28 .31 .25 .40
[1] 2zy1.a .11 .12 .09 .06
0
.08 .06 .06 .08 .10 .06 .06 .08 .09 .16 .16 .08 .08 .06 .09 .26 .27 .23 .37
[1] 3acw.a .05 .18 .03 .05 .08
0
.06 .11 .13 .14 .10 .10 .06 .05 .10 .21 .13 .09 .11 .05 .29 .32 .27 .38
[1] 3acx.a .10 .15 .09 .06 .06 .06
0
.09 .11 .12 .10 .09 .07 .09 .14 .17 .10 .06 .09 .10 .27 .28 .25 .40
[1] 3acy.a .13 .14 .12 .09 .06 .11 .09
0
.07 .08 .07 .04 .08 .11 .17 .15 .07 .08 .06 .13 .24 .24 .21 .38
[1] 3adz.a .16 .12 .14 .11 .08 .13 .11 .07
0
.03 .09 .07 .11 .12 .19 .14 .04 .10 .06 .13 .21 .24 .18 .40
[1] 3npr.a .18 .11 .17 .12 .10 .14 .12 .08 .03
0
.10 .09 .12 .13 .20 .16 .07 .12 .06 .15 .19 .22 .16 .39
[1] 3nri.a .13 .14 .12 .09 .06 .10 .10 .07 .09 .10
0
.08 .10 .10 .19 .17 .08 .11 .06 .12 .26 .28 .24 .39
[1] 3tfn.a .12 .12 .11 .09 .06 .10 .09 .04 .07 .09 .08
0
.07 .11 .16 .15 .07 .10 .07 .13 .24 .25 .22 .37
[1] 3tfp.a .08 .16 .07 .07 .08 .06 .07 .08 .11 .12 .10 .07
0
.06 .11 .17 .11 .09 .10 .08 .28 .29 .25 .39
[1] 3tfv.a .08 .19 .07 .05 .09 .05 .09 .11 .12 .13 .10 .11 .06
0
.11 .20 .13 .10 .09 .08 .26 .32 .25 .40
[1] 4e9u.a .09 .21 .11 .12 .16 .10 .14 .17 .19 .20 .19 .16 .11 .11
0
.25 .19 .16 .19 .11 .30 .37 .29 .33
[1] 4ea0.a .22 .12 .22 .19 .16 .21 .17 .15 .14 .16 .17 .15 .17 .20 .25
0
.15 .17 .17 .20 .32 .34 .26 .40
[1] 4ea1.a .15 .13 .15 .11 .08 .13 .10 .07 .04 .07 .08 .07 .11 .13 .19 .15
0
.09 .06 .13 .23 .25 .20 .41
[1] 4ea2.a .11 .17 .09 .07 .08 .09 .06 .08 .10 .12 .11 .10 .09 .10 .16 .17 .09
0
.10 .09 .27 .28 .25 .41
[1] 4f6v.a .14 .12 .13 .09 .06 .11 .09 .06 .06 .06 .06 .07 .10 .09 .19 .17 .06 .10
0
.11 .21 .25 .20 .42
[1] 4f6x.a .06 .18 .05 .08 .09 .05 .10 .13 .13 .15 .12 .13 .08 .08 .11 .20 .13 .09 .11
0
.30 .33 .28 .39
[2] 3ae0.b .33 .27 .30 .28 .26 .29 .27 .24 .21 .19 .26 .24 .28 .26 .30 .32 .23 .27 .21 .30
0
.25 .11 .39
[2] 3vje.b .33 .29 .34 .31 .27 .32 .28 .24 .24 .22 .28 .25 .29 .32 .37 .34 .25 .28 .25 .33 .25
0
.20 .27
[2] 3w7f.b .31 .20 .28 .25 .23 .27 .25 .21 .18 .16 .24 .22 .25 .25 .29 .26 .20 .25 .20 .28 .11 .20
0
.35
[3] 3vjd.a .37 .41 .37 .40 .37 .38 .40 .38 .40 .39 .39 .37 .39 .40 .33 .40 .41 .41 .42 .39 .39 .27 .35
0
[Pocket clash dissimilarity matrix]

Site backbone RMSD (median 1.0 Å)

