CP19A_HUMAN_41_503

Aromatase [Cytochrome P450 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (CP19A_HUMAN):115,133,134,221,224,306,309,310,313,370,372:374,477,478115,133,134,221,224,306,309,310,313,370,372:374,477,478
Cofactors (cF):hem
Metals (Me):Fe

Full PDB list

3eqm,3s79,3s7s,4gl5,4kq8 (redundant pocketome entry)

Contact map

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ligand
A1 cF Me
R
1
1
5
I
1
3
3
F
1
3
4
F
2
2
1
W
2
2
4
A
3
0
6
D
3
0
9
T
3
1
0
V
3
1
3
V
3
7
0
L
3
7
2
V
3
7
3
M
3
7
4
L
4
7
7
S
4
7
8
[1]4gl5.a g29 26 . . . . . . . . . . . . . . . hem Fe
[1]3s7s.a exm 22 . . . . . . . . . . . . . . . hem Fe
[1]3s79.a asd 21 . . . . . . . . . . . . . . . hem Fe

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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