CP51A_HUMAN_57_503

Lanosterol 14-alpha demethylase [Cytochrome P450 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (CP51A_HUMAN):77,100,101,105,107,131,134,135,139,144,145,152,159,234:236,239,304,307,308,310,311,315,377,379,381,402,487,48877,100,101,105,107,131,134,135,139,144,145,152,159,234:236,239,304,307,308,310,311,315,377,379,381,402,487,488
Cofactors (cF):hem
Metals (Me):Fe

Full PDB list

3jus,3juv,3ld6,4uhi,4uhl (redundant pocketome entry)

Contact map

[download in TSV format]
   
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ligand
A1 cF Me
F
7
7
M
1
0
0
V
1
0
1
F
1
0
5
Y
1
0
7
Y
1
3
1
L
1
3
4
T
1
3
5
F
1
3
9
A
1
4
4
Y
1
4
5
F
1
5
2
L
1
5
9
F
2
3
4
S
2
3
5
H
2
3
6
W
2
3
9
M
3
0
4
G
3
0
7
L
3
0
8
L
3
1
0
A
3
1
1
T
3
1
5
I
3
7
7
I
3
7
9
M
3
8
1
C
4
0
2
M
4
8
7
I
4
8
8
[1]3jus.a ecl,ecn 48 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . hem Fe
[1]3ld6.a kkk 36 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . hem Fe
[1]4uhi.a vfv,vfv 82 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . hem Fe
[2]3juv.a none . . . . . . . . . . . . . . . . . . . . . . . . . . . . . hem Fe

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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