CPNS1_HUMAN_93_267

Calpain small subunit 1

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (CPNS1_HUMAN):D: EF-hand 1
atypical (101,104,105,107,108,123,124)
D: EF-hand 2 (139,164,168,171,172)
D: EF-hand 3 (171,172,175,176,179)
D: EF-hand 4 (226)
126:128,130,131,134
101,104,105,107,108,123,124,126:128,130,131,134,139,164,168,171,172,175,176,179,226
Metals (Me):Ca

Full PDB list

1aj5,1alv,1alw,1df0,1dvi,1kfu,1kfx,1np8,1nx0,1nx1,1nx2,1nx3,1u5i,3bow,3df0,4phj,4phk,4phm,4phn,4wq2,4wq3,5d69 (redundant pocketome entry)

Contact map

[download in TSV format]
   
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ligand
A1 Me
F
1
0
1
L
1
0
4
F
1
0
5
Q
1
0
7
L
1
0
8
I
1
2
3
L
1
2
4
K
1
2
6
V
1
2
7
V
1
2
8
R
1
3
0
H
1
3
1
L
1
3
4
F
1
3
9
F
1
6
4
W
1
6
8
I
1
7
1
K
1
7
2
Q
1
7
5
A
1
7
6
K
1
7
9
F
2
2
6
[1]5d69.a 57t 26 . . . . . . . . . . . . . . . . . . . . . . Ca
[1]4phm.a 2ud 16 . . . . . . . . . . . . . . . . . . . . . . Ca
[1]4wq2.a 3su 16 . . . . . . . . . . . . . . . . . . . . . . Ca
[1]4phk.a 2ub 13 . . . . . . . . . . . . . . . . . . . . . . Ca
[1]1alw.a isa 13 . . . . . . . . . . . . . . . . . . . . . . Ca
[2]1aj5.b none . . . . . . . . . . - - . . . . . . . G . .
[1]4wq3.a 3su,3su 32 . . . . . . . . . . . . . . . . . . . . . . Ca
[3]1kfu.s none . . . . . . . . . . . . . . . . . . . . . .
[1]1nx0.a DAIDALSSDFTS 87 . . . . . . . . . . . . . . . . . . . . . . Ca
[1]1nx1.a DAIDALSSDFT 81 . . . . . . . . . . . . . . . . . . . . . . Ca
[1]3bow.b QDPIDALSEDLD 92 . . . . . . . . . . . . . . . . . . . G . .
[1]3df0.b HAIDALSSDFT 83 . . . . . . . . . . . . . . . . . . . G . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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