If you see this message after the page is completely loaded, then JavaScript is not supported or disabled in your browser. Please consider enabling JavaScript for this site.

CP120_SYNY3_1_444

Putative cytochrome P450 120 [Cytochrome P450 family]

Composition of the binding site

Protein chains monomer
A1 (CP120_SYNY3):29, 80, 84, 94, 182, 250, 253, 254, 258, 318:320, 345, 42829, 80, 84, 94, 182, 250, 253, 254, 258, 318:320, 345, 428
Cofactors (cF):hem
Metals (Me):Fe

Full PDB list

2ve3, 2ve4

Pocket contact map

[download in TSV format]
   
PDB.ch
   
ligand
A1 cF Me
F
2
9
W
8
0
T
8
4
A
9
4
F
1
8
2
L
2
5
0
F
2
5
3
A
2
5
4
T
2
5
8
V
3
1
8
G
3
1
9
G
3
2
0
Q
3
4
5
P
4
2
8
[1]2ve3.a rea22 . . . . . . . . . . . . . . hem Fe
[1]2ve4.a none . . . . . . . . . . . . . . hem Fe

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)

Site contact map

[download in TSV format]
   
PDB.ch
A1 cF Me
F
2
9
W
8
0
T
8
4
A
9
4
F
1
8
2
L
2
5
0
F
2
5
3
A
2
5
4
T
2
5
8
V
3
1
8
G
3
1
9
G
3
2
0
Q
3
4
5
P
4
2
8
[1]2ve3.a . . . . . . . . . . . . . . hem Fe
[1]2ve4.a . . . . . . . . . . . . . . hem Fe

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)

Pocket-ligand steric compatibility

Ligands (x) vs pockets (y) colored by number of steric clashes

zoom: [−] [+]; [view as image]; [download as text]

pocketligand
≥10
9
8
7
6
5
4
3
2
1
0
2ve3.a:rea
2ve4.a is apo
[1] 2ve3.a
0
-
[1] 2ve4.a 0.5
-
[Pocket-ligand steric clashes matrix]

Pocket clash dissimilarity (1 cluster)

Pockets (x) vs pockets (y) colored by ligand clash profile difference

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥1.
.9
.8
.7
.6
.5
.4
.3
.2
.1
.0
2ve3.a
2ve4.a
[1] 2ve3.a
0
.04
[1] 2ve4.a .04
0
[Pocket clash dissimilarity matrix]

Site backbone RMSD (median 1.0 Å)

Pockets (x) vs pockets (y) colored by RMSD of site residue backbone atoms

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥10 Å
9 Å
8 Å
7 Å
6 Å
5 Å
4 Å
3 Å
2 Å
1 Å
0 Å
2ve3.a
2ve4.a
[1] 2ve3.a
0
1.6
[1] 2ve4.a 1.6
0
[Binding site backbone RMSD matrix]

Site full-atom RMSD (median 0.8 Å)

Pockets (x) vs pockets (y) colored by RMSD of all site residue atoms

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥10 Å
9 Å
8 Å
7 Å
6 Å
5 Å
4 Å
3 Å
2 Å
1 Å
0 Å
2ve3.a
2ve4.a
[1] 2ve3.a
0
2.0
[1] 2ve4.a 2.0
0
[Binding site full-atom RMSD matrix]







[show 3D visualization]

[ENTRY 2D visualization]

L C X E | Background Color: | Anaglyph Stereo:

loading...