Pockets (x) vs pockets (y) colored by RMSD of site residue backbone atoms

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥10 Å
9 Å
8 Å
7 Å
6 Å
5 Å
4 Å
3 Å
2 Å
1 Å
0 Å
2zco.a
2zcq.a
2zcr.a
2zcs.a
2zy1.a
3acw.a
3acx.a
3acy.a
3adz.a
3npr.a
3nri.a
3tfn.a
3tfp.a
3tfv.a
4e9u.a
4ea0.a
4ea1.a
4ea2.a
4f6v.a
4f6x.a
3ae0.b
3vje.b
3w7f.b
3vjd.a
[1] 2zco.a
0
1.1 0.3 0.3 0.4 0.3 0.4 0.4 0.5 0.5 0.3 0.3 0.3 0.4 0.2 1.0 0.5 0.5 0.5 0.3 1.0 1.2 1.0 1.2
[1] 2zcq.a 1.1
0
1.0 1.1 0.5 1.1 1.1 1.1 1.0 1.0 0.5 1.1 1.1 1.1 1.1 0.4 1.1 0.8 1.0 0.9 0.8 1.2 0.8 1.6
[1] 2zcr.a 0.3 1.0
0
0.2 0.2 0.1 0.3 0.3 0.4 0.4 0.3 0.4 0.3 0.4 0.3 1.0 0.4 0.5 0.3 0.3 1.0 1.3 1.0 1.3
[1] 2zcs.a 0.3 1.1 0.2
0
0.3 0.2 0.3 0.2 0.3 0.4 0.3 0.3 0.3 0.3 0.3 1.0 0.4 0.5 0.3 0.3 1.0 1.2 0.9 1.3
[1] 2zy1.a 0.4 0.5 0.2 0.3
0
0.2 0.3 0.3 0.4 0.4 0.3 0.5 0.4 0.5 0.4 0.6 0.5 0.3 0.3 0.3 0.8 1.2 0.8 1.3
[1] 3acw.a 0.3 1.1 0.1 0.2 0.2
0
0.2 0.2 0.4 0.4 0.3 0.4 0.3 0.4 0.4 1.1 0.4 0.5 0.3 0.3 1.0 1.3 1.0 1.4
[1] 3acx.a 0.4 1.1 0.3 0.3 0.3 0.2
0
0.2 0.4 0.4 0.4 0.4 0.4 0.5 0.4 1.0 0.5 0.5 0.3 0.4 1.0 1.3 1.0 1.4
[1] 3acy.a 0.4 1.1 0.3 0.2 0.3 0.2 0.2
0
0.3 0.3 0.3 0.4 0.3 0.4 0.4 1.0 0.4 0.5 0.3 0.4 1.0 1.3 1.0 1.4
[1] 3adz.a 0.5 1.0 0.4 0.3 0.4 0.4 0.4 0.3
0
0.1 0.4 0.4 0.4 0.5 0.5 1.0 0.3 0.5 0.3 0.5 0.9 1.2 0.9 1.4
[1] 3npr.a 0.5 1.0 0.4 0.4 0.4 0.4 0.4 0.3 0.1
0
0.4 0.4 0.4 0.5 0.5 1.0 0.3 0.6 0.3 0.5 0.8 1.1 0.8 1.4
[1] 3nri.a 0.3 0.5 0.3 0.3 0.3 0.3 0.4 0.3 0.4 0.4
0
0.3 0.3 0.3 0.3 0.6 0.4 0.3 0.3 0.3 0.8 1.1 0.7 1.3
[1] 3tfn.a 0.3 1.1 0.4 0.3 0.5 0.4 0.4 0.4 0.4 0.4 0.3
0
0.2 0.4 0.2 1.0 0.3 0.5 0.4 0.4 1.0 1.1 0.9 1.2
[1] 3tfp.a 0.3 1.1 0.3 0.3 0.4 0.3 0.4 0.3 0.4 0.4 0.3 0.2
0
0.3 0.2 1.1 0.4 0.5 0.4 0.4 1.0 1.1 0.9 1.3
[1] 3tfv.a 0.4 1.1 0.4 0.3 0.5 0.4 0.5 0.4 0.5 0.5 0.3 0.4 0.3
0
0.3 1.0 0.4 0.5 0.5 0.4 1.0 1.2 0.9 1.3
[1] 4e9u.a 0.2 1.1 0.3 0.3 0.4 0.4 0.4 0.4 0.5 0.5 0.3 0.2 0.2 0.3
0
1.0 0.5 0.5 0.5 0.3 1.0 1.2 1.0 1.2
[1] 4ea0.a 1.0 0.4 1.0 1.0 0.6 1.1 1.0 1.0 1.0 1.0 0.6 1.0 1.1 1.0 1.0
0
1.1 0.8 1.0 0.9 0.8 1.2 0.8 1.4
[1] 4ea1.a 0.5 1.1 0.4 0.4 0.5 0.4 0.5 0.4 0.3 0.3 0.4 0.3 0.4 0.4 0.5 1.1
0
0.6 0.3 0.5 1.0 1.2 0.9 1.4
[1] 4ea2.a 0.5 0.8 0.5 0.5 0.3 0.5 0.5 0.5 0.5 0.6 0.3 0.5 0.5 0.5 0.5 0.8 0.6
0
0.6 0.4 0.8 1.2 0.8 1.3
[1] 4f6v.a 0.5 1.0 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.4 0.4 0.5 0.5 1.0 0.3 0.6
0
0.5 1.0 1.3 1.0 1.5
[1] 4f6x.a 0.3 0.9 0.3 0.3 0.3 0.3 0.4 0.4 0.5 0.5 0.3 0.4 0.4 0.4 0.3 0.9 0.5 0.4 0.5
0
0.9 1.2 0.9 1.2
[2] 3ae0.b 1.0 0.8 1.0 1.0 0.8 1.0 1.0 1.0 0.9 0.8 0.8 1.0 1.0 1.0 1.0 0.8 1.0 0.8 1.0 0.9
0
0.8 0.3 1.3
[2] 3vje.b 1.2 1.2 1.3 1.2 1.2 1.3 1.3 1.3 1.2 1.1 1.1 1.1 1.1 1.2 1.2 1.2 1.2 1.2 1.3 1.2 0.8
0
0.8 1.4
[2] 3w7f.b 1.0 0.8 1.0 0.9 0.8 1.0 1.0 1.0 0.9 0.8 0.7 0.9 0.9 0.9 1.0 0.8 0.9 0.8 1.0 0.9 0.3 0.8
0
1.4
[3] 3vjd.a 1.2 1.6 1.3 1.3 1.3 1.4 1.4 1.4 1.4 1.4 1.3 1.2 1.3 1.3 1.2 1.4 1.4 1.3 1.5 1.2 1.3 1.4 1.4
0
[Binding site backbone RMSD matrix]

