CRBN_CHICK_320_432

Protein cereblon [CRBN family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (CRBN_CHICK):D: CULT (353:355,359,379:382,388,402,404)
R: Thalidomide binding (380:382,388)
353:355,359,379:382,388,402,404
Metals (Me):Zn

Full PDB list

4ci1,4ci2,4ci3

Contact map

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ligand
A1 Me
N
3
5
3
P
3
5
4
H
3
5
5
H
3
5
9
E
3
7
9
H
3
8
0
S
3
8
1
W
3
8
2
W
3
8
8
W
4
0
2
F
4
0
4
[1]4ci3.b y70 20 . . . . . . . . . . . Zn
[1]4ci1.b ef2 19 . . . . . . . . . . . Zn
[1]4ci2.b lvy 19 . . . . . . . . . . . Zn

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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