CHIT1_HUMAN_20_389

Chitotriosidase-1 [Glycosyl hydrolase 18 family. Chitinase class II subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (CHIT1_HUMAN):R: Chitooligosaccharide binding (98:100)
R: Chitooligosaccharide binding (210,212,213)
27,31,35,58,138,140,141,145,183,186,187,190,218,267,269,297,300,356,358
27,31,35,58,98:100,138,140,141,145,183,186,187,190,210,212,213,218,267,269,297,300,356,358

Full PDB list

1guv,1hki,1hkj,1hkk,1hkm,1lg1,1lg2,1lq0,1waw,1wb0,4wjx,4wk9,4wka,4wkf,4wkh,5hbf (redundant pocketome entry)

Contact map

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ligand
A1
Y
2
7
W
3
1
R
3
5
F
5
8
G
9
8
W
9
9
N
1
0
0
D
1
3
8
E
1
4
0
Y
1
4
1
Q
1
4
5
A
1
8
3
A
1
8
6
G
1
8
7
Y
1
9
0
M
2
1
0
Y
2
1
2
D
2
1
3
W
2
1
8
Y
2
6
7
R
2
6
9
E
2
9
7
M
3
0
0
M
3
5
6
W
3
5
8
[1]1hkm.a naa.naa.ali 42 . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1hkk.a naa.naa.ami,naa.naa.ami 86 . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1hkj.a na1.naa.ami 44 . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4wkh.a cbs 29 . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1lg2.a none . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1waw.a 0ar.dprDHun1 48 . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1wb0.a vr0.mea.ias.ias.dal 48 . . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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