CDKL5_HUMAN_1_303

Cyclin-dependent kinase-like 5 [Protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (CDKL5_HUMAN):D: Protein kinase (19,24,27,40,42,89:95,98,139,142,152,153)19,24,27,40,42,89:95,98,139,142,152,153
Metals (Me):Na

Full PDB list

4bgq

Contact map

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ligand
A1 Me
V
1
9
Y
2
4
V
2
7
A
4
0
K
4
2
F
8
9
E
9
0
Y
9
1
V
9
2
E
9
3
K
9
4
N
9
5
E
9
8
E
1
3
9
L
1
4
2
C
1
5
2
D
1
5
3
[1]4bgq.a 38r 27 . . . . . . . . . . . . . . . . . Na

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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