Site full-atom RMSD (median 0.5 Å)

Pockets (x) vs pockets (y) colored by RMSD of all site residue atoms

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥10 Å
9 Å
8 Å
7 Å
6 Å
5 Å
4 Å
3 Å
2 Å
1 Å
0 Å
2zco.a
2zcq.a
2zcr.a
2zcs.a
2zy1.a
3acw.a
3acx.a
3acy.a
3adz.a
3npr.a
3nri.a
3tfn.a
3tfp.a
3tfv.a
4e9u.a
4ea0.a
4ea1.a
4ea2.a
4f6v.a
4f6x.a
3ae0.b
3vje.b
3w7f.b
3vjd.a
[1] 2zco.a
0
1.5 0.6 0.5 0.8 0.7 0.9 1.0 1.1 1.1 0.9 0.9 0.6 0.7 0.6 1.5 1.2 1.0 1.0 0.6 1.6 1.7 1.5 1.8
[1] 2zcq.a 1.5
0
1.4 1.4 0.8 1.5 1.4 1.3 1.3 1.2 0.8 1.3 1.4 1.4 1.5 0.8 1.4 1.5 1.2 1.3 1.1 1.5 1.0 2.1
[1] 2zcr.a 0.6 1.4
0
0.5 0.8 0.6 0.8 0.9 1.0 1.1 0.9 1.0 0.7 0.7 0.8 1.4 1.2 0.9 0.9 0.7 1.5 1.7 1.4 1.9
[1] 2zcs.a 0.5 1.4 0.5
0
0.8 0.6 0.7 0.8 0.9 1.0 0.8 0.9 0.6 0.7 0.7 1.4 1.1 0.8 0.9 0.6 1.5 1.7 1.4 1.9
[1] 2zy1.a 0.8 0.8 0.8 0.8
0
0.9 0.9 0.7 0.7 0.8 0.6 0.8 0.9 0.9 1.0 1.0 0.8 0.8 0.6 0.8 1.2 1.5 1.1 1.9
[1] 3acw.a 0.7 1.5 0.6 0.6 0.9
0
0.6 0.8 1.1 1.1 0.9 1.0 0.7 0.8 0.9 1.5 1.2 0.9 1.0 0.8 1.5 1.7 1.5 1.9
[1] 3acx.a 0.9 1.4 0.8 0.7 0.9 0.6
0
0.8 1.0 1.0 0.9 1.0 0.7 0.9 1.0 1.4 1.1 0.8 0.9 0.9 1.5 1.7 1.5 1.9
[1] 3acy.a 1.0 1.3 0.9 0.8 0.7 0.8 0.8
0
0.8 0.8 0.7 0.8 0.9 1.0 1.1 1.3 0.9 1.1 0.7 1.0 1.2 1.5 1.3 1.9
[1] 3adz.a 1.1 1.3 1.0 0.9 0.7 1.1 1.0 0.8
0
0.3 0.6 0.6 1.0 0.9 1.2 1.3 0.6 1.0 0.7 1.1 1.2 1.4 1.2 1.9
[1] 3npr.a 1.1 1.2 1.1 1.0 0.8 1.1 1.0 0.8 0.3
0
0.6 0.7 0.9 0.9 1.1 1.2 0.6 1.0 0.7 1.1 1.1 1.3 1.1 1.9
[1] 3nri.a 0.9 0.8 0.9 0.8 0.6 0.9 0.9 0.7 0.6 0.6
0
0.6 0.8 0.8 1.0 0.9 0.6 0.8 0.6 0.9 1.1 1.3 1.0 1.8
