CRFR1_HUMAN_112_401_TM

Corticotropin-releasing factor receptor 1 [G-protein coupled receptor 2 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (CRFR1_HUMAN):R: Important for antagonist binding (309,312,313)
191,232,235,239,345,349,352,356
191,232,235,239,309,312,313,345,349,352,356

Full PDB list

4k5y,4z9g (redundant pocketome entry)

Contact map

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ligand
A1
F
1
9
1
F
2
3
2
M
2
3
5
G
2
3
9
L
3
0
9
N
3
1
2
F
3
1
3
T
3
4
5
L
3
4
9
L
3
5
2
Y
3
5
6
[1]4k5y.a 1q5 24 . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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