CP2C9_HUMAN_20_490_peripheralWarfarin

Cytochrome P450 2C9 [Cytochrome P450 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (CP2C9_HUMAN):97,98,100,102,103,113,114,208,217,364:367,388,47697,98,100,102,103,113,114,208,217,364:367,388,476
Cofactors (cF):hec
Metals (Me):Fe

Full PDB list

1og2,1og5,1r9o,4nz2,5a5i,5a5j (redundant pocketome entry)

Contact map

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ligand
A1 cF Me
R
9
7
G
9
8
F
1
0
0
L
1
0
2
A
1
0
3
V
1
1
3
F
1
1
4
L
2
0
8
N
2
1
7
T
3
6
4
S
3
6
5
L
3
6
6
P
3
6
7
L
3
8
8
F
4
7
6
[1]1og5.a swf 23 . . . . . . . . . . . . . . . hec Fe
[1]1og2.a none . . . . . . . . . . . . . . . hec Fe

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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