[1] 3tfn.a 0.9 1.3 1.0 0.9 0.8 1.0 1.0 0.8 0.6 0.7 0.6
0
0.8 0.9 1.0 1.3 0.6 1.0 0.8 1.0 1.3 1.4 1.3 1.8
[1] 3tfp.a 0.6 1.4 0.7 0.6 0.9 0.7 0.7 0.9 1.0 0.9 0.8 0.8
0
0.7 0.7 1.4 1.1 0.8 0.9 0.8 1.4 1.6 1.4 1.8
[1] 3tfv.a 0.7 1.4 0.7 0.7 0.9 0.8 0.9 1.0 0.9 0.9 0.8 0.9 0.7
0
0.8 1.4 1.0 0.9 0.9 0.8 1.4 1.6 1.4 1.9
[1] 4e9u.a 0.6 1.5 0.8 0.7 1.0 0.9 1.0 1.1 1.2 1.1 1.0 1.0 0.7 0.8
0
1.5 1.2 1.0 1.1 0.8 1.6 1.7 1.5 1.9
[1] 4ea0.a 1.5 0.8 1.4 1.4 1.0 1.5 1.4 1.3 1.3 1.2 0.9 1.3 1.4 1.4 1.5
0
1.4 1.5 1.3 1.3 1.2 1.5 1.1 1.9
[1] 4ea1.a 1.2 1.4 1.2 1.1 0.8 1.2 1.1 0.9 0.6 0.6 0.6 0.6 1.1 1.0 1.2 1.4
0
1.0 0.8 1.2 1.3 1.4 1.3 1.9
[1] 4ea2.a 1.0 1.5 0.9 0.8 0.8 0.9 0.8 1.1 1.0 1.0 0.8 1.0 0.8 0.9 1.0 1.5 1.0
0
1.0 1.0 1.5 1.7 1.5 2.0
[1] 4f6v.a 1.0 1.2 0.9 0.9 0.6 1.0 0.9 0.7 0.7 0.7 0.6 0.8 0.9 0.9 1.1 1.3 0.8 1.0
0
1.1 1.3 1.5 1.2 1.9
[1] 4f6x.a 0.6 1.3 0.7 0.6 0.8 0.8 0.9 1.0 1.1 1.1 0.9 1.0 0.8 0.8 0.8 1.3 1.2 1.0 1.1
0
1.4 1.6 1.4 1.8
[2] 3ae0.b 1.6 1.1 1.5 1.5 1.2 1.5 1.5 1.2 1.2 1.1 1.1 1.3 1.4 1.4 1.6 1.2 1.3 1.5 1.3 1.4
0
1.1 0.9 1.9
[2] 3vje.b 1.7 1.5 1.7 1.7 1.5 1.7 1.7 1.5 1.4 1.3 1.3 1.4 1.6 1.6 1.7 1.5 1.4 1.7 1.5 1.6 1.1
0
1.1 1.8
[2] 3w7f.b 1.5 1.0 1.4 1.4 1.1 1.5 1.5 1.3 1.2 1.1 1.0 1.3 1.4 1.4 1.5 1.1 1.3 1.5 1.2 1.4 0.9 1.1
0
1.9
[3] 3vjd.a 1.8 2.1 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.9 1.8 1.8 1.8 1.9 1.9 1.9 1.9 2.0 1.9 1.8 1.9 1.8 1.9
0
[Binding site full-atom RMSD matrix]







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[ENTRY 2D visualization]

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