COMP_HUMAN_28_72

Cartilage oligomeric matrix protein [Thrombospondin family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains homopentamer[show domain annotation]
 • A1 (COMP_HUMAN):R: COMP N-terminal (59,62,66,71,72)59,62,66,71,72
 • A2 (COMP_HUMAN):R: COMP N-terminal (59,62,66,69,71,72)59,62,66,69,71,72
 • A3 (COMP_HUMAN):R: COMP N-terminal (59,62,66,69,71,72)59,62,66,69,71,72
 • A4 (COMP_HUMAN):R: COMP N-terminal (59,62,66,69,71)59,62,66,69,71
 • A5 (COMP_HUMAN):R: COMP N-terminal (59,62,66,69,71,72)59,62,66,69,71,72
Cofactors (cF):myr/ste

Full PDB list

1fbm,1mz9,1vdf,3v2n,3v2p,3v2q,3v2r (redundant pocketome entry)

Contact map

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ligand
A1 A2 A3 A4 A5 cF
I
5
9
L
6
2
V
6
6
A
7
1
C
7
2
I
5
9
L
6
2
V
6
6
C
6
9
A
7
1
C
7
2
I
5
9
L
6
2
V
6
6
C
6
9
A
7
1
C
7
2
I
5
9
L
6
2
V
6
6
C
6
9
A
7
1
I
5
9
L
6
2
V
6
6
C
6
9
A
7
1
C
7
2
[1]1mz9.a vdy 29 . . . . . . . . . . . . . . . . . . . . - - . . . . . .
[1]1mz9.b vdy 29 . . . . . . . . . . . . . . . . . . . . . . . . . - - -
[1]1mz9.c vdy 29 . . . . . . . . . . . . . . - - - . . . . . . . . . . .
[1]1mz9.d vdy 29 . . . - - . . . . . . . . . . . . . . . . . . . . . . .
[1]3v2p.a none . . . . . . . . . . . . . . . . . . . . . . . . . . . . ste
[1]3v2p.b none . . . . . . . . . . . . . . . . . . . . . . . . . . . . ste
[1]3v2p.c none . . . . . . . . . . . . . . . . . . . . . . . . . . . . ste
[1]3v2p.d none . . . . . . . . . . . . . . . . . . . . . . . . . . . . ste
[1]3v2n.a none . . . . . . . . . . . . . . . . . . . . . . . . . . . . myr

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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