CDK6_HUMAN_1_312

Cyclin-dependent kinase 6 [Protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (CDK6_HUMAN):D: Protein kinase (19,20,24,27,41,43,61,77,98:104,106,107,149,150,152,162,163,166:168)19,20,24,27,41,43,61,77,98:104,106,107,149,150,152,162,163,166:168

Full PDB list

1bi7,1bi8,1blx,1g3n,1jow,1xo2,2euf,2f2c,3nup,3nux,4aua,4ez5,4tth,5l2i,5l2s,5l2t (redundant pocketome entry)

Contact map

[download in TSV format]
   
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ligand
A1
I
1
9
G
2
0
Y
2
4
V
2
7
A
4
1
K
4
3
E
6
1
V
7
7
F
9
8
E
9
9
H
1
0
0
V
1
0
1
D
1
0
2
Q
1
0
3
D
1
0
4
T
1
0
6
T
1
0
7
Q
1
4
9
N
1
5
0
L
1
5
2
A
1
6
2
D
1
6
3
L
1
6
6
A
1
6
7
R
1
6
8
[1]4tth.b 24v 31 . . - . . . . . . . . . . . . . . . . . . . . . .
[1]3nux.a 3nv 28 . . - . . . . . . . . . . . . . . . . . . . . . -
[1]5l2t.a 6zz 32 . . . . . . . . . . . . . . . . . . . . . . . . -
[1]2f2c.b ap9 28 . . - . . . . . . . . . . . . . . . . . . . . . .
[1]4ez5.a 0rs 36 . . - . . . . . . . . . . . . . . . . . . . . . -
[1]5l2s.a 6zv 37 . . . . . . . . . . . . . . . . . . . . . . . . -
[1]2euf.b lqq 33 . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3nup.a 3nu 22 . . - . . . . . . . . . . . . . . . . . . . . - -
[1]1xo2.b fse 21 . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4aua.a 4au 16 . . - . . . . . . . . . . . . . . . . . . . . . -
[2]1bi7.a RGR-M 34 . . . . . . - . . . . . . . . . . . . . . . . . .
[2]1bi8.a RGD-M 31 . . . . . . - . . . . . . . . . . . . . . . . . .
[1]1blx.a RG-M 23 . . . . . . . . . . . . . . . . . . . . . . . . .
[2]1g3n.a RG-K 24 . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1jow.b none - - . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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