CP2C9_HUMAN_20_490_catalytic

Cytochrome P450 2C9 [Cytochrome P450 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (CP2C9_HUMAN):107,108,113,114,201,204,205,208,209,233,237,240,292,293,296,297,300,301,304,362,366,474,476,477,479107,108,113,114,201,204,205,208,209,233,237,240,292,293,296,297,300,301,304,362,366,474,476,477,479
Cofactors (cF):hec/hem
Metals (Me):Fe

Full PDB list

1og2,1og5,1r9o,4nz2,5a5i,5a5j (redundant pocketome entry)

Contact map

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ligand
A1 cF Me
N
1
0
7
R
1
0
8
V
1
1
3
F
1
1
4
L
2
0
1
N
2
0
4
I
2
0
5
L
2
0
8
S
2
0
9
L
2
3
3
V
2
3
7
M
2
4
0
V
2
9
2
D
2
9
3
G
2
9
6
A
2
9
7
E
3
0
0
T
3
0
1
T
3
0
4
L
3
6
2
L
3
6
6
N
4
7
4
F
4
7
6
A
4
7
7
V
4
7
9
[1]1r9o.a flp 18 . . . . . . . . . . . . . . . . . . . . . . . . . hem Fe
[1]4nz2.a 2qj 27 . . . . . . . . . . . . . . . . . . . . . . . . . hem Fe
[1]5a5j.a 6yf 28 . . . . . . . . . . . . . . . . . . . . . . . . . hem Fe
[1]5a5i.a xi1 24 . . . . . . . . . . . . . . . . . . . . . . . . . hem Fe
[1]1og5.a none . . . . . . . . . . . . . . . . . . . . . . . . . hec Fe

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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