CRFR1_HUMAN_24_112_ECD

Corticotropin-releasing factor receptor 1 [G-protein coupled receptor 2 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (CRFR1_HUMAN):R: Important for peptide agonist binding (99,102:104)
50,51,69,72,73,75,77,96,97
50,51,69,72,73,75,77,96,97,99,102:104

Full PDB list

3ehs,3eht,3ehu

Contact map

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ligand
A1
L
5
0
I
5
1
P
6
9
F
7
2
Y
7
3
V
7
5
Y
7
7
R
9
6
V
9
7
Y
9
9
C
1
0
2
Q
1
0
3
E
1
0
4
[1]3ehu.b QLAQQAHSNRKLMEIInh2 123 . . . . . . . . . . . . .
[3]3ehs.a none . . . . . . . . . . . . .
[2]3eht.a AHSNRKLMEIInh2 91 . . . . . . . . . . . . -

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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