CP2B6_HUMAN_20_491_peripheralAmlodipine

Cytochrome P450 2B6 [Cytochrome P450 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (CP2B6_HUMAN):49,51,73,215,218,219,365,368,389,476,47749,51,73,215,218,219,365,368,389,476,477
Cofactors (cF):cm5
Metals (Me):Fe

Full PDB list

3ibd,3qoa,3qu8,3ua5,4i91,4rql,4rrt,4zv8 (redundant pocketome entry)

Contact map

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ligand
A1 cF Me
R
4
9
L
5
1
R
7
3
Q
2
1
5
E
2
1
8
L
2
1
9
M
3
6
5
P
3
6
8
F
3
8
9
G
4
7
6
V
4
7
7
[1]3ua5.a 06x 28 . . . . . . . . . . . Fe
[2]3qoa.a none . . . . . . . . . . . cm5 Fe

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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