If you see this message after the page is completely loaded, then JavaScript is not supported or disabled in your browser. Please consider enabling JavaScript for this site.

CP2B6_HUMAN_20_491_peripheralCM52

Cytochrome P450 2B6 [Cytochrome P450 family]

Composition of the binding site

Protein chains monomer
A1 (CP2B6_HUMAN):43, 44, 46:48, 50, 51, 212, 215, 216, 21943, 44, 46:48, 50, 51, 212, 215, 216, 219

Full PDB list

3ibd, 3qoa, 3qu8, 3ua5, 4i91, 4rql, 4rrt, 4zv8, 5uap, 5uda, 5uec, 5ufg (redundant Pocketome entry)

Pocket contact map

[download in TSV format]
   
PDB.ch
   
ligand
A1
D
4
7
R
4
8
G
5
0
L
5
1
V
2
1
2
Q
2
1
5
[1]3qu8.a none . . . . . .
[1]5uda.a cm512 . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)

Site contact map

[download in TSV format]
   
PDB.ch
A1
L
4
3
L
4
4
M
4
6
D
4
7
R
4
8
G
5
0
L
5
1
V
2
1
2
Q
2
1
5
L
2
1
6
L
2
1
9
[1]3qu8.a . . . . . . . . . . .
[1]5uda.a . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)

Pocket-ligand steric compatibility

Ligands (x) vs pockets (y) colored by number of steric clashes

zoom: [−] [+]; [view as image]; [download as text]

pocketligand
≥10
9
8
7
6
5
4
3
2
1
0
3qu8.a is apo
5uda.a:cm5
[1] 3qu8.a
-
0
[1] 5uda.a -
0
[Pocket-ligand steric clashes matrix]

Pocket clash dissimilarity (1 cluster)

Pockets (x) vs pockets (y) colored by ligand clash profile difference

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥1.
.9
.8
.7
.6
.5
.4
.3
.2
.1
.0
3qu8.a
5uda.a
[1] 3qu8.a
0
0
[1] 5uda.a 0
0
[Pocket clash dissimilarity matrix]

Site backbone RMSD (median 0.1 Å)

Pockets (x) vs pockets (y) colored by RMSD of site residue backbone atoms

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥10 Å
9 Å
8 Å
7 Å
6 Å
5 Å
4 Å
3 Å
2 Å
1 Å
0 Å
3qu8.a
5uda.a
[1] 3qu8.a
0
0.2
[1] 5uda.a 0.2
0
[Binding site backbone RMSD matrix]

Site full-atom RMSD (median 0.1 Å)

Pockets (x) vs pockets (y) colored by RMSD of all site residue atoms

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥10 Å
9 Å
8 Å
7 Å
6 Å
5 Å
4 Å
3 Å
2 Å
1 Å
0 Å
3qu8.a
5uda.a
[1] 3qu8.a
0
0.3
[1] 5uda.a 0.3
0
[Binding site full-atom RMSD matrix]







[show 3D visualization]

[ENTRY 2D visualization]

L C X E | Background Color: | Anaglyph Stereo:

loading...