CP51_CANGA_20_533

Lanosterol 14-alpha demethylase [Cytochrome P450 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (CP51_CANGA):70,73:75,127,135,140,141,237,239,242,311,312,315,319,381:383,385,509:51270,73:75,127,135,140,141,237,239,242,311,312,315,319,381:383,385,509:512
Cofactors (cF):hem
Metals (Me):Fe

Full PDB list

5jlc

Contact map

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ligand
A1 cF Me
A
7
0
Y
7
3
G
7
4
T
7
5
Y
1
2
7
F
1
3
5
I
1
4
0
Y
1
4
1
F
2
3
7
P
2
3
9
F
2
4
2
G
3
1
1
V
3
1
2
G
3
1
5
T
3
1
9
L
3
8
1
H
3
8
2
S
3
8
3
F
3
8
5
F
5
0
9
T
5
1
0
S
5
1
1
M
5
1
2
[1]5jlc.a 1yn 49 . . . . . . . . . . . . . . . . . . . . . . . hem Fe

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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