CEAS_STRCL_1_573

N(2)-(2-carboxyethyl)arginine synthase [TPP enzyme family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains homodimer[show domain annotation]
 • A1 (CEAS_STRCL):R: Thiamine pyrophosphate binding (410:413)
R: Substrate binding (414,415)
R: Thiamine pyrophosphate binding (436:438)
R: Thiamine pyrophosphate binding (464,465)
R: Thiamine pyrophosphate binding (490,492:495)
271,301,303,306,462,463,496,499,561,571,573
271,301,303,306,410:415,436:438,462:465,490,492:496,499,561,571,573
 • A2 (CEAS_STRCL):33:36,57,80,83,84,87,120,12133:36,57,80,83,84,87,120,121
Metals (Me):Mg

Full PDB list

1upa,1upb,1upc,2iht,2ihu,2ihv (redundant pocketome entry)

Contact map

[download in TSV format]
   
PDB.ch
   
ligand
A1 A2 Me
Y
2
7
1
D
3
0
1
R
3
0
3
M
3
0
6
I
4
1
0
G
4
1
1
F
4
1
2
F
4
1
3
R
4
1
4
H
4
1
5
S
4
3
6
S
4
3
7
F
4
3
8
G
4
6
2
D
4
6
3
G
4
6
4
G
4
6
5
N
4
9
0
T
4
9
2
N
4
9
3
G
4
9
4
L
4
9
5
I
4
9
6
Y
4
9
9
Y
5
6
1
L
5
7
1
I
5
7
3
V
3
3
V
3
4
G
3
5
R
3
6
E
5
7
T
8
0
P
8
3
G
8
4
N
8
7
H
1
2
0
Q
1
2
1
[1]2ihu.a tar,tp9 35 . . . . . . . . . . . . . . . . . . . . . . . . . . - . . . . . . . . . . . Mg
[1]2ihu.b tp9 25 . . . . . . . . . . . . . . . . . . . . . . . . . - - . . . . . . . . . . . Mg
[1]2ihu.c tp8,tp9 60 . . . . . . . . . . . . . . . . . . . . . . . . . - - . . . . . . . . . . . Mg
[1]2ihv.a gva,tpp 37 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Mg
[1]1upb.b tpp 26 . . . . . . . . . . . . . . . . . . . . . . . . . . - . . . . . . . . . . . Mg
[1]2iht.b tpp 26 . . . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Mg

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
Similar entries
Feedback