CDC7_HUMAN_36_574

Cell division cycle 7-related protein kinase [Protein kinase superfamily. Ser/Thr protein kinase family. CDC7 subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (CDC7_HUMAN):D: Protein kinase (64:67,70,72,88,90,118,134:137,139,181,182,184,195,196)64:67,70,72,88,90,118,134:137,139,181,182,184,195,196
Metals (Me):Mg

Full PDB list

4f99,4f9a,4f9b,4f9c (redundant pocketome entry)

Contact map

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ligand
A1 Me
I
6
4
G
6
5
E
6
6
G
6
7
S
7
0
V
7
2
A
8
8
K
9
0
M
1
1
8
M
1
3
4
P
1
3
5
Y
1
3
6
L
1
3
7
H
1
3
9
S
1
8
1
N
1
8
2
L
1
8
4
V
1
9
5
D
1
9
6
[1]4f9c.a 0sx 20 . . . . . . . . . . . . . . . . . . .
[1]4f9b.a 0sy 16 . . . . . . . . . . . . . . . . . . .
[1]4f9a.c adp 27 . . . . . . . . . . . . . . . . . . . Mg

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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