CFAD_HUMAN_25_253

Complement factor D [Peptidase S1 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (CFAD_HUMAN):D: Peptidase S1 (49:51,66,67,69,153:155,162,203:208,222:227,229)49:51,66,67,69,153:155,162,203:208,222:227,229

Full PDB list

1bio,1dfp,1dic,1dst,1dsu,1fdp,1hfd,2xw9,2xwa,4cbn,4cbo,4d9q,4d9r,5fbe,5fbi,5fck,5tca,5tcc (redundant pocketome entry)

Contact map

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ligand
A1
H
4
9
L
5
0
C
5
1
H
6
6
C
6
7
E
6
9
W
1
5
3
G
1
5
4
I
1
5
5
R
1
6
2
S
2
0
3
C
2
0
4
K
2
0
5
G
2
0
6
D
2
0
7
S
2
0
8
V
2
2
2
T
2
2
3
S
2
2
4
G
2
2
5
S
2
2
6
R
2
2
7
C
2
2
9
[1]5fbe.a 5w5 33 . . . . . . . . . . . . . . . . . . . . . . .
[1]5fck.a 5wc 34 . . . . . - . . . . . . . . . . . . . . . . .
[1]5tca.b j55 30 . . . . . . . . . . . . . . . . . . . . . . .
[1]5tcc.d j56 27 . . . . . . . . . . . . . . . . . . . . . . .
[1]5fbi.a 5wd 23 . . . . . . . . . . . . . . . . . . . . . . .
[1]1dic.a dic.o,o 12 . . . . . . . . . . . . . . . * . . . . . . .
[1]1dfp.b dfp 10 . . . . . . . . . . . . . . . * . . . . . . .
[1]1bio.a soa 9 . . . . . . . . . . . . . . . * . . . . . . .
[2]1dst.a none . . . . . . . . . . . . . . . . . S W . . . .
[1]1dsu.a none . . . . . . . . . . . . . . . . . . . . . . .
[1]2xw9.a none . . . . . . . . . . . . . . . A . . . . . . .
[3]4cbo.b none . . . . . . . . . . . . . . . . . . . . . A .
[1]4d9q.a none